Results 11 to 20 of about 398,969 (379)
And Now, Transcriptomics [PDF]
Neuron, 2002 In this issue of Neuron, report different patterns of 5-HT2C pre-mRNA editing in suicide victims, as compared to controls. Treatment of mice with fluoxetine alters the pattern of 5-HT2C transcript editing in the direction opposite that observed for suicide victims.
Steven J. Garlow
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Transcriptomics in ecotoxicology [PDF]
Analytical and Bioanalytical Chemistry, 2010 The emergence of analytical tools for high-throughput screening of biomolecules has revolutionized the way in which toxicologists explore the impact of chemicals or other stressors on organisms. One of the most developed and routinely applied high-throughput analysis approaches is transcriptomics, also often referred to as gene expression profiling ...
Danielle J. Madureira +5 more
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Archaea, 2010 DNA microarray technology allows for a quick and easy comparison of complete transcriptomes, resulting in improved molecular insight in fluctuations of gene expression. After emergence of the microarray technology about a decade ago, the technique has now matured and has become routine in many molecular biology laboratories.
Walther, J. +2 more
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mSystems, 2017 Archetypal pathogenic bacterial strains are often used to elucidate regulatory networks of an entire pathovar, which encompasses multiple lineages and phylogroups. With enteropathogenic Escherichia coli (EPEC) as a model system, Hazen and colleagues (mSystems 6:e00024-17, 2017, https://doi.org/10.1128 ...
Amy Platenkamp, Jay L. Mellies
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A practical, bioinformatic workflow system for large data sets generated by next-generation sequencing [PDF]
, 2010 Transcriptomics (at the level of single cells, tissues and/or whole organisms) underpins many fields of biomedical science, from understanding the basic cellular function in model organisms, to the elucidation of the biological events that govern the ...
Aaron R. Jex +95 more
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High-depth spatial transcriptome analysis by photo-isolation chemistry
Nature Communications, 2021 Spatial analysis of RNAseq data is important. Here the authors report a method for transcriptome profiling combined with photo-isolation chemistry to allow determination of expression profiles specifically from photo-irradiated regions of interest which ...
Mizuki Honda +7 more
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Single-cell and spatial transcriptomics: deciphering brain complexity in health and disease
Nature Reviews Neurology, 2023 High-throughput single-cell technologies enable multiple layers of molecular biology to be probed at the single-cell level. Single-cell transcriptomic atlases spanning multiple developmental stages have been generated with the aim of dissecting the ...
Monika Piwecka +2 more
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Cells, 2022 Background: Glioblastoma (GB) is a devastating primary brain malignancy. The recurrence of GB is inevitable despite the standard treatment of surgery, chemotherapy, and radiation, and the median survival is limited to around 15 months.
Francesca Lessi +10 more
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Nature Communications, 2023 Spatial transcriptomics technologies are used to profile transcriptomes while preserving spatial information, which enables high-resolution characterization of transcriptional patterns and reconstruction of tissue architecture.
Haoyang Li +9 more
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Scientific Reports, 2021 An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Ammarah Hami +6 more
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