Results 21 to 30 of about 320,395 (368)
HTLV-1 persistence and leukemogenesis: A game of hide-and-seek with the host immune system
Frontiers in Immunology, 2022 Human T-cell leukemia virus type 1 (HTLV-1), a retrovirus which mainly infects CD4+ T cells and causes adult T-cell leukemia/lymphoma (ATL), is primarily transmitted via direct cell-to-cell transmission.
Benjy J. Y. Tan +3 more
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mSystems, 2017 Archetypal pathogenic bacterial strains are often used to elucidate regulatory networks of an entire pathovar, which encompasses multiple lineages and phylogroups. With enteropathogenic Escherichia coli (EPEC) as a model system, Hazen and colleagues (mSystems 6:e00024-17, 2017, https://doi.org/10.1128 ...
Amy Platenkamp, Jay L. Mellies
openaire +3 more sources
Identification and characterization of a novel enhancer in the HTLV-1 proviral genome
Nature Communications, 2022 Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic virus with constantly active antisense transcription from the proviral genome. Here, Matsuo et al.
Misaki Matsuo +16 more
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Nature Communications, 2023 Spatial transcriptomics technologies are used to profile transcriptomes while preserving spatial information, which enables high-resolution characterization of transcriptional patterns and reconstruction of tissue architecture.
Haoyang Li +9 more
semanticscholar +1 more source
High-depth spatial transcriptome analysis by photo-isolation chemistry
Nature Communications, 2021 Spatial analysis of RNAseq data is important. Here the authors report a method for transcriptome profiling combined with photo-isolation chemistry to allow determination of expression profiles specifically from photo-irradiated regions of interest which ...
Mizuki Honda +7 more
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Single-cell and spatial transcriptomics: deciphering brain complexity in health and disease
Nature Reviews Neurology, 2023 High-throughput single-cell technologies enable multiple layers of molecular biology to be probed at the single-cell level. Single-cell transcriptomic atlases spanning multiple developmental stages have been generated with the aim of dissecting the ...
Monika Piwecka +2 more
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An introduction to spatial transcriptomics for biomedical research
Genome Medicine, 2022 Single-cell transcriptomics (scRNA-seq) has become essential for biomedical research over the past decade, particularly in developmental biology, cancer, immunology, and neuroscience.
Cameron G. Williams +4 more
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bioRxiv, 2023 Spatially resolved transcriptomics involves a set of emerging technologies that enable the transcriptomic profiling of tissues with the physical location of expressions. Although a variety of methods have been developed for data integration, most of them
Wei Liu +10 more
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Cells, 2022 Background: Glioblastoma (GB) is a devastating primary brain malignancy. The recurrence of GB is inevitable despite the standard treatment of surgery, chemotherapy, and radiation, and the median survival is limited to around 15 months.
Francesca Lessi +10 more
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Spatial transcriptomics of dorsal root ganglia identifies molecular signatures of human nociceptors
Science Translational Medicine, 2022 Nociceptors are specialized sensory neurons that detect damaging or potentially damaging stimuli and are found in the dorsal root ganglia (DRG) and trigeminal ganglia.
Diana Tavares-Ferreira +14 more
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