Results 51 to 60 of about 299,908 (313)
FabR regulates Salmonella biofilm formation via its direct target FabB [PDF]
, 2016 Background: Biofilm formation is an important survival strategy of Salmonella in all environments. By mutant screening, we showed a knock-out mutant of fabR, encoding a repressor of unsaturated fatty acid biosynthesis (UFA), to have impaired biofilm ...
De Coster, David +8 more
core +4 more sources
Advanced NanoBiomed Research, 2021 Despite their ubiquity in personal care products, the health implications of titanium dioxide (TiO2) nanomaterials (NMs) are under strenuous investigation for their potential as a carcinogen, whereas other evidence has shown links with premature ageing ...
Laura-Jayne A. Ellis +6 more
doaj +1 more source
F1000Research, 2021 Emerging studies demonstrate the ability of microRNAs (miRNAs) to activate genes via different mechanisms. Specifically, miRNAs may trigger an enhancer promoting chromatin remodelling in the enhancer region, thus activating the enhancer and its target ...
Anna Elizarova +3 more
doaj +1 more source
Standards and infrastructure for managing experimental metadata [PDF]
, 2009 *See also the "related presentation":http://precedings.nature.com/documents/3145/version/1* We present an infrastructure that leverages synergistic reporting standards and ontologies^1,2,3,4,5^ to create a common structured ...
Chris Taylor +7 more
core +2 more sources
Diatom Proteomics Reveals Unique Acclimation Strategies to Mitigate Fe Limitation [PDF]
, 2015 Phytoplankton growth rates are limited by the supply of iron (Fe) in approximately one third of the open ocean, with major implications for carbon dioxide sequestration and carbon (C) biogeochemistry.
Boyd, Philip W. +7 more
core +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Transcriptomic effects of the non-steroidal anti-inflammatory drug Ibuprofen in the marine bivalve Mytilus galloprovincialis Lam [PDF]
, 2016 The transcriptomic effects of Ibuprofen (IBU) in the digestive gland tissue of Mytilus galloprovincialis Lam. specimens exposed at low environmental concentrations (250 ng L-1) are presented. Using a 1.7 K feature cDNA microarray along with linear models
Amorim, Monica J. B. +3 more
core +1 more source
The acute phase reactant orosomucoid-2 directly promotes rheumatoid inflammation
Experimental and Molecular MedicineAcute phase proteins involved in chronic inflammatory diseases have not been systematically analyzed. Here, global proteome profiling of serum and urine revealed that orosomucoid-2 (ORM2), an acute phase reactant, was differentially expressed in ...
Ki-Myo Kim +7 more
doaj +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Reconstructing epigenomic dynamics through a single-cell multi-epigenome data integration framework
Nature CommunicationsTranscriptional regulation arises from the dynamic and combinatorial actions of multiple regulatory factors on genomic DNA. Although many epigenomic regulators have been identified, the precise order in which these factors accumulate at individual gene ...
Takeru Fujii +10 more
doaj +1 more source