Results 71 to 80 of about 3,038,700 (252)

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Chitosan-based transdermal drug delivery systems to overcome skin barrier functions [PDF]

, 2019
Transdermal drug delivery system has been developed or being developed to vanquish the downsides associated with conventional strategies as it avoids first pass hepatic metabolism, improved patient compliances, easy termination of therapy, possibility of
Nair, Syam S.
core   +1 more source

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

Advanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

Eutectogel with superior adhesion and high drug loading for transdermal delivery of loxoprofen against arthritis induced in rats

International Journal of Pharmaceutics: X
Transdermal drug delivery represents an important therapeutic approach for arthritis. However, conventional hydrogels for transdermal drug delivery face several challenges, including insufficient adhesion, low drug-loading capacity for hydrophobic drugs,
Yimeng Zhang, Man Li, Jiayue Zhang, Xinyue Zhang, Zhuopeng Du, Nanxi Zhao, Manli Wang, Zheng Luo   +7 more
doaj   +1 more source

Current Advancements in Transdermal Biosensing and Targeted Drug Delivery

Sensors, 2019
In this manuscript, recent advancements in the area of minimally-invasive transdermal biosensing and drug delivery are reviewed. The administration of therapeutic entities through the skin is complicated by the stratum corneum layer, which serves as a ...
Prem C. Pandey, Shubhangi Shukla, Shelby A. Skoog, Ryan D. Boehm, Roger J. Narayan   +4 more
doaj   +1 more source

Sustained Delivery of a Shingles Subunit Vaccine Overcomes Age‐Related Declines in Humoral and Cellular Immunity Relative to Shingrix

Advanced Science, EarlyView.
Sustained delivery of a shingles subunit vaccine from an injectable polymer–nanoparticle hydrogel enhanced the potency, durability, and breadth of immune responses in aged mice while minimizing inflammatory cytokine production and reactogenicity. This strategy decouples immunogenicity from reactogenicity and offers a promising approach to improve ...
Ye Eun Song, Jerry Yan, Ben S. Ou, Olivia M. Saouaf, Noah Eckman, E. A. Appel   +5 more
wiley   +1 more source

A C‐Nucleoside Analogue of Cordycepin With High Metabolic Stability and Potent Anti‐Psoriatic Activity via Microneedle Delivery

Advanced Science, EarlyView.
This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan, Xinyue Shao, Yuanchen Zhong, Xujie Sun, Lixuan Yin, Zongyan He, Tianqun Lang, Yuanchao Xie   +7 more
wiley   +1 more source

Transdermal Delivery of Ketoprofen for Osteoarthritis Treatment and Management: A Literature Review on Current Progression

Pharmaceutical Sciences and Research
Arthritis, a diverse spectrum of joint disorders, is characterized by chronic pain and inflammation. Osteoarthritis (OA), the most prevalent form, leads to disabling pain, functional limitations, and reduced mobility. Nonsteroidal anti-inflammatory drugs
Dwi Asih Ramadhani, Yahdiana Harahap, Erny Sagita, Kartika Citra Dewi Permata Sari , Rr. Kirana Andranilla , Jessica Trisina, Gabriella Frederika Punu   +6 more
doaj   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Ionic liquids self-assembled micelles for transdermal delivery: characterization, functions and applications

International Journal of Pharmaceutics: X
Ionic liquid (ILs) self-assembled micelles (ILs-SAMs) are promising and effective drug delivery systems, which combine the merits of ILs and micelles. Herein, the properties, assembly, functions, and treatments of ILs-SAMs in transdermal drug delivery ...
Ziqing Deng, Shuwei Tang, Mingjie Ou, Zhuxian Wang   +3 more
doaj   +1 more source