Mechanism of transdermal permeation promotion of lipophilic drugs by ethosomes. [PDF]
Int J Nanomedicine, 2017 Ethosomes can promote the penetration of lipophilic drugs into the skin, but the underlying mechanism is still unknown. The purpose of this study was to investigate the mechanism of transdermal permeation promotion of lipophilic drugs by ethosomes. The formulation of ethosomes was optimized using the Box-Behnken experimental design, in which Rhodamine ...
Yang L +5 more
europepmc +7 more sources
Effect of Ultrasound on Transdermal Permeation of Diclofenac [PDF]
European Journal of Inflammation, 2006 During the last two decades the effects of ultrasound on the transdermal permeability to a wide variety of drugs have been extensively investigated. There is still some uncertainty regarding the mechanisms involved in ultrasonic permeation enhancement, thus we investigated the effect of ultrasonic treatment on the transdermal permeation of the NSAID ...
Pieter van der Bijl +3 more
openalex +3 more sources
Mechanism investigation of ethosomes transdermal permeation. [PDF]
Int J Pharm X, 2019 Ethosomes are widely used to promote transdermal permeation of both lipophilic and hydrophilic drugs, but the mechanism of interaction between the ethosomes and the skin remains unclear. In this work, it was exploded with several technologies and facilities.
Niu XQ +10 more
europepmc +5 more sources
Transdermal permeation of curcumin promoted by choline geranate ionic liquid: Potential for the treatment of skin diseases [PDF]
Saudi Pharmaceutical Journal, 2022 The transdermal permeation of curcumin aided by choline and geranic acid ionic liquid (CAGE-IL) was addressed as a potential treatment for skin diseases.
Rodrigo Boscariol +4 more
doaj +2 more sources
Performance of Choline Geranate Deep Eutectic Solvent as Transdermal Permeation Enhancer: An In Vitro Skin Histological Study [PDF]
Pharmaceutics, 2021 In the present research work, we addressed the changes in skin by which deep eutectic solvents (DES) enhanced transdermal permeation of bioactive compounds and propose a rationale for this mechanism. Several studies showed that these unusual liquids were
Rodrigo Boscariol +6 more
doaj +2 more sources
Transdermal Permeation of Drugs in Various Animal Species. [PDF]
Pharmaceutics, 2017 Excised human skin is utilized for in vitro permeation experiments to evaluate the safety and effect of topically-applied drugs by measuring its skin permeation and concentration. However, ethical considerations are the major problem for using human skin to evaluate percutaneous absorption.
Todo H.
europepmc +7 more sources
Development of Novel Formulations to Enhance in Vivo Transdermal Permeation of Tocopherol [PDF]
Acta Pharmaceutica, 2014 Tocopherol represents a big challenge for transdermal permeation owing to its extreme hydrophobicity and large molecular mass. The aim of the present study was to develop alpha-tocopherol (T) topical formulations and evaluate their ex vivo and in vivo ...
Nada Aly H. +3 more
doaj +2 more sources
Transdermal Permeation and Anti-Inflammation Activities of Novel Sinomenine Derivatives [PDF]
Molecules, 2016 Sinomenine is extracted from Sinomenii caulis (a traditional Chinese medicine), and it is used as the active ingredient in rheumatic arthritis treatments. It has been used in clinical applications for decades.
Zi-Jian Zhao +3 more
doaj +2 more sources
Effect of Chemical Enhancers in Transdermal Permeation of Alfuzosin Hydrochloride [PDF]
ISRN Pharmaceutics, 2012 The objective of the present study is to explore the efficient chemical penetration enhancer among the various enhancers available in overcoming the stratum corneum barrier in transdermal delivery of Alfuzosin hydrochloride (AH). The different enhancers were incorporated in 2% Carbopol gel which was selected as a control and evaluated by in vitro ...
D Prasanthi, P K Lakshmi
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Novel chemical permeation enhancers for transdermal drug delivery
Asian Journal of Pharmaceutical Sciences, 2014 Transdermal drug delivery has been accepted as a potential non-invasive route of drug administration, with advantages of prolonged therapeutic action, decreased side effect, easy use and better patient compliance.
Yang Chen +4 more
doaj +3 more sources