Results 181 to 190 of about 88,006 (229)

Machine Learning-Driven Surrogate Modeling and Operating-Point Selection for a Microfluidic Diffusion-Membrane Platform for Transdermal Drug Delivery. [PDF]

Membranes (Basel)
Torabi T, Harasy MJ, Tahmoresnezhad J, Malekmohammadi S, Iulianelli A, Ghasemzadeh K.   +5 more
europepmc   +1 more source

Microstructural Characterization and In Vitro-In Vivo Evaluation of Drug Release and Permeation in Goupi Plaster. [PDF]

Pharmaceutics
Liu J, Guan T, Zhang A, Liu Y, Yang Z, Guan F, Li W, Wang Y.   +7 more
europepmc   +1 more source

Transferosomes as Drug Delivery Systems: Design Principles, Deformability, and Translational Challenges. [PDF]

Pharmaceuticals (Basel)
Nieves EA, Cotto MC, Márquez F.
europepmc   +1 more source

Mechanisms and therapeutic design of stimuli-responsive vesicular nanocarriers for melanoma. [PDF]

Int J Pharm X
Adarkar R, Dessai A, Ramesh MM, Lobo R, Tippavajhala VK, Subraya CK.   +5 more
europepmc   +1 more source

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Permeation Enhancers for Transdermal Drug Delivery

Drug Development and Industrial Pharmacy, 2000
The transdermal route has been recognized as one of the highly potential routes of systemic drug delivery and provides the advantage of avoidance of the first-pass effect, ease of use and withdrawal (in case of side effects), and better patient compliance.
V R Sinha
exaly   +3 more sources

Permeation-Enhancing Strategies for Transdermal Delivery of Cannabinoids

Cannabis & Cannabinoid Research, 2023
Introduction: This review aims to provide an overview of the advancements and status of clinical studies and potential permeation-enhancing strategies in the transdermal delivery of cannabinoids. Methods: A systematic and comprehensive
Atefeh Torabi, Frederikke Bahrt Madsen, Anne Ladegaard Skov   +2 more
openaire   +3 more sources

Transdermal permeation enhancement of N-trimethyl chitosan for testosterone

International Journal of Pharmaceutics, 2008
The aim of this study was to evaluate the transdermal permeation enhancement of N-trimethyl chitosan (TMC) with different degrees of quaternization (DQ). TMCs with DQ of 40 and 60% (TMC40 and TMC60) were synthesized and characterized by (1)H NMR. Testosterone (TS) used as an effective drug, four different gels were prepared without enhancer, with 5 ...
Mian Zhang
exaly   +3 more sources

Homoharringtonine is a transdermal granular permeation enhancer

Biochemical and Biophysical Research Communications, 2022
Although modulation of claudin-1-based tight junction (TJ) in stratum granulosum is an option for transdermal absorption of drugs, granular permeation enhancers have never been developed. We previously found that homoharringtonine (HHT), a natural alkanoid, weakened intestinal epithelial barrier with changing expression and cellular localization of TJ ...
Akihiro, Watari, Kana, Fujiwara, Kiyohito, Yagi, Keisuke, Tachibana, Takeshi, Katsurada, Akira, Myoui, Masuo, Kondoh   +6 more
openaire   +2 more sources

In Vitro Studies on Transdermal Permeation of Butorphanol

Drug Development and Industrial Pharmacy, 2007
The influence of the donor vehicles pH and the addition of laurocapram or transkarbam 12 as permeation enhancers on the transdermal permeation of butorphanol through human skin were examined with the aim of finding out about its possible use in the transdermal delivery system.
Michal, Svozil, Pavel, Dolezal, Alexander, Hrabálek, Pavel, Mericka   +3 more
openaire   +2 more sources

Physicochemical aspects of transdermal permeation

Journal of Controlled Release, 1987
Abstract The nature and state of lipids are often important regulators in many membrane functions and properties. Current studies probe the physicochemical aspects of the enhanced permeabilities of lipophilic solutes through hairless mouse stratum corneum.
K. Knutson, S.L. Krill, W.J. Lambert, W.I. Higuchi   +3 more
openaire   +1 more source