Electret Enhances Transdermal Drug Permeation
Biological and Pharmaceutical Bulletin, 2008 Electrets are polymeric discs that carry semi permanent electrostatic charge. These provide electrostatic potentials in the range of 500 to 3,000 V. In the current work, the effect of electret exposure on the skin permeability was investigated. Transdermal transport studies were carried out across porcine epidermis in Franz diffusion cells.
Narasimha Sathyanarayana, Narasimha Sathyanarayana Murthy +2 more
openaire +2 more sources
Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]
, 2014 Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G.
core +1 more source
Vesicular systems for delivering conventional small organic molecules and larger macromolecules to and through human skin [PDF]
, 2009 The history of using vesicular systems for drug delivery to and through skin started nearly three decades ago with a study utilizing phospholipid liposomes to improve skin deposition and reduce systemic effects of triamcinolone acetonide.
El Maghraby, Gamal M. +1 more
core +1 more source
Influence of the Component Excipients on the Quality and Functionality of a Transdermal Film Formulation [PDF]
, 2015 The influence of formulation variables, i.e., a hydrophilic polymer (Methocel® E15) and a film-forming polymer (Eudragit® RL 100 and Eudragit® RS 100), on the physicochemical and functional properties of a transdermal film formulation was assessed ...
Atram, Sandip C. +5 more
core +1 more source
N-Alkylmorpholines: Potent Dermal and Transdermal Skin Permeation Enhancers [PDF]
Pharmaceutics, 2021 Transdermal drug delivery is an attractive non-invasive method offering numerous advantages over the conventional routes of administration. The main obstacle to drug transport is, however, the powerful skin barrier that needs to be modulated, for example, by transdermal permeation enhancers.
Kristýna Dvořáková +3 more
openaire +3 more sources
A Note on the Trandermal Delivery of Clenbuterol [PDF]
, 1992 A modified diffusion/compartmental model has been used to simulate the transdermal uptake of clenbuterol from a matrix-type delivery device. The application of a fresh device every 7 days was found to produce a pseudo-steady state drug plasma profile ...
Göpferich, Achim, Lee, Geoffrey
core +1 more source
The use of heat and chemical penetration enhancers to increase the follicular delivery of erythromycin to the skin [PDF]
, 2019 Copyright © 2019. Published by Elsevier B.V.The effect of heat on the follicular absorption of drugs into the skin has not previously been investigated.
Akomeah +42 more
core +2 more sources
Permeation enhancer strategies in transdermal drug delivery
Drug Delivery, 2014 Today, ∼74% of drugs are taken orally and are not found to be as effective as desired. To improve such characteristics, transdermal drug delivery was brought to existence. This delivery system is capable of transporting the drug or macromolecules painlessly through skin into the blood circulation at fixed rate.
Harneet, Marwah +3 more
openaire +2 more sources
Transdermal delivery of ibuprofen utilizing a novel solvent free pressure sensitive adhesive (PSA) : TEPI® technology [PDF]
, 2017 Purpose The main objective of this present study was the investigation of potential novel transdermal patch technology (TEPI®) delivering ibuprofen as the active pharmaceutical ingredient (API) using a novel poly(ether-urethane)-silicone crosslinked ...
Haddleton, David M. +3 more
core +1 more source
A systematic approach to the formulation of anti-onychomycotic nail patches [PDF]
, 2018 Nail patches have a potential role as drug carriers for the topical treatment of nail diseases such as onychomycosis, a common condition. O ur aim was therefore to develop a systematic and novel appr oach to the formulat ion of a simple drug -in-adhesive
Charalambides, MN +5 more
core +1 more source