Results 21 to 30 of about 17,319 (246)
A two-phase two-layer model for transdermal drug delivery and percutaneous absorption
, 2014 One of the promising frontiers of bioengineering is the controlled release of a therapeuticdrug from a vehicle across the skin (transdermal drug delivery).
de Monte, Filippo, Pontrelli, Giuseppe
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Current and evolving approaches for improving the oral permeability of BCS Class III or analogous molecules [PDF]
, 2016 The Biopharmaceutics Classification System (BCS) classifies pharmaceutical compounds based on their aqueous solubility and intestinal permeability. The BCS Class III compounds are hydrophilic molecules (high aqueous solubility) with low permeability ...
Dave, Vivek S +4 more
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Drug crystallization – implications for topical and transdermal delivery [PDF]
, 2016 INTRODUCTION: Crystallization of actives in skin following topical application was suggested by studies in the 1950s and 1960s but is poorly understood.
Hadgraft, J, Lane, ME
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Advanced Functional Materials, EarlyView.A flexible hybrid patch integrating a robust cold atmospheric plasma (CAP) system with a high‐power, ultrathin bio‐OLED was developed to enable synergistic wound healing. This multimodal therapy, combining plasma and photodynamic treatment, enhanced angiogenesis, cell proliferation, and collagen deposition, demonstrating superior in vivo efficacy and ...
Jun‐Yeop Song +11 more
wiley +1 more source
A multicenter, open-label, long-term safety and tolerability study of DFN-02, an intranasal spray of sumatriptan 10 mg plus permeation enhancer DDM, for the acute treatment of episodic migraine. [PDF]
, 2017 BackgroundDFN-02 is a novel intranasal spray formulation composed of sumatriptan 10 mg and a permeation-enhancing excipient comprised of 0.2% 1-O-n-Dodecyl-β-D-Maltopyranoside (DDM).
Allenby, Kent +5 more
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Effect of Microneedle Type on Transdermal Permeation of Rizatriptan [PDF]
AAPS PharmSciTech, 2017 The present study was aimed to investigate the effect of salient microneedle (MN) geometry parameters like length, density, shape and type on transdermal permeation of rizatriptan (RIZ). Studies were carried out using two types of MN devices viz. AdminPatch® arrays (ADM) (0.6, 0.9, 1.2 and 1.5 mm lengths) and laboratory-fabricated polymeric MNs (PMs ...
Chandrateja, Uppuluri +7 more
openaire +2 more sources
Advanced Healthcare Materials, EarlyView.Injectable POEGMA‐DA hydrogels, dual‐crosslinked via dopamine self‐polymerization and dynamic hydrazone bonds, provide a safer alternative to invasive wound closure methods and toxic bioadhesives. Mimicking skin‐like mechanics, they achieve effective tissue adhesion for acute dermal wounds, supporting improved healing outcomes, including reducing ...
Gurpreet Kaur Randhawa +6 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Next‐Generation Psoriasis Therapy – With advanced dendrimer‐based formulations, this study paves the way for highly effective, skin‐permeable treatments. Encapsulated in fluid catanionic vesicles, IMD‐006 and its analogues show promising anti‐psoriatic effects offering a targeted, non‐invasive approach to managing chronic skin inflammation.
Ranime Jebbawi +10 more
wiley +1 more source
N-alkylamides : from plant to brain [PDF]
, 2014 Background: Plant N-alkylamides (NAAs) are bio-active compounds with a broad functional spectrum. In order to reach their pharmacodynamic targets, they have to overcome several barriers of the body in the absorption phase.
De Spiegeleer, Bart +6 more
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Dermic diffusion and stratum corneum: a state of the art review of mathematical models [PDF]
, 2014 Transdermal biotechnologies are an ever increasing field of interest, due to the medical and pharmaceutical applications that they underlie. There are several mathematical models at use that permit a more inclusive vision of pure experimental data and ...
Cordeiro, M. Natália D. S. +5 more
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