Results 31 to 40 of about 6,917 (245)
Temperature influencing permeation pattern of alfuzosin: An investigation using DoE
Medicina, 2015 Background and objective: There has been relatively little investigation of the effect of temperature on skin permeation compared to other methods of penetration enhancement.
Satyanarayan Pattnaik +4 more
doaj +1 more source
Pharmaceutics, 2023 Retinoid-based drugs, while effective, are associated with systemic toxicity. Topical alternatives offer a safer option, and tazarotene, a third-generation synthetic retinoid, holds promise.
Helena Hamzehpour +5 more
doaj +1 more source
In vitro transdermal permeation of fenoterol hydrobromide
Journal of Advanced Research, 2012 AbstractThe aim of this study was to determine if transdermal penetration of fenoterol, a β-agonist drug, could be enhanced and controlled by formulation modification and formulation of transdermal patches. Pre-formulation studies were performed to determine the feasibility of a transdermal dosage form of fenoterol.
Hossein Zia +4 more
openaire +4 more sources
Non-invasive Transdermal Delivery of Human Insulin Using Ionic Liquids: In vitro Studies
Frontiers in Pharmacology, 2020 In this research project, synthesis and characterization of ionic liquids and their subsequent utilization as facilitators of transdermal delivery of human insulin was pursued.
Ludmilla R. Jorge +11 more
doaj +1 more source
Effect of Microneedle Type on Transdermal Permeation of Rizatriptan [PDF]
AAPS PharmSciTech, 2017 The present study was aimed to investigate the effect of salient microneedle (MN) geometry parameters like length, density, shape and type on transdermal permeation of rizatriptan (RIZ). Studies were carried out using two types of MN devices viz. AdminPatch® arrays (ADM) (0.6, 0.9, 1.2 and 1.5 mm lengths) and laboratory-fabricated polymeric MNs (PMs ...
Diganta Bhusan Das +7 more
openaire +3 more sources
Permeation enhancer strategies in transdermal drug delivery [PDF]
Drug Delivery, 2014 Today, ∼74% of drugs are taken orally and are not found to be as effective as desired. To improve such characteristics, transdermal drug delivery was brought to existence. This delivery system is capable of transporting the drug or macromolecules painlessly through skin into the blood circulation at fixed rate.
Amit K. Goyal +3 more
openaire +2 more sources
Pharmaceutics, 2021 The exponentially mounting cases of herpes simplex virus infection or cold sores have become a serious global concern. Acyclovir (ACV) and garlic oil (GO)-loaded lipid nanocarrier could be a promising therapeutic approach in alleviating cold sores, as ...
Alshaimaa M. Almehmady, Sarah A. Ali
doaj +1 more source
Effect of microneedles on transdermal permeation enhancement of amlodipine [PDF]
Drug Delivery and Translational Research, 2017 The present study aimed to investigate the effect of microneedle (MN) geometry parameters like length, density, shape and type on transdermal permeation enhancement of amlodipine (AMLO). Two types of MN devices viz. AdminPatch® arrays (ADM) (0.6, 1.2 and 1.5 mm lengths) and laboratory-fabricated polymeric MNs (PM) of 0.6 mm length were employed. In the
Diganta Bhusan Das +6 more
openaire +3 more sources
Asian Journal of Pharmaceutical Sciences, 2023 Overlook of chiral consideration in transdermal drug delivery increases administrated dose and risk of side effects, decreasing therapeutical effects. To improve the transdermal delivery efficiency of eutomer, this work focused on investigating the law ...
Yang Zhang +9 more
doaj
Optimization and Characterization of Chitosan Films for Transdermal Delivery of Ondansetron
Molecules, 2013 The aim of this study was to develop novel transdermal films of ondansetron HCl with high molecular weight chitosan as matrix polymer and 2-(2-ethoxy-ethoxy) ethanol (Transcutol®) as plasticizer. In this context, firstly the physicochemical properties of
Yıldız Özsoy +3 more
doaj +1 more source