Results 41 to 50 of about 93 (93)

Deep Eutectic Solvents in Polymeric Drug Carriers: Insights into Release Behavior and Functional Integration

ChemistryOpen, EarlyView.
Incorporating deep eutectic solvents into polymer‐based drug delivery systems (DDS) offers a sustainable route to enhance solubility, modify drug release, and create dual‐function carriers. This review explores how DES influence polymer structures and DDS performance, highlighting future prospects in personalized, responsive pharmaceutical technologies.
Nining Nining, Yoga Windhu Wardhana, Taofik Rusdiana, Hariyanti Hariyanti   +3 more
wiley   +1 more source

Development of phytotherapeutic nanoformulation containing Gypsophila eriocalyx and its evaluation as a candidate formulation for osteoporosis treatment on human bone marrow stem cells

Phytochemical Analysis, EarlyView.
Abstract Introduction Osteoporosis, one of the common bone diseases, manifests itself as a decrease in bone mass. Recently, the use of medicinal plants in the search for effective and low‐toxicity therapeutics for the prevention or treatment of osteoporosis has become a trending topic.
Sibel Kaymak, Ozan Baris Kurtur, Bahar Gok, Yasemin Budama‐Kilinc, Serda Kecel‐Gunduz, Ebru Özdemir Nath, Murat Kartal   +6 more
wiley   +1 more source

Nanoparticle‐Based Tetracycline Delivery Systems: Advancing Therapeutic Effectiveness and Tackling Antibiotic Resistance

Particle &Particle Systems Characterization, EarlyView.
This review explores improved tetracycline (TCN) delivery via polymer‐based nanocarriers to enhance solubility, stability, and targeted release. It also covers stimuli‐responsive systems, triggered by pH, enzymes, or reactive oxygen species (ROS), and co‐delivery approaches that increase therapeutic efficacy in cancer and inflammatory diseases ...
Mahsa Molaei Nasr, Mehrab Pourmadadi, Fatemeh Yazdian, Hamid Rashedi, Abbas Rahdar, M. Ali Aboudzadeh   +5 more
wiley   +1 more source

The Association Between Clinically Diagnosed Neonatal Jaundice and Autism: A Swedish Register‐Based Cohort Study

Acta Paediatrica, EarlyView.
ABSTRACT Aim Neonatal jaundice may increase the likelihood of autism through its influence on neurodevelopment. We assessed whether neonatal jaundice increases the risk for autism while accounting for confounding of perinatal risk factors. Method We used a population‐based cohort of 1 669 830 individuals born in Sweden between 1992 and 2010 ...
Aleksandra Kanina, Zhou Li, Mina Rosenqvist, Agnieszka Butwicka, Henrik Larsson, Stefan Johansson, Márta K. Radó, Miriam I. Martini, Mark J. Taylor   +8 more
wiley   +1 more source

Anti‐inflammatory effects of physical stimuli: The central role of networks in shaping the future of pharmacological research

British Journal of Pharmacology, EarlyView.
Addressing complexity in the study of life sciences through Systems Biology and Systems Medicine has been transformative, making Systems Pharmacology the next logical step. In this review, we focus on physical stimuli, whose potential in pharmacology has been neglected, despite demonstrated therapeutic properties.
Veronica Paparozzi, Reyhaneh Hooshmandabbasi, Alessandro Ravoni, Ying Ma, Luigi Manni, Timothy J. Koh, Caroline Maake, Tiziana Guarnieri, Darong Lai, Vitalii Zablotskii, Christine Nardini   +10 more
wiley   +1 more source

Moisturising Gloves as a Solution for Occupational Skin Health: Advances and Challenges

Contact Dermatitis, EarlyView.
This review highlights moisturising gloves as a promising strategy to combat glove‐induced skin dryness in occupational settings. It outlines key design considerations, current technologies and unresolved research gaps that must be addressed to enable their practical adoption for preventing occupational skin diseases.
Sher Wei How, Janarthanan Supramaniam, Thet Thet Htar, Bey Fen Leo, Sivakumar Manickam, Bey Hing Goh, Siah Ying Tang   +6 more
wiley   +1 more source

A Screening of Permeation Enhancers for Transdermal Delivery of Propofol

Journal of Bioequivalence & Bioavailability, 2018
Propofol is a highly lipophilic anesthetic drug used to induce sedation, predictable amnesia and anxiolysis. In this project, several permeation enhancers were screened to improve the permeation of propofol across the porcine full thickness skin. The screening studies of permeation enhancers was performed in two phases.
openaire   +2 more sources

PEG‐23 glyceryl distearate, a multifunctional skin‐supporting material, upregulates the expression of factors associated with epidermal barrier and hydration

International Journal of Cosmetic Science, EarlyView.
Polyethylene glycol‐23 glyceryl distearate (GDS‐23) forms niosomes and penetrates the skin. Our results suggest that the pharmacological effects following dermal penetration of GDS‐23 may enhance skin homeostasis by improving barrier function and moisture retention.
Tatsuro Miyoshi, Brian C. Keller, Sui Nakagawa, Takashi Ashino, Satoshi Numazawa   +4 more
wiley   +1 more source

EuroSCORE II: Current limitations and physiological gaps in risk stratification

Experimental Physiology, EarlyView.
Abstract Risk stratification remains critical in cardiac surgery, enabling clinicians to predict adverse outcomes and guide perioperative management. The European System for Cardiac Operative Risk Evaluation (EuroSCORE) II, introduced in 2011, incorporates 18 key variables to provide an evidence‐based approach to risk assessment.
Jing Yong Ng, Eu Fon Tan, Marsioleda Kemberi, Eduardo Urgesi, Matti Jubouri, Damian M. Bailey, Mohamad Bashir, Wael I. Awad   +7 more
wiley   +1 more source

Management Strategies for Refractory Esophageal Varices

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Refractory esophageal varices that are difficult to control or unresponsive to endoscopic treatment remain a major clinical challenge in the management of portal hypertension. This review provides a comprehensive overview of treatment strategies for these cases, along with a comparative analysis of the American Association for the Study of ...
Keita Maki, Hiroaki Haga, Yoshiyuki Ueno
wiley   +1 more source