Results 61 to 70 of about 17,319 (246)

Controlled-release of opioids for improved pain management [PDF]

, 2016
The adequate treatment of pain remains one of the major medical challenges. Morphine and other opioid drugs are most commonly used to counteract moderate to severe pain, but they are also increasingly accessed by patients with chronic non-malignant pain.
Ballet, Steven, De Baerdemaeker, Andy, Hoogenboom, Richard, Madder, Annemieke, Martin, Charlotte, Poelaert, Jan   +5 more
core   +1 more source

ROS‐Responsive Wedelolactone Hydrogel Promotes Intervertebral Disc Repair by Disrupting the NF‐κB–LCN2 Inflammatory Feedback Loop

Advanced Science, EarlyView.
A mechanically robust, ROS‐responsive hydrogel is engineered to treat intervertebral disc degeneration by targeting the NF‐κB–LCN2 inflammatory feedback loop. By delivering wedelolactone specifically within oxidative niches, this system disrupts macrophage–disc cell crosstalk.
Zimei Wu, Yan Xu, Lang Qin, Zemin Ling, Yingjie Mai, Xiong Tian Guo, Jiajia Chen, Leping Yan, Lin Wang, Liming Bian, Fuxin Wei   +10 more
wiley   +1 more source

Pengaruh Kombinasi Asam Oleat Dan Minyak Atsiri Daun Cengkeh (Syzygium Aromaticum L.) Sebagai Permeation Enhancer Terhadap Karakter Fisik Dan Pelepasan Ketoprofen Dari Matriks Patch Transdermal [PDF]

, 2015
Ketoprofen adalah obat antiinflamasi non-steroid yang dapat menimbulkan iritasi pada saluran gastrointestinal, sehingga diperlukan jalur pemberian alternatif yaitu dengan patch transdermal.
I, S. E. (Setyawan), K, B. D. (Budiputra), S, G. I. (Guna)   +2 more
core  

Fucoxanthin-Containing Cream Prevents Epidermal Hyperplasia and UVB-Induced Skin Erythema in Mice [PDF]

, 2018
Microalgae represent a source of bio-active compounds such as carotenoids with potent anti-inflammatory and antioxidant properties. We aimed to investigate the effects of fucoxanthin (FX) in both in vitro and in vivo skin models.
Cózar Bernal, María José, González Rodríguez, María Luisa, Motilva Sánchez, Virginia, Rabasco Álvarez, Antonio María, Rodríguez Luna, Azahara María, Talero Barrientos, Elena Mª, Ávila Román, Francisco Javier   +6 more
core   +1 more source

Versatile DNA Hydrogel‐Mediated Delivery of Ginsenoside‐Encapsulated Small Extracellular Vesicles to Boost Diabetic Wound Repair

Advanced Science, EarlyView.
This study presents a DNA hydrogel‐mediated delivery system, in which ginsenoside (GS) molecules are incorporated into small extracellular vesicles (sEV) secreted by mesenchymal stem cells (MSCs) and the formed complexes are then anchored in DNA hydrogels via aptamer‐CD63 affinity as “GS/sEV@DNAgels”, to improve diabetic wound repair.
Jianming Xing, Shuangyang Li, Yuning Wang, Xushuang Jia, Ruiting Lin, Xintong Liu, Dongxu Wang, Ning Cui, Peng Ji, Jiaqi Chen, Shengnian Wang, Guangzhe Li, Ye Teng, Da Liu, Ye Jin   +14 more
wiley   +1 more source

Učinci adheziva osjetljivih na tlak i kemijskih promotora na permeaciju fentanila kroz kožu štakora [PDF]

, 2006
Drug-in-adhesive patches (DIAPs) of fentanyl were formulated using various pressure sensitive adhesives (PSAs) and various chemical permeation enhancers (CPEs).
AMIR MEHDIZADEH, MOHAMMAD HOSSAIN GHAHREMANI, MOHAMMAD REZA ROUINI, TAYEBEH TOLIYAT   +3 more
core   +1 more source

Application of the Aqueous Porous Pathway Model to Quantify the Effect of Sodium Lauryl Sulfate on Ultrasound-Induced Skin Structural Perturbation [PDF]

, 2010
This study investigated the effect of sodium lauryl sulfate (SLS) on skin structural perturbation when utilized simultaneously with low-frequency sonophoresis (LFS).
Baris E. Polat, Becker, Cua, Dahlan, Daniel Blankschtein, Dechadilok, Edwards, Farinha, Jennifer E. Seto, Johnson, Johnson, Karande, Kasting, Kasting, Kushner, Kushner, Kushner, Kushner, Lavon, Levy, Mitragotri, Mitragotri, Mitragotri, Mitragotri, Mitragotri, Mitragotri, Paliwal, Polat, Robert Langer, Rosell, Seto, Tang, Tang, Tang, Tezel, Tezel   +35 more
core   +1 more source

Beyond Silicon: Toward Sustainable, NIR‐II, and Conformable Organic Photodiodes

Advanced Energy Materials, EarlyView.
In this perspective, a strategic shift in organic photodetector (OPD) research is proposed: instead of the incremental advances in silicon's stronghold arena, the most impactful future for OPDs lies in addressing silicon's intrinsic limitations, i.e., detection in the longer wavelength range above silicon's coverage (>1100 nm, termed as near infrared ...
Hrisheekesh Thachoth Chandran, Jiaming Huang, Hao Xia, Rakesh Rajendran Nair, Shen Xing, Gang Li, Karl Leo, Johannes Benduhn   +7 more
wiley   +1 more source

Pengaruh Kombinasi Asam Oleat dan Minyak Atsiri Bunga Kamboja Cendana (Plumeria Alba) sebagai Permeation Enhancer terhadap Karakter Fisik dan Pelepasan Ketoprofen dari Matriks Patch Transdermal [PDF]

, 2015
Ketoprofen adalah obat antiinflamasi non-steroid yang dapat menimbulkan iritasi pada saluran gastrointestinal, sehingga diperlukan jalur pemberian alternatif yaitu dengan patch transdermal.
Budiputra, D. K. (D), Setyawan, E. I. (E), Triani, N. A. (N)   +2 more
core  

Deformable Nanovesicles Synthesized through an Adaptable Microfluidic Platform for Enhanced Localized Transdermal Drug Delivery. [PDF]

, 2017
Phospholipid-based deformable nanovesicles (DNVs) that have flexibility in shape offer an adaptable and facile method to encapsulate diverse classes of therapeutics and facilitate localized transdermal delivery while minimizing systemic exposure. Here we
Alam, Mohammad Parvez, Campagna, Jesus, Hokugo, Akishige, John, Varghese, Nishimura, Ichiro, Sharma, Shivani, Spilman, Patricia, Subbiah, Naren   +7 more
core   +2 more sources