Results 1 to 10 of about 554,940 (322)
G-CSF augments the neuroprotective effect of conditioned medium of dental pulp stem cells against hypoxic neural injury in SH-SY5Y cells [PDF]
Iranian Journal of Basic Medical Sciences, 2021 Objective(s): Dental pulp stem cells (DPSCs) can differentiate into functional neurons and have the potential for cell therapy in neurological diseases.
Farahnaz Ahmadi +4 more
doaj +1 more source
Inhibition of Small-Conductance, Ca2+-Activated K+ Current by Ondansetron
Frontiers in Pharmacology, 2021 Background: Small-conductance Ca2+-activated K+ channels (SK channels) have been proposed as antiarrhythmic targets for the treatment of atrial fibrillation.
Shuai Guo +4 more
doaj +1 more source
Suicide-Gene Transfection of Tumor-tropic Placental Stem Cells employing Ultrasound-Responsive Nanoparticles [PDF]
Acta Biomaterialia. 83, 372-378 (2018), 2021 A Trojan-horse strategy for cancer therapy employing tumor-tropic mesenchymal stem cells transfected with a non-viral nanovector is here presented. In this sense, ultrasound-responsive mesoporous silica nanoparticles were coated with a polycation (using two different molecular weights), providing them with gene transfection capabilities that were ...
arxiv +1 more source
Headgroup modification of cholesterol-based cationic lipids: Synthesis, transfection efficiency evaluation, and serum compatibility [PDF]
Songklanakarin Journal of Science and Technology (SJST), 2020 There were two objectives for this study. First, it focused on eight lipids having cholesterol as hydrophobic tails, carbamate linkers, and different polar headgroups.
Chopaka Thongbamrer +9 more
doaj +1 more source
Chinese Journal of Contemporary Neurology and Neurosurgery, 2021 Objective To investigate the anti⁃tumoral effect of ACT001, a novel antitumor compound, on the nuclear factor⁃κB (NF⁃κB) pathway and programmed cell death protein ligand 1 (PDL1) expression in U87 glioblastoma cell line.
ZHANG Jin⁃hao +9 more
doaj +1 more source
Frontiers in Genome Editing, 2021 Field cress (Lepidium campestre) is a potential oilseed crop that has been under domestication in recent decades. CRISPR/Cas9 is a powerful tool for rapid trait improvement and gene characterization and for generating transgene-free mutants using ...
Sjur Sandgrind +4 more
doaj +1 more source
Annexin A7 and Its Related Protein Suppressor of Death Domains Regulates Migration and Proliferation of Hca-P Cells [PDF]
Cell Journal, 2023 Objective: This study was to investigate whether annexin A7 (AnnexinA7, ANXA7) and its co-related protein tumor celldeath domain silencer [suppressor of death domains (SODD)] regulates the migratory phenotype of liver cancer cells.Materials and Methods ...
Shaoqing Wang +5 more
doaj +1 more source
Infectious viruses from transfected SARS-CoV-2 genomic RNA
Frontiers in Bioengineering and Biotechnology, 2023 SARS-CoV-2 emerged at the end of 2019, and like other novel pathogens causing severe symptoms, WHO recommended heightened biosafety measures for laboratories working with the virus.
Elina Väisänen +7 more
doaj +1 more source
Cationic lipid-mediated intracellular delivery of antibodies into live cells
BioTechniques, 2008 The ability to introduce antibodies to live cells opens new insights to a wide range of applications, such as protein intracellular trafficking studies, protein interference studies with blocking antibodies, and live immunolabeling or protein ...
Claire O. Weill +2 more
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2013 RNA interference (RNAi) is a major tool for basic and applied investigations. However, obtaining RNAi data that have physiological significance requires investigation of regulations and therapeutic strategies in appropriate in vivo settings.
Sylvie Remaud +11 more
doaj +1 more source