Results 11 to 20 of about 686,707 (295)
Central Asian Journal of Medical Sciences, 2016 Objectives: Chronic neutrophilic leukemia (CNL) is a rare, but distinct, entity within myeloproliferative neoplasms, characterized by splenomegaly, sustained mature neutrophilia, and absence of the Philadelphia chromosome. In 2013, oncogenic mutations in
Otgonbat Altangerel +2 more
doaj +1 more source
WDR7 up-regulation upon knocking down of neighboring non-coding RNA using siRNAs encapsulated in polyamidoamine dendrimers [PDF]
Iranian Journal of Basic Medical Sciences, 2019 Objective(s): Breast cancer is the second leading cause of cancer death in females. Understanding molecular mechanisms in cancer cells compared with normal cells is crucial for diagnostic and therapeutic strategies. Long intergenic non-protein coding RNA,
Sara Kor +4 more
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Pharmaceutics, 2022 Gene transfer into primary immune cells as well as into cell lines is essential for scientific and therapeutical applications. One of the methods used for gene transfer is electroporation (EP).
Eivina Radzevičiūtė +4 more
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Molecules, 2023 Poly(amidoamine) (PAMAM) dendrimers have attracted considerable attention in the field of gene therapy due to their flexibility in introducing different functional moieties and reduced toxicity at low generations.
Seongyeon Kim +3 more
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Laser-induced breakdown of an optically trapped gold nanoparticle for single cell transfection [PDF]
, 2013 The cell selective introduction of therapeutic agents remains a challenging problem. Here we demonstrate spatially controlled cavitation instigated by laser-induced breakdown of an optically trapped single gold nanoparticle of diameter 100 nm. The energy
Gunn-Moore, Frank J +10 more
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Optical transfection and injection techniques applied to mammalian and embryonic cells [PDF]
, 2012 The delivery of biomolecules into living cells is an important methodology in cell and molecular biology. Optical methods using lasers are attractive tools for such application.
Torres, Maria Leilani
core +2 more sources
mSphere, 2020 Double-stranded RNA (dsRNA) is the hallmark of many viral infections. dsRNA is produced either by RNA viruses during replication or by DNA viruses upon convergent transcription.
Olivier Petitjean +4 more
doaj +1 more source
In Vitro Evaluation of a Nanoparticle-Based mRNA Delivery System for Cells in the Joint
Biomedicines, 2021 Biodegradable and bioresponsive polymer-based nanoparticles (NPs) can be used for oligonucleotide delivery, making them a promising candidate for mRNA-based therapeutics.
Lisa Sturm +10 more
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Marine Drugs, 2023 The determination of the protein’s intracellular localization is essential for understanding its biological function. Protein localization studies are mainly performed on primary and secondary vertebrate cell lines for which most protocols have been ...
Kristina Dominko +6 more
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Generating Recombinant Antibodies to Membrane Proteins through Phage Display
Antibodies, 2016 One of the most important classes of proteins in terms of drug targets is cell surface membrane proteins, and yet it is a challenging set of proteins for generating high-quality affinity reagents.
Renhua Huang +4 more
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