Results 11 to 20 of about 692,115 (252)
A Mechanistic Dissection of Polyethylenimine Mediated Transfection of Chinese Hamster Ovary Cells [PDF]
, 2013 Biopharmaceutical production through transient gene expression (TGE) is used within industry for the rapid supply of product for early stage testing.
Mozley, O L
core +6 more sources
Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter [PDF]
FEBS Open BioThis minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Beccalli M, Bona B, Baldelli Bombelli F.
europepmc +2 more sources
Tailoring optical fibers for cell transfection [PDF]
, 2012 Optical transfection is a promising technique for the delivery of foreign genetic material into cells by transiently changing the permeability of the cell membrane.
Ma, Nan
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Laser-induced breakdown of an optically trapped gold nanoparticle for single cell transfection [PDF]
, 2013 The cell selective introduction of therapeutic agents remains a challenging problem. Here we demonstrate spatially controlled cavitation instigated by laser-induced breakdown of an optically trapped single gold nanoparticle of diameter 100 nm. The energy
Gunn-Moore, Frank J +12 more
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Optical sorting and photo-transfection of mammalian cells [PDF]
, 2010 Recently, laser light sources of different regimes have emerged as an essential tool in the biophotonics research area. Classic applications include, for example: manipulating single cells and their subcellular organelles, sorting cells in microfluidic ...
Mthunzi, Patience
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In Vitro Evaluation of a Nanoparticle-Based mRNA Delivery System for Cells in the Joint
Biomedicines, 2021 Biodegradable and bioresponsive polymer-based nanoparticles (NPs) can be used for oligonucleotide delivery, making them a promising candidate for mRNA-based therapeutics.
Lisa Sturm +10 more
doaj +1 more source
mSphere, 2020 Double-stranded RNA (dsRNA) is the hallmark of many viral infections. dsRNA is produced either by RNA viruses during replication or by DNA viruses upon convergent transcription.
Olivier Petitjean +4 more
doaj +1 more source
Marine Drugs, 2023 The determination of the protein’s intracellular localization is essential for understanding its biological function. Protein localization studies are mainly performed on primary and secondary vertebrate cell lines for which most protocols have been ...
Kristina Dominko +6 more
doaj +1 more source
Generating Recombinant Antibodies to Membrane Proteins through Phage Display
Antibodies, 2016 One of the most important classes of proteins in terms of drug targets is cell surface membrane proteins, and yet it is a challenging set of proteins for generating high-quality affinity reagents.
Renhua Huang +4 more
doaj +1 more source
Optical transfection and injection techniques applied to mammalian and embryonic cells [PDF]
, 2012 The delivery of biomolecules into living cells is an important methodology in cell and molecular biology. Optical methods using lasers are attractive tools for such application.
Torres, Maria Leilani
core +2 more sources