Results 11 to 20 of about 932,327 (388)

Protamine-Based Strategies for RNA Transfection

open access: yesPharmaceutics, 2021
Protamine is a natural cationic peptide mixture mostly known as a drug for the neutralization of heparin and as a compound in formulations of slow-release insulin.
Natalia Teresa Jarzebska   +4 more
doaj   +2 more sources

G-CSF augments the neuroprotective effect of conditioned medium of dental pulp stem cells against hypoxic neural injury in SH-SY5Y cells [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2021
Objective(s): Dental pulp stem cells (DPSCs) can differentiate into functional neurons and have the potential for cell therapy in neurological diseases.
Farahnaz Ahmadi   +4 more
doaj   +1 more source

Production of high-titer helper-free retroviruses by transient transfection. [PDF]

open access: greenProceedings of the National Academy of Sciences of the United States of America, 1993
The generation of high-titer, helper-free retroviruses by transient transfection has been achieved by using the highly transfectable 293T cell line into which are stably introduced constructs that express retroviral packaging functions.
Warren S. Pear   +3 more
openalex   +2 more sources

Induction of Bleb Structures in Lipid Nanoparticle Formulations of mRNA Leads to Improved Transfection Potency

open access: yesAdvances in Materials, 2023
The transfection potency of lipid nanoparticle (LNP) mRNA systems is critically dependent on the ionizable cationic lipid component. LNP mRNA systems composed of optimized ionizable lipids often display distinctive mRNA‐rich “bleb” structures.
Miffy H Y Cheng   +12 more
semanticscholar   +1 more source

Transfection types, methods and strategies: a technical review

open access: yesPeerJ, 2021
Transfection is a modern and powerful method used to insert foreign nucleic acids into eukaryotic cells. The ability to modify host cells’ genetic content enables the broad application of this process in studying normal cellular processes, disease ...
Z. Chong, S. Yeap, W. Ho
semanticscholar   +1 more source

Inhibition of Small-Conductance, Ca2+-Activated K+ Current by Ondansetron

open access: yesFrontiers in Pharmacology, 2021
Background: Small-conductance Ca2+-activated K+ channels (SK channels) have been proposed as antiarrhythmic targets for the treatment of atrial fibrillation.
Shuai Guo   +4 more
doaj   +1 more source

An Overview of Methods and Tools for Transfection of Eukaryotic Cells in vitro

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Transfection is a powerful analytical tool enabling studies of gene products and functions in eukaryotic cells. Successful delivery of genetic material into cells depends on DNA quantity and quality, incubation time and ratio of transfection reagent to ...
A. Fus-Kujawa   +6 more
semanticscholar   +1 more source

Transfection by Electroporation [PDF]

open access: yesCurrent Protocols in Cell Biology, 1992
AbstractElectroporation–the use of high‐voltage electric shocks to introduce DNA into cells–can be used with most cell types, yields a high frequency of both stable transformation and transient gene expression, and, because it requires fewer steps, can be easier than alternate techniques.
Richard Heller, Huntington Potter
openaire   +13 more sources

Headgroup modification of cholesterol-based cationic lipids: Synthesis, transfection efficiency evaluation, and serum compatibility [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2020
There were two objectives for this study. First, it focused on eight lipids having cholesterol as hydrophobic tails, carbamate linkers, and different polar headgroups.
Chopaka Thongbamrer   +9 more
doaj   +1 more source

Transfection of Platyhelminthes [PDF]

open access: yesBioMed Research International, 2015
Flatworms are one of the most diverse groups within Lophotrochozoa with more than 20,000 known species, distributed worldwide in different ecosystems, from the free-living organisms in the seas and lakes to highly specialized parasites living in a variety of hosts, including humans.
Juan Pedro Laclette   +3 more
openaire   +2 more sources

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