Results 21 to 30 of about 568,858 (297)
Protamine-Based Strategies for RNA Transfection
Pharmaceutics, 2021 Protamine is a natural cationic peptide mixture mostly known as a drug for the neutralization of heparin and as a compound in formulations of slow-release insulin.
Natalia Teresa Jarzebska +4 more
doaj +1 more source
The expression of the ACTH receptor
Brazilian Journal of Medical and Biological Research, 2000 Adrenal glucocorticoid secretion is regulated by adrenocorticotropic hormone (ACTH) acting through a specific cell membrane receptor (ACTH-R). The ACTH-R is a member of the G protein superfamily-coupled receptors and belongs to the subfamily of ...
L.L.K. Elias, A.J.L. Clark
doaj +1 more source
Functional differences between protamine preparations for the transfection of mRNA
Drug Delivery, 2020 Protamine is a natural cationic peptide mixture used as a drug for the neutralization of heparin and in formulations of slow-release insulin. In addition, Protamine can be used for the stabilization and delivery of nucleic acids (antisense, small ...
Natalia Teresa Jarzebska +7 more
doaj +1 more source
Infectious viruses from transfected SARS-CoV-2 genomic RNA
Frontiers in Bioengineering and Biotechnology, 2023 SARS-CoV-2 emerged at the end of 2019, and like other novel pathogens causing severe symptoms, WHO recommended heightened biosafety measures for laboratories working with the virus.
Elina Väisänen +7 more
doaj +1 more source
Plate-based transfection and culturing technique for genetic manipulation of
Malaria Journal, 2012 Genetic manipulation of malaria parasites remains an inefficient, time-consuming and resource-intensive process. Presented here is a set of methods for 96-well plate-based transfection and culture that improve the efficiency of genetic manipulation of ...
Caro Florence +2 more
doaj +1 more source
Frontiers in Genome Editing, 2021 Field cress (Lepidium campestre) is a potential oilseed crop that has been under domestication in recent decades. CRISPR/Cas9 is a powerful tool for rapid trait improvement and gene characterization and for generating transgene-free mutants using ...
Sjur Sandgrind +4 more
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2017 RNA interference (RNAi)-based strategies that mediate the specific knockdown of target genes by administration of small interfering RNAs (siRNAs) could be applied for treatment of presently incurable neurodegenerative diseases such as Parkinson’s disease.
Christin Helmschrodt +9 more
doaj +1 more source
Effect of lysogeny on transfection and transfection enhancement in Bacillus subtilis [PDF]
Journal of Bacteriology, 1975 Strains of Bacillus subtilis 168 lysogenic for bacteriophage phi105 transfer with deoxyribonucleic acid (DNA) isolated from bacteriophage SPO2 at a higher efficiency than non-lysogenic strains. This enhancement of transfection was not the result of recombination between bacteriophages SPO2 and phi105. Superinfection marker rescue increased transfection
Frank E. Young, G A Wilson, R E Yasbin
openaire +3 more sources
Journal of the Formosan Medical Association, 2011 Gene delivery into liver cancer cells has been a problem. This study aimed to understand the effect of using PEGI/Fe3O4 nanomagnetic fluid as a gene vector for liver cancer gene therapy.
Baoxiong Zhuang +6 more
doaj +1 more source
Current Issues in Molecular Biology, 2023 Transfection is a contemporary approach for introducing foreign genetic material into target cells. The effective transport of genetic materials into cells is mostly influenced by (a) the characteristics of the genetic material (quantity and quality), (b)
Hanaa Alkharobi
doaj +1 more source