Clinical and Translational DiscoveryThis study was focused to formulate and optimize transferosomes encapsulating ketoconazole (KTZ) for its repurposed use as a hair growth promoting agent.
Madhvi Mishra +11 more
doaj +2 more sources
Preparation and evaluation of hair growth promoting effect of transferosomes containing red clover extract and caffeine alone or in combination [PDF]
Avicenna Journal of PhytomedicineObjective: Trifolium pratense L. (Red clover) belongs to the Leguminosae family. This study was designed to develop transferosome formulations containing red clover extract or caffeine alone or in combination and evaluate their effects on hair growth in ...
Valiollah Hajhashemi +4 more
doaj +2 more sources
Investigating the Targeting Power to Brain Tissues of Intranasal Rasagiline Mesylate-Loaded Transferosomal In Situ Gel for Efficient Treatment of Parkinson’s Disease [PDF]
Pharmaceutics, 2023 Rasagiline mesylate (RSM) is a hydrophilic drug with poor oral bioavailability (36%) because of hepatic first-pass metabolism. The present study focuses on delivering RSM directly to the brain through its inclusion within transferosomal in situ gel ...
Hala N. ElShagea +4 more
doaj +2 more sources
Enhanced Topical Delivery of Methotrexate via Transferosome-Loaded Microneedle Array Patch: Formulation, Optimization, and In Vitro–In Vivo Assessment [PDF]
PharmaceuticalsBackground: Conventional approaches in treating psoriasis demonstrate several complications. methotrexate (MTX) has been frequently used for its efficacy in managing moderate to severe psoriasis.
Snehal Shinde +4 more
doaj +2 more sources
Fabrication and application of targeted ciprofloxacin nanocarriers for the treatment of chronic bacterial prostatitis [PDF]
International Journal of Pharmaceutics: XPathogenic bacteria cause chronic bacterial prostatitis (CBP). CPB is characterized by urinary tract infection and persistence of pathogenic bacteria in prostatic secretion.
Sahar I. Mohammad +7 more
doaj +2 more sources
Nanotechnology in Skin Cancer Therapy: Recent Progress in Targeted Delivery. [PDF]
Kaohsiung J Med SciABSTRACT Skin cancer, encompassing melanoma and non‐melanoma types, remains a significant public health concern globally. Conventional therapies—such as surgery, radiotherapy, chemotherapy, and immunotherapy—are constrained by poor skin penetration, systemic toxicity, and high recurrence rates.
Yu HP, Hsu CY, Fang JY, Lin ZC.
europepmc +2 more sources
Review on Transferosomes and Transferosomal Gels
Journal of Pharmaceutical Research International, 2021 Transdermal drug delivery systems (TDDS), which are self-administrable and non-invasive, can improve bioavailability and patient compliance by bypassing first-pass metabolism. Vesicular-based TDDS have attracted a lot of attention in recent years because they're designed for controlled, efficient, and targeted drug delivery.
R. Santosh Kumar, P. Kranthi Kumar
openaire +2 more sources
Frontiers in Pharmacology, 2022 Transdermal drug delivery aims to create a safe and effective method of administering drugs through the skin that attracts a lot of attention and investment due to the constant progress in the field.
Rong-Ping Chen +3 more
doaj +1 more source
Transferosomes: A Novel Topical Approach
Journal of Drug Delivery and Therapeutics, 2023 Transdermal drug delivery technologies have gained attention in recent years due to their advantages over conventional drug delivery systems. Transdermal drug delivery is limited because the stratum corneum functions as a barrier. Transferosomes are ultradeformable vesicles consisting of a lipid bilayer with phospholipids and an edge activator.
M. Sunitha Reddy, Shruti Rao Kodi
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Nanotechnology-Based Drug Delivery Systems in the Transdermal Treatment of Melanoma [PDF]
Advanced Pharmaceutical Bulletin, 2023 The incidence rate of melanoma is dramatically increasing worldwide, raising it to the fifth most common cancer in men and the sixth in women currently. Resistance generally occurs to the agents used in chemotherapy; besides their high toxicity destroys ...
Zahra Saeidi +3 more
doaj +1 more source