Results 21 to 30 of about 760 (163)

Formulation and evaluation of Lamivudine transferosomal gel

Journal of Drug Delivery and Therapeutics, 2022
Aim and objective: The aim of the study was to formulate and evaluate Transferosomal gel of lamivudine. Method:Lamivudine transferosomes was prepared using thin film hydration method taking span 80, Polyoxyethylene lauryl ether in different  proportion. the formulation was characterised by UV spectroscopy, FTIR, in-vitro drug release, gel evaluations.
S.M. Shahidulla, Syeda Hassan Yameen
openaire   +1 more source

Cyanocobalamin Ultraflexible Lipid Vesicles: Characterization and In Vitro Evaluation of Drug-Skin Depth Profiles

Pharmaceutics, 2021
Atopic dermatitis (AD) and psoriasis are the most common chronic inflammatory skin disorders, which importantly affect the quality of life of patients who suffer them.
Antonio José Guillot, Enrique Jornet-Mollá, Natalia Landsberg, Carmen Milián-Guimerá, M. Carmen Montesinos, Teresa M. Garrigues, Ana Melero   +6 more
doaj   +1 more source

Dermal and Transdermal Drug Delivery through Vesicles and Particles: Preparation and Applications [PDF]

Advanced Pharmaceutical Bulletin, 2022
Transdermal delivery over the past decade has become the field of interest for drug delivery due to its various advantages such as no first-pass metabolism, increased drug bioavailability, and easy administration. Different vesicle systems like ethosomes,
Unnati Garg, Karuna Jain
doaj   +1 more source

DOE-Assisted Formulation, Optimization, and Characterization of Tioconazole-Loaded Transferosomal Hydrogel for the Effective Treatment of Atopic Dermatitis: In Vitro and In Vivo Evaluation

Gels, 2023
The present study was performed to determine the therapeutic effects of tioconazole (Tz)-loaded novel transferosome carriers (TFs) for the treatment of atopic dermatitis (AD).
Rohini Kharwade, Nemat Ali, Purushottam Gangane, Kapil Pawar, Sachin More, Muzaffar Iqbal, Abid R. Bhat, Abdullah F. AlAsmari, Mohammed Kaleem   +8 more
doaj   +1 more source

ELASTIC VESICLES FOR ENHANCING THE TOPICAL REPURPOSED EFFECT OF PROPRANOLOL AGAINST CANDIDA ALBICANS [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University
The goal of this investigation was to load transferosomes with the repurposed antifungal drug propranolol to treat candida albicans topically. The production of transferosomes for enhancing propranolol topical administration was the focus of this study ...
Mohammed N. Fenjan, Zaman Kareem Hanan, Nawras.j. Ka   +2 more
doaj   +1 more source

Intranasal Nanotransferosomal Gel for Quercetin Brain Targeting: II. Antidepressant Effect in an Experimental Animal Model

Pharmaceutics, 2023
Depression is a serious mental disorder and the most prevalent cause of disability and suicide worldwide. Quercetin (QER) demonstrated antidepressant effects in rats exhibiting anxiety and depressive-like behaviors.
Mohammed H. Elkomy, Fatma I. Abo El-Ela, Randa Mohammed Zaki, Omar A. Alsaidan, Mohammed Elmowafy, Ameeduzzafar Zafar, Khaled Shalaby, Mohamed A. Abdelgawad, Hany A. Omar, Rania Salama, Hussein M. Eid   +10 more
doaj   +1 more source

Intranasal Nanotransferosomal Gel for Quercetin Brain Targeting: I. Optimization, Characterization, Brain Localization, and Cytotoxic Studies

Pharmaceutics, 2023
Numerous neurological disorders have a pathophysiology that involves an increase in free radical production in the brain. Quercetin (QER) is a nutraceutical compound that shields the brain against oxidative stress-induced neurodegeneration.
Mohammed H. Elkomy, Randa Mohammed Zaki, Omar A. Alsaidan, Mohammed Elmowafy, Ameeduzzafar Zafar, Khaled Shalaby, Mohamed A. Abdelgawad, Fatma I. Abo El-Ela, Mostafa E. Rateb, Ibrahim A. Naguib, Hussein M. Eid   +10 more
doaj   +1 more source

Formulation, optimization, and nephrotoxicity evaluation of an antifungal in situ nasal gel loaded with voriconazole‒clove oil transferosomal nanoparticles

Drug Delivery, 2021
Fungal infections of the paranasal cavity are among the most widely spread illnesses nowadays. The aim of the current study was to estimate the effectiveness of an in situ gel loaded with voriconazole‒clove oil nano-transferosomes (VRC-CO-NT) in ...
Ahmed K. Kammoun, Alaa Khedr, Maha A. Hegazy, Ahmad J. Almalki, Khaled M. Hosny, Walaa A. Abualsunun, Samar S. A. Murshid, Rana B. Bakhaidar   +7 more
doaj   +1 more source

Formulation and Evaluation of a Transferosomal Gel of Famciclovir for Transdermal Use. [PDF]

Turk J Pharm Sci, 2023
Famciclovir, the drug of choice for cold sores and recurrent genital herpes, has poor oral bioavailability and is associated with numerous side effects. The study aimed to explore the possibility of transdermal application of famciclovir through a transferosome-loaded gelling system to localize the drug at the site of application with improved ...
Bhattacharyya S, Lakshmanan KT, Muthukumar A.   +2 more
europepmc   +3 more sources

Neomycin sulphate loaded transferosomal vesicles

International journal of health sciences, 2022
The objective of research study was to fabricate neomycin sulphate loaded transferosomal vesicles by modified handshaking technique to increase the permeability of drug through vaginal mucosa. Tween80, span80, tween20, span20, Cremophor EL, brij35, sodium deoxycholate were used at three different concentrations by keeping drug concentration remains ...
Sasikala Allam, G. S. Annammadevi
openaire   +1 more source