Results 61 to 70 of about 9,216,194 (230)
The role of TGF-β and epithelial-to mesenchymal transition in diabetic nephropathy [PDF]
, 2011 Transforming Growth Factor-beta (TGF-β) is a pro-sclerotic cytokine widely associated with the development of fibrosis in diabetic nephropathy. Central to the underlying pathology of tubulointerstitial fibrosis is epithelial-to-mesenchymal transition ...
Hills, Claire E. +3 more
core +1 more source
Hydrogel platforms for 3D cardiac tissue engineering and fibrotic disease modelling
FEBS Open Bio, EarlyView.Hydrogel‐based cardiac tissue models are advancing our understanding of heart health and disease. By incorporating electrical conductivity, aligned structures, and tunable mechanical properties, these platforms better replicate the complex environment of native heart tissue.
Harrison Porritt +2 more
wiley +1 more source
, 1997 Transforming growth factor β-1 (TGF-β1) is a potent inhibitor of hepatocyte growth both in vivo and in vitro. In this study, we analyzed the effects of TGF-β1 on both naturally occurring and diethylnitrosamine- induced hepatocarcinogenesis using single ...
Factor, Valentina M. +5 more
core +1 more source
ANALYSIS OF THE LEVEL OF TRANSFORMING GROWTH FACTOR β1 IN CHILDREN WITH BRONCHIAL ASTHMA
Мать и дитя в Кузбассе, 2019 Achieving control over the symptoms of the disease is the most important and serious task in the treatment of bronchial asthma. The cause of uncontrolled flow may be the activation of tissue growth factors that trigger the process of remodeling the ...
Наталья Леонидовна Потапова +1 more
doaj
HeliyonIntroduction: Marfan syndrome is a rare disease in which different metabolic pathways and immune mediators such as transforming growth factor β1, interleukins and metalloproteinases participate.
María Elena Soto +8 more
doaj +1 more source
Transforming growth factor beta-1 (TGF-β1) expression in patients with adenomyosis [PDF]
Revista Brasileira de Ginecologia e ObstetríciaObjective: To compare Transforming growth factor beta-1 (TGF-β1) expression in patients with and without adenomyosis. Methods: A prospective design was performed including 49 patients submitted to hysterectomy.
Andreia Jacobo +4 more
doaj +1 more source
, 1999 Transforming growth factor β1(TGF‐β1)–inducible transcription factors have recently elicited interest because of their critical role in the regulation of cell proliferation, differentiation, and apoptosis.
Bronk, Steven F +4 more
core +1 more source
Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons +33 more
wiley +1 more source
TGF-β1 Negatively Regulates the Number and Function of Hematopoietic Stem Cells
Stem Cell Reports, 2018 Summary: Transforming growth factor β1 (TGF-β1) plays a role in the maintenance of quiescent hematopoietic stem cells (HSCs) in vivo. We asked whether TGF-β1 controls the cell cycle status of HSCs in vitro to enhance the reconstitution activity.
Xiaofang Wang +14 more
doaj +1 more source
, 2018 Transforming growth factor (TGF)-β1 mediates glycosaminoglycan (GAG) chain hyperelongation on secreted proteoglycans and these modifications are associated with increased lipid binding in the vessel wall and the development of atherosclerosis.
Kamato, Danielle +7 more
core +1 more source