Results 11 to 20 of about 4,740,665 (262)

Production and Purification of Virus-Like Particles by Transient Expression in Plants [PDF]

, 2023
Transient expression in plants has become a useful production system for virus-like particle (VLP) expression. High yields and flexible approaches to assembling complex VLPs, combine with ease of scale-up and inexpensive reagents to provide an attractive
Esquirol, L, McNeale, D, Sainsbury, F, Venturi, M   +3 more
core   +1 more source

Automation of large scale transient protein expression in mammalian cells [PDF]

, 2011
Traditional mammalian expression systems rely on the time-consuming generation of stable cell lines; this is difficult to accommodate within a modern structural biology pipeline.
Susan Daenke, E. Yvonne Jones, Siebold, Christian, Daenke, Susan, Christian Siebold, Bishop, Benjamin, Margaret Jones, Clay, Jordan E, A. Radu Aricescu, Benjamin Bishop, Aricescu, Alexandru R, Weixian Lu, Stuart, David I, Yuguang Zhao, Jones, Margaret, Lu, Weixian, David I. Stuart, Jordan E. Clay, Zhao, Yuguang, Jones, E Yvonne   +19 more
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Updates in inducible transgene expression using viral vectors : from transient to stable expression [PDF]

, 2015
The prospect of economically producing useful biologics in plants has greatly increased with the advent of viral vectors. The ability of viral vectors to amplify transgene expression has seen them develop into robust transient platforms for the high ...
Mortimer, Cara L., Dale, James L., Dugdale, Benjamin   +2 more
core   +1 more source

Transient receptor potential channel polymorphisms are associated with the somatosensory function in neuropathic pain patients. [PDF]

, 2011
Transient receptor potential channels are important mediators of thermal and mechanical stimuli and play an important role in neuropathic pain. The contribution of hereditary variants in the genes of transient receptor potential channels to neuropathic ...
Maihöfner Christian, Magerl Walter, Zhu, Jihong, Cascorbi Ingolf, Roman Rolke, Maihöfner, Christian, Binder Andreas, Treede, Rolf-Detlef, Faltraco, Frank, Flor, Herta, Rolf-Detlef Treede, Richter Helmut, Thomas R. Tölle, Nurcan Uçeyler, Huge, Volker, Mike Ufer, Christian Maihöfner, May, Denisa, Andrea Scherens, Uçeyler, Nurcan, Ralf Baron, May Denisa, Huge Volker, Cascorbi, Ingolf, Scherens, Andrea, Ufer, Mike, Gunnar Wasner, Binder, Andreas, Jihong Zhu, Herta Flor, Volker Huge, Helmut Richter, Tölle, Thomas R., Maier Christoph, Maier, Christoph, Thomas R Tölle, Tölle Thomas R., Zhu Jihong, Achim Berthele, Gierthmühlen Janne, Baron Ralf, Faltraco Frank, Magerl, Walter, Andreas Binder, Gierthmühlen, Janne, Christoph Maier, Richter, Helmut, Flor Herta, Wasner Gunnar, Denisa May, Scherens Andrea, Baron, Ralf, Üçeyler Nurcan, Haenisch Sierk, Rolke, Roman, Berthele Achim, Frank Faltraco, Ingolf Cascorbi, Berthele, Achim, Treede Rolf-Detlef, Ufer Mike, Haenisch, Sierk, Wasner, Gunnar, Janne Gierthmühlen, Sierk Haenisch, Rolke Roman, Walter Magerl, Binder, A;May, D;Baron, R;Maier, C;Tölle, TR;Treede, RD;Berthele, A;Faltraco, F;Flor, H;Gierthmühlen, J;Haenisch, S;Huge, V;Magerl, W;Maihöfner, C;Richter, H;Rolke, R;Scherens, A;Üçeyler, N;Ufer, M;Wasner, G;Zhu, J;Cascorbi, I   +67 more
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Functional modulation of the transient outward current Ito by KCNE beta-subunits and regional distribution in human non-failing and failing hearts [PDF]

, 2006
Objectives: The function of Kv4.3 (KCND3) channels, which underlie the transient outward current I,, in human heart, can be modulated by several accessory subunits such as KChIP2 and KCNE1-KCNE5.
Cotella, D., Varró, András, Ravens, U., Wettwer, E., Radicke, S., Banse, U., Jost, Norbert, Graf, E., Tseng, G.   +8 more
core   +1 more source

Remodelling of human atrial K+ currents but not ion channel expression by chronic β-blockade [PDF]

, 2011
Chronic β-adrenoceptor antagonist (β-blocker) treatment in patients is associated with a potentially anti-arrhythmic prolongation of the atrial action potential duration (APD), which may involve remodelling of repolarising K+ currents.
Currie, S., Tellez, James O, Julie A. Russell, Kane, Kathleen A, Jhund, Pardeep S, Boyett, M.R., Rankin, A.C., Pardeep S. Jhund, Mark R. Boyett, Dempster, John, Marshall, Gillian E., John Dempster, Currie, Susan, Russell, J.A., Workman, Antony J., Marshall, Gillian E, Workman, A.J., Marshall, G.E., Russell, Julie A, Dempster, J., Rankin, Andrew C, Russell, Julie A., Gillian E. Marshall, Tellez, James O., Boyett, Mark R, Kathleen A. Kane, Boyett, Mark R., Andrew C. Rankin, Rankin, Andrew C., Kane, K.A., Workman, Antony J, Tellez, J.O., Antony J. Workman, Kane, Kathleen A., Jhund, P.S., Susan Currie, James O. Tellez, Jhund, Pardeep S.   +37 more
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Innovation in plant-based transient protein expression for infectious disease prevention and preparedness

, 2020
Addressing new challenges in global health and biosecurity requires responsive and accessible platforms for the manufacture of preventative or therapeutic interventions.
Sainsbury, Frank
core   +1 more source

Functional expression of TRPV4 channels in human collecting duct cells : implications for secondary hypertension in diabetic nephropathy [PDF]

, 2012
Background. The Vanilloid subfamily of transient receptor potential (TRPV) ion channels has been widely implicated in detecting osmotic and mechanical stress.
Hills, Claire E., Bland, Rosemary, Squires, Paul E.   +2 more
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Serum proteome profiling identifies novel and powerful markers of cystic fibrosis liver disease. [PDF]

, 2013
Cystic Fibrosis associated liver disease (CFLD) develops in approximately 30% of CF patients. However, routine sensitive diagnostic tools for CFLD are lacking. Within this study, we aimed to identify new experimental biomarkers for the detection of CFLD.
Richard Schulz, Martin Roderfeld, Roderfeld, Martin, Lisa Hage, Timo Rath (389419), Reinhart Zachoval (76840), Katrin Menendez Menendez (389422), Lutz Naehrlich (389423), Martin Roderfeld (389425), Hage, Lisa, Marion Kügler, Richard Schulz (389424), Marion Kügler (389421), Elke Roeb (389426), Timo Rath, Kügler, Marion, Rath, Timo, Roeb, Elke, Katrin Menendez Menendez, Reinhart Zachoval, Elke Roeb, Menendez Menendez, Katrin, Lutz Naehrlich, Lisa Hage (389420), Zachoval, Reinhart, Naehrlich, Lutz, Schulz, Richard, Roeb Elke, Rath Timo, Hage Lisa, Schulz Richard, Kügler Marion, Zachoval Reinhart, Roderfeld Martin, Menendez Menendez Katrin, Naehrlich Lutz   +35 more
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Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source