Results 101 to 110 of about 111,852,927 (168)
The Journal of Physiology, EarlyView.Abstract figure legend Calmodulin (CaM) is a ubiquitous calcium (Ca2+) sensor that translates intracellular Ca2+ signals into modulation of hundreds of effector proteins including ion channels. CaM is increasingly recognized as a key regulator of the transient receptor potential (TRP) channel family, yet the underlying ‘calmodulation playbook’ is only ...
Aden M. Alemayhu, Candice E. Paulsen
wiley +1 more source
The physiological function and pathological significance of transient receptor potential ankyrin 1 channels in the cerebral artery endothelium [PDF]
, 2015 2015 Spring.Includes bibliographical references.Endothelial cell Ca2+ dynamics have a significant influence on cerebrovascular tone. Several transient receptor potential (TRP) channels have been shown to mediate Ca2+ influx in the endothelium, including ...
Dinenno, Frank, committee member +5 more
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ANK1 and EPB41 Variants and The Risk of Glucocorticoid‐Induced Osteonecrosis
Arthritis &Rheumatology, Volume 78, Issue 11, Page 2378-2389, November 2026.Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen +21 more
wiley +1 more source
Proteomic signatures of equine dental tooth tissues in ageing and disease
Equine Veterinary Journal, Volume 58, Issue 6, Page 1552-1569, November 2026.Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen +8 more
wiley +1 more source
Development of the G3 Designed ankyrin repeat protein (DARPin) for HER2 imaging [PDF]
, 2015 Background: Human epidermal growth factor receptor-2 (HER2) expression predicts response to anti-HER2 therapy in breast and gastric cancer. HER2 status is assessed by tumour biopsy but this may not be representative of the larger tumour mass or other ...
Goldstein, RM
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Toward Ideal Proximity‐Driven Reactions in Chemical Biology
ChemBioChem, Volume 27, Issue 19, 14 October 2026.Building on established principles of molecular templation, this perspective explores how molecular recognition can control chemical reactivity in space and time and outlines the design principles of an ideal proximity‐driven reaction for chemical biology.
Dominik Schauenburg
wiley +1 more source
, 2020 Transient receptor potential ankyrin 1 (TRPA1) is a membrane-bound ion channel found in neurons, where it mediates nociception and neurogenic inflammation.
Vuolteenaho, Katriina +17 more
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유지놀에 의한 Transient Receptor Potential Ankyrin 1의 활성화 [PDF]
, 2015 학위논문 (석사)-- 서울대학교 대학원 : 치의과학과, 2015. 2. 오석배.The structural similarity of eugenol to cinnamaldehyde, an active ligand for transient receptor potential ankyrin 1 (TRPA1), suggests that eugenol might produce its effect via TRPA1 in addition to TRPV1 as we ...
임상택
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Arthritis Research & TherapyIntroduction Transient receptor potential ankyrin 1 (TRPA1) is a calcium-permeable cation channel expressed in multiple cell types, including nociceptive C-fibers innervating the knee joint, and is activated by mechanical, inflammatory, and oxidative ...
Karsyn N. Bailey +3 more
doaj +1 more source
, 2011 Background Cross talk between peripheral nociceptors belonging to the transient receptor potential vanilloid receptor subtype-1 (TRPV1) and ankyrin subtype-1 (TRPA1) family has been demonstrated recently.
Derek S. Damron +4 more
core +1 more source