Results 1 to 10 of about 10,843 (104)

Transient Receptor Potential Ankyrin 1 (TRPA1) Channel as a Sensor of Oxidative Stress in Cancer Cells [PDF]

Cells, 2023
Moderate levels of reactive oxygen species (ROS), such as hydrogen peroxide (H2O2), fuel tumor metastasis and invasion in a variety of cancer types. Conversely, excessive ROS levels can impair tumor growth and metastasis by triggering cancer cell death ...
Francesco Moccia, Daniela Montagna
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Transient Receptor Potential Ankyrin 1 Mediates Hypoxic Responses in Mice [PDF]

Frontiers in Physiology, 2020
Transient receptor potential ankyrin 1 (TRPA1) is a non-selective cation channel that is broadly expressed in sensory pathways, such as the trigeminal and vagus nerves.
Sichong Chen, Sichong Chen, Nobuaki Takahashi, Nobuaki Takahashi, Changping Chen, Changping Chen, Jordan L. Pauli, Chiharu Kuroki, Chiharu Kuroki, Jun Kaminosono, Hideki Kashiwadani, Yuichi Kanmura, Yasuo Mori, Shaowu Ou, Liying Hao, Tomoyuki Kuwaki   +15 more
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Function and therapeutic potential of transient receptor potential ankyrin 1 in fibrosis [PDF]

Frontiers in Pharmacology, 2022
The transient receptor potential (TRP) protein superfamily is a special group of cation channels expressed in different cell types and signaling pathways.
Yicheng Wei, Yicheng Wei, Yicheng Wei, Jialuo Cai, Jialuo Cai, Ruiqiu Zhu, Ruiqiu Zhu, Ke Xu, Ke Xu, Hongchang Li, Jianxin Li   +10 more
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Transient receptor potential ankyrin 1 in the knee is involved in osteoarthritis pain [PDF]

Biochemistry and Biophysics Reports, 2023
Transient receptor potential families play important roles in the pathology of osteoarthritis (OA) of the knee. While transient receptor potential ankyrin 1 (TRPA1) is also an essential component of the pathogenesis of various arthritic conditions, its ...
Hidenobu Tamai, Manabu Yamanaka, Wataru Taniguchi, Naoko Nishio, Daisuke Fukui, Terumasa Nakatsuka, Hiroshi Yamada   +6 more
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The role of transient receptor potential ankyrin 1 in pyroptosis during pulpitis development [PDF]

BMC Oral Health
Background Vital pulp therapy has been a widely adopted for managing pulp diseases, in which the control of pulpitis progression is critical. Although the transient receptor potential ankyrin 1 (TRPA1) channel mediates pain transduction and inflammatory ...
Sixue Huang, Huihui Chang, Qinqi Zhang, Xinmin Liao, Ge Yang, Guicong Ding, Chanchan Chen   +6 more
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Local upregulation of transient receptor potential ankyrin 1 and transient receptor potential vanilloid 1 ion channels in rectosigmoid deep infiltrating endometriosis

Molecular Pain, 2017
Transient Receptor Potential Vanilloid 1 (TRPV1) and Transient Receptor Potential Ankyrin 1 (TRPA1) expressed mainly by primary sensory neurons function as major nociceptive integrators.
Noémi Bohonyi, Krisztina Pohóczky, Bálint Szalontai, Anikó Perkecz, Krisztina Kovács, Béla Kajtár, Lajos Orbán, Tamás Varga, Sarolta Szegedi, József Bódis, Zsuzsanna Helyes, Miklós Koppán   +11 more
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Toll-like receptor 4 signaling pathway in sensory neurons mediates remifentanil-induced postoperative hyperalgesia via transient receptor potential ankyrin 1 [PDF]

Molecular Pain, 2023
Background: Remifentanil-induced postoperative hyperalgesia (RIH) refers to a state of hyperalgesia or aggravated pre-existing pain after remifentanil exposure. There has been considerable interest in understanding and preventing RIH.
Xiaowen Liu, Ruisong Gong, Liang Peng, Jing Zhao   +3 more
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Regulation of transient receptor potential ankyrin 1 by traditional Chinese medicine drugs and their active ingredients [PDF]

Frontiers in Pharmacology
Transient receptor potential ankyrin 1 (TRPA1) has attracted substantial attention for its role as a thermal receptor and regulator of temperature and pain sensing.
Yunlong Fang, Yunlong Fang, Chunxin Lei, Chunxin Lei, Zihan Wang, Zihan Wang, Longxiao Liu, Longxiao Liu, Yanyu Chen, Yanyu Chen, Feng Chen, Feng Chen, Jingxuan Li, Jingxuan Li, Zhikun Tu, Zhikun Tu, Qingwen Tao, Yuan Xu   +17 more
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Lack of transient receptor potential ankyrin 1 (TRPA1) retards cutaneous wound healing in mice: A preliminary study [PDF]

Biochemistry and Biophysics Reports, 2022
Wound healing is an important process in various diseases, and elucidating the underlying mechanism is essential for developing therapeutic strategies.
Shizumasa Murata, Manabu Yamanaka, Wataru Taniguchi, Daiki Kajioka, Kentaro Suzuki, Gen Yamada, Yuka Okada, Shizuya Saika, Hiroshi Yamada   +8 more
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Transient Receptor Potential Ankyrin 1 Channels in Inflammation and Cancer: Accelerators or Brakes? [PDF]

Function, 2022
Shuang Peng
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