Results 151 to 160 of about 28,002 (191)

Transient receptor potential ankyrin 1 channel modulates the abuse-related mechanisms of methamphetamine through interaction with dopamine transporter. [PDF]

Br J Pharmacol
Hur KH, Lee Y, Donio AL, Kim SK, Lee BR, Seo JY, Kundu D, Kim KM, Kohut SJ, Lee SY, Jang CG.   +10 more
europepmc   +1 more source

Correction to: Evolutionary Tuning of Transient Receptor Potential Ankyrin 1 Underlies the Variation in Heat Avoidance Behaviors among Frog Species Inhabiting Diverse Thermal Niches. [PDF]

Mol Biol Evol, 2022
europepmc   +1 more source

Transient Receptor Potential Ankyrin 1 (TRPA1) Modulation by 4-Hydroxynonenal (4-HNE) in Pancreatic Adenocarcinoma Cell Lines: Putative Roles for Therapies. [PDF]

Pharmaceuticals (Basel)
Piciu F, Domocos D, Chiritoiu G, Chiritoiu-Butnaru M, Mernea M, Popescu CG, Mihai DP, Galateanu B, Hudita A, Babes A, Cucu D.   +10 more
europepmc   +1 more source

Inhibition of Dorsal Root Ganglia Transient Receptor Potential Ankyrin 1 Upregulation Contributes to the Protective Effect of Morphine Against Gastric Mucosal Damage Induced by Water-Immersion Restraint Stress. [PDF]

Turk J Gastroenterol
Jiang Q, Jiang P, Guo M, Xie C, Ling Q, Zhao G, Tu W, Li X.   +7 more
europepmc   +1 more source

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Activation of transient receptor potential ankyrin 1 by hydrogen peroxide

European Journal of Neuroscience, 2008
AbstractHydrogen peroxide (H2O2), which is contained in industrial products, is also generated within cells. H2O2 causes pain but it has not been elucidated how it activates sensory neurons in the pain pathway. Here we show that transient receptor potential ankyrin 1 (TRPA1), expressed by sensory neurons in the pain pathway, is a receptor for H2O2 ...
Yosuke, Sawada, Hiroshi, Hosokawa, Kiyoshi, Matsumura, Shigeo, Kobayashi   +3 more
exaly   +3 more sources

Modulation of Transient Receptor Vanilloid 1 Activity by Transient Receptor Potential Ankyrin 1

Molecular Pharmacology, 2014
Transient receptor potential vanilloid 1 (TRPV1) is a nonselective ligand-gated cation channel responding to noxious heat, protons, and chemicals such as capsaicin. TRPV1 is expressed in sensory neurons and plays a critical role in pain associated with tissue injury, inflammation, and nerve lesions.
Christoph Stein, Viola Seitz, Christian Zollner   +2 more
exaly   +3 more sources

Upregulation of transient receptor potential ankyrin 1 (TRPA1) but not transient receptor potential vanilloid 1 (TRPV1) during primary tooth carious progression

Journal of Oral Biosciences, 2023
To quantify the changes in Transient Receptor Potential Ankyrin 1 (TRPA1) and Transient Receptor Potential Vanilloid 1 (TRPV1) expression throughout the process of inflammation induced by caries.Forty primary teeth were obtained from children requiring dental extractions under local or general anesthesia.
Alisa Wichaidit, Namthip Patinotham, Kullanun Nukaeow, Aunwaya Kaewpitak   +3 more
openaire   +3 more sources

Transient receptor potential ankyrin-1 participates in visceral hyperalgesia following experimental colitis

Neuroscience Letters, 2008
Transient receptor potential ankyrin-1 (TRPA1) is an important receptor that contributes to inflammatory pain. However, previous studies were mainly concerned with its function in somatic hyperalgesia while few referred to visceral, especially colonic inflammatory hyperalgesia.
Yanqing Li, Xiuli Zuo, Yan Bo Yu
exaly   +3 more sources

Human Transient Receptor Potential Ankyrin 1 Channel: Structure, Function, and Physiology

Sub-cellular biochemistry
The transient receptor potential ion channel TRPA1 is a Ca2+-permeable nonselective cation channel widely expressed in sensory neurons, but also in many nonneuronal tissues typically possessing barrier functions, such as the skin, joint synoviocytes, cornea, and the respiratory and intestinal tracts.
Viktorie, Vlachova, Ivan, Barvik, Lucie, Zimova   +2 more
openaire   +3 more sources

Protective Effect of Transient Receptor Potential Ankyrin 1 Inhibition on Renal Ischemia Reperfusion Injury in Rats

Journal of Biochemical and Molecular Toxicology
The transient receptor potential ankyrin 1 (TRPA1) channels, characterized as nonselective cation channels with permeability to calcium ions (Ca2 +), are part of the extensive family of transient receptor potential (TRP) channels.
Murat Cakir, Burak Bircan
exaly   +2 more sources