Changes in transient receptor potential vanilloid 1 and transient receptor potential vanilloid 4 in patients with lower urinary tract dysfunction [PDF]
Investigative and Clinical Urology, 2022 Purpose: We investigated the association between transient receptor potential vanilloid (TRPV) expression in human urothelium tissue and lower urinary tract dysfunction (LUTD).
Kang Jun Cho +5 more
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The effects of vanilloid analogues structurally related to capsaicin on the transient receptor potential vanilloid 1 channel [PDF]
Biochemistry and Biophysics Reports, 2022 Transient receptor potential vanilloid 1 (TRPV1) is known as a receptor of capsaicin, a spicy ingredient of chili peppers. It is also sensitive to a variety of pungent compounds and is involved in nociception.
Y. Oka, K. Takahashi, T. Ohta
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Expression profiles of TRPV1, TRPV4, TLR4 and ERK1/2 in the dorsal root ganglionic neurons of a cancer-induced neuropathy rat model [PDF]
PeerJ, 2018 Background The spread of tumors through neural routes is common in several types of cancer in which patients suffer from a moderate-to-severe neuropathy, neural damage and a distorted quality of life.
Ahmad Maqboul, Bakheet Elsadek
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Role of Transient Receptor Potential Vanilloid 1 in Sonic Hedgehog-Dependent Taste Bud Differentiation [PDF]
Life, 2022 Taste bud cell differentiation is extremely important for taste sensation. Immature taste bud cells cannot function during taste perception transmission to the nerve.
Yun-Hee Rhee +8 more
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Transient Receptor Potential Vanilloid 1 Function at Central Synapses in Health and Disease [PDF]
Frontiers in Cellular Neuroscience, 2022 The transient receptor potential vanilloid 1 (TRPV1), a ligand-gated nonselective cation channel, is well known for mediating heat and pain sensation in the periphery. Increasing evidence suggests that TRPV1 is also expressed at various central synapses,
Rodrigo C. Meza +4 more
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A transient receptor potential vanilloid 1-dependent corneal–trigeminal neuroinflammatory circuit promotes corneal neuropathy [PDF]
Experimental and Molecular MedicineCorneal neurosensory abnormalities cause pain and discomfort in ocular surface disease, yet their pathophysiology is poorly understood. Here we show that in a mouse dry eye model, the ocular (over)activation of transient receptor potential vanilloid 1 ...
Manuela Pizzano +10 more
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Riboflavin Inhibits Histamine-Dependent Itch by Modulating Transient Receptor Potential Vanilloid 1 (TRPV1) [PDF]
Frontiers in Molecular Neuroscience, 2021 Riboflavin, also known as vitamin B2, isfound in foods and is used as a dietary supplement. Its deficiency (also called ariboflavinosis) results in some skin lesions and inflammations, such as stomatitis, cheilosis, oily scaly skin rashes, and itchy ...
Kihwan Lee +8 more
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Licorice Extract Isoliquiritigenin Increased Cytosol Calcium and Induced Apoptosis in Colon Cancer Cells via Transient Receptor Potential Vanilloid‐1 [PDF]
Cancer MedicineBackground Colorectal cancer (CRC) is the third most common malignant tumor, and the fifth cause of cancer‐related death in China, while chemotherapy is the primary strategy for CRC.
Lin Wang +3 more
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Molecular Pain, 2017 Transient Receptor Potential Vanilloid 1 (TRPV1) and Transient Receptor Potential Ankyrin 1 (TRPA1) expressed mainly by primary sensory neurons function as major nociceptive integrators.
Noémi Bohonyi +11 more
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In silico analysis of sodium ion permeation mechanisms in transient receptor potential vanilloid 1 [PDF]
Scientific ReportsTransient receptor potential vanilloid 1 (TRPV1) is a non-selective cation channel activated by heat, acidity and chemical ligands. While molecular dynamics simulations have shed some light on the cation permeation processes of TRPV1, the mechanisms in ...
Yuki Nagasato +6 more
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