Results 11 to 20 of about 30,248 (242)

Transient receptor potential vanilloid subtype 1: A potential therapeutic target for fibrotic diseases

open access: yesFrontiers in Physiology, 2022
The transient receptor potential vanilloid subtype 1 (TRPV1), belonging to the TRPV channel family, is a non-selective, calcium-dependent, cation channel implicated in several pathophysiological processes. Collagen, an extracellular matrix component, can
Guangxin Peng   +10 more
doaj   +3 more sources

Role of the transient receptor potential vanilloid 1 in inflammation and sepsis

open access: yesJournal of Inflammation Research, 2011
Isabel Devesa1, Rosa Planells-Cases2, Gregorio Fernández-Ballester1, José Manuel González-Ros1, Antonio Ferrer-Montiel1, Asia Fernández-Carvajal11Instituto de Biología Molecular y Celular ...
Devesa I   +5 more
doaj   +7 more sources

Role of Transient Receptor Potential Vanilloid 1 in Inflammation and Autoimmune Diseases [PDF]

open access: yesPharmaceuticals, 2012
Transient receptor potential vanilloid 1 (TRPV1), a non-selective cation channel, is a receptor activated by high temperatures and chemical agonists such as the vanilloids and protons.
Fumio Tsuji, Hiroyuki Aono
doaj   +3 more sources

Transient Receptor Potential Vanilloid 1 Modulates Central Inflammation in Multiple Sclerosis [PDF]

open access: yesFrontiers in Neurology, 2019
Introduction: Disease course of multiple sclerosis (MS) is negatively influenced by proinflammatory molecules released by activated T and B lymphocytes and local immune cells.
Mario Stampanoni Bassi   +15 more
doaj   +5 more sources

Sensory neuron transient receptor potential vanilloid-1 channel regulates angiogenesis through CGRP in vivo [PDF]

open access: yesFrontiers in Bioengineering and Biotechnology
Angiogenesis plays a key role in bone regeneration. The role of neurons of peripheral nerves involved in angiogenesis of bone defects needs to be explored.
Zhanfeng Zhu   +13 more
doaj   +2 more sources

Direct activation of Transient Receptor Potential Vanilloid 1(TRPV1) by Diacylglycerol (DAG)

open access: yesMolecular Pain, 2008
The capsaicin receptor, known as transient receptor potential channel vanilloid subtype 1 (TRPV1), is activated by a wide range of noxious stimulants and putative ligands such as capsaicin, heat, pH, anandamide, and phosphorylation by protein kinase C ...
Oh Seog   +6 more
doaj   +3 more sources

Osmotic adaptation of nucleus pulposus cells: the role of aquaporin 1, aquaporin 4 and transient receptor potential vanilloid 4 [PDF]

open access: yesEuropean Cells & Materials, 2021
The microenvironment of the nucleus pulposus is hyperosmotic and fluctuates diurnally due to mechanical loading. Changes in extracellular osmolality result in cell volume alterations, responsiveness to such changes is essential for cellular homeostasis ...
JW Snuggs, RAD Bunning, CL Le Maitre
doaj   +1 more source

Inhibition of transient receptor potential vanilloid 1 and transient receptor potential ankyrin 1 by mosquito and mouse saliva. [PDF]

open access: yesPain, 2022
Abstract Arthropods are the largest group of living organisms, and among them, mosquitoes spread parasites and viruses causing deadly diseases. They can easily spread these pathogens because of their painless skin piercing. Although the lack of pain is mainly due to the thinness of their fascicle, it is possible that mosquito saliva ...
Derouiche S   +5 more
europepmc   +4 more sources

Role of Known Transient Receptor Potential Vanilloid Channels in Modulating Cardiac Mechanobiology

open access: yesFrontiers in Physiology, 2021
The transient receptor potential (TRP) channels have been described in almost every mammalian cell type. Several members of the Vanilloid (TRPV) subtype have been found to play important roles in modulating cardiac structure and function through Ca2 ...
Michael Miller   +6 more
doaj   +1 more source

Haemorrhoids and transient receptor potential vanilloid 1 [PDF]

open access: yesGut, 2006
Haemorrhoids are extremely common, and approximately 10 million people are affected by haemorrhoidal disease in the USA.1 Many causes have been proposed to explain the pathogenesis of symptomatic haemorrhoids. The pathophysiological theory, made popular by Thomson’s studies, in which the elastic support of the anal cushions is thought to be broken, is ...
Di Mola F. F.   +6 more
openaire   +3 more sources

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