Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
I. The Use of a Large Conventional Shock Tube as a Pre-Ionizer for an Inverse Pinch Shock Tube. II. The Application of Thin-Film Heat Transfer Gauges and Flush Electrostatic Probes to Partially Ionized Flows in Shock Tubes [PDF]
Part 1. A large diameter (17"), conventional shock tube has been used as the pre-ionizer for an inverse pinch shock tube in an attempt to achieve separation of the shock front and the current sheath in the inverse pinch.
Klein, Alan Frank
core +1 more source
A strategy to introduce multi-gradient structures into iron by explosive shock wave processing
A strategy combining shock-induced phase transition, twins, and dislocations to produce a multi-gradient structure in Fe is designed and proposed by the explosive processing method. A specific emulsion explosive is designed to introduce gradient pressure
Jianian Hu +5 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Psychometric properties of the Transition Shock Scale for Newly Graduated Nurses [PDF]
The purpose of this study was to evaluate psychometric properties and discriminant ability of the Transition Shock Scale for Newly Graduated Nurses developed by Kim et al. (2017).
Kim, Eun-Young
core +1 more source
Spin transition of ferropericlase under shock compression
Planar shock compression experiments are performed at 9–105 GPa on polycrystalline ferropericlase (Mg0.94Fe0.06)O to investigate its Fe2+ spin transition.
N. B. Zhang +7 more
doaj +1 more source
OBLIQUE SHOCK WAVE REFLECTION FROM THE WALL [PDF]
Regular and Mach (irregular) reflection of an oblique shock wave from the wall is considered. Criteria for the transition from regular to irregular reflection are described: von Neumann criterion and the criterion for fixed Mach configuration. Specific
P. V. Bulat +2 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source

