Results 51 to 60 of about 1,664,763 (284)
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Findings of the 2019 Conference on Machine Translation (WMT19) [PDF]
This paper presents the results of the premier shared task organized alongside the Conference on Machine Translation (WMT) 2019. Participants were asked to build machine translation systems for any of 18 language pairs, to be evaluated on a test set of ...
Barrault, Loïc +5 more
core
Literary machine translation under the magnifying glass : assessing the quality of an NMT-translated detective novel on document level [PDF]
Several studies (covering many language pairs and translation tasks) have demonstrated that translation quality has improved enormously since the emergence of neural machine translation systems.
Fonteyne, Margot +2 more
core
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Identification of Fertile Translations in Medical Comparable Corpora: a Morpho-Compositional Approach [PDF]
This paper defines a method for lexicon in the biomedical domain from comparable corpora. The method is based on compositional translation and exploits morpheme-level translation equivalences.
Daille, Béatrice +3 more
core +3 more sources
A Shared Task on Bandit Learning for Machine Translation
We introduce and describe the results of a novel shared task on bandit learning for machine translation. The task was organized jointly by Amazon and Heidelberg University for the first time at the Second Conference on Machine Translation (WMT 2017). The
Danchenko, Pavel +6 more
core +1 more source
Co-Translational Quality Control Induced by Translational Arrest
Genetic mutations, mRNA processing errors, and lack of availability of charged tRNAs sometimes slow down or completely stall translating ribosomes. Since an incomplete nascent chain derived from stalled ribosomes may function anomalously, such as by forming toxic aggregates, surveillance systems monitor every step of translation and dispose of such ...
Yoshitaka Matsuo, Toshifumi Inada
openaire +3 more sources
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Capturing lexical variation in MT evaluation using automatically built sense-cluster inventories [PDF]
The strict character of most of the existing Machine Translation (MT) evaluation metrics does not permit them to capture lexical variation in translation.
Apidianaki, Marianna +2 more
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source

