Results 41 to 50 of about 3,685 (305)

Zrozumieć narzędzia, zrozumieć zawód . O roli kompetencji technicznych we współczesnej praktyce przekładu [PDF]

Linguistische Treffen in Wrocław
The rapid advancement of digital technologies over the past decades has profoundly transformed the nature of language-related professions, redefining both the status and the scope of translator competences. In the field of translation, these changes stem
Magdalena Duś
doaj   +1 more source

Terminological competence in translation [PDF]

Terminology. International Journal of Theoretical and Applied Issues in Specialized Communication, 2009
A Terminology course for Translation students must deal with the role of terminology in the translation process from both a theoretical and practical perspective. The objective of such a course is not to train translators as terminologists or documentation professionals, but rather as language mediators whose job is to facilitate interlinguistic ...
Silvia Montero Martínez, Pamela Faber
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

DeepL y su potencial para el desarrollo de la capacidad de análisis crítico en la clase de traducción inversaDeepL and its potentiality for the development of critical analysis skills in the L1-L2 translation class

Hermeneus, 2021
In our translation classes (Spanish into German) we have observed that students with little experience rely almost blindly on the automatic translator DeepL, encouraged by the company's own motto, which defines it as “the best translator in ...
SILVIA ROISS FRÖSTL, PETRA ZIMMERMANN GONZÁLEZ   +1 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Authentic and simulated project-based learning to improve students’ employability skills and their translator competence

Humanities & Social Sciences Communications
Existing project-based learning (PjBL) literature has not covered the differences between authentic and simulated PjBL effectiveness in improving students’ skills.
Sugeng Hariyanto, Fitrotul Maulidiyah, Achmad Suyono, Urip Sulistiyo, Heather Fehring   +4 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source