Results 51 to 60 of about 56,482 (306)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Developing Communicative and Textual Competence through Genres [PDF]

open access: yes, 2008
In recent years the concept of translation competence has steadily gained acceptance up to the point where it has now become the most widely discussed issue in relation to translator training.
Ezpeleta-Piorno, Pilar   +2 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

TRANSLATING MEDICAL TEXTS FOR LEGAL PURPOSES: A GROWING CHALLENGE FOR COURT TRANSLATORS AND INTERPRETERS [PDF]

open access: yes, 2012
Przekład tekstów medycznych obejmuje cały szereg różnego typu tekstów, takich jak wypisy szpitalne, epikryzy, artykuły naukowe w czasopismach medycznych, ulotki informacyjne dla pacjenta (PILs) czy też wskazówki dotyczące stosowania leku (IFU).
KOŚCIAŁKOWSKA-OKOŃSKA, Ewa
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Eye tracking in translation process research: methodological challenges and solutions [PDF]

open access: yes, 2009
Eye tracking has been eagerly adopted as a technique in translation process research in recent years and, with it, comes a long list of methodological challenges, some of which are specific to translation process research, some of which are more general.
O'Brien, Sharon
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Paradoksy profesjonalizacji. Normy tłumaczeniowe – PN-EN 15038 i PN-EN ISO 17100 – z perspektywy dydaktyki przekładu

open access: yesMiędzy Oryginałem a Przekładem, 2017
Paradoxes of Professionalization: Translation Standards – EN 15038 and EN ISO 17100 – From the Perspective of Translator Education Taking the perspective of translator training, the article discusses the significance of translation standards understood ...
Joanna Dybiec-Gajer
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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