Results 101 to 110 of about 6,019 (214)

Review: A review on classical and atypical scrapie in caprine: Prion protein gene polymorphisms and their role in the disease

Animal, 2016
Scrapie is a naturally occurring transmissible spongiform encephalopathy in sheep and goat. It has been known for ~250 years and is characterised by the accumulation of an abnormal isoform of a host-encoded prion protein that leads to progressive ...
L. Curcio, C. Sebastiani, P. Di Lorenzo, E. Lasagna, M. Biagetti   +4 more
doaj   +1 more source

Spontaneous mutations in the prion protein gene causing transmissible spongiform encephalopathy

, 2002
We analyzed the prion protein gene (PRNP) region in patients with transmissible spongiform encephalopathy associated with the PRNP D178N mutation.
Lee, Hee Suk, Shatunov, Alexey; id_orcid, Dagvadorj, Ayush, Petersen, Robert B, Budka, Herbert, Gambetti, Pierluigi, Cervenakova, Larisa, Goldfarb, Lev G, Brown, Paul   +8 more
core   +1 more source

Comparative studies on the thermostability of five strains of transmissible-spongiform-encephalopathy agent

, 2007
The causal infectious agents of TSEs (transmissible spongiform encephalopathies or prion diseases) are renowned for their resistance to complete inactivation. Survival of TSE infectivity after autoclaving potentially compromises many procedures where TSE
Steele, P J, Somerville, Robert A, Taylor, D M, Fernie, Karen   +3 more
core  

High prevalence of scrapie in a dairy goat herd: tissue distribution of disease-associated PrP and effect of PRNP genotype and age

, 2009
The factors influencing the microstructure of fresh cheese, particularly the particle size, and its reduction by mechanical post-processing, were studied.
Saunders, Ginny, Windl, O., Stuart Martin, Phelan, Laura, Dawson, Michael, Angel Ortiz-Peláez, Timm Konold, Laura Phelan, Martin, Stuart, Hope, James, Ortiz-Pelaez, A., Jeffrey, M., Michael Dawson, Ginny Saunders, Sisó, Sílvia, Dawson, M., James Hope, Stephen A.C. Hawkins, Siso, S., Paula Stewart, Hope, J., Lorenzo González, Wilfred Goldmann, Martin Jeffrey, Phelan, L., Goldmann, W., Martin, S., González, Lorenzo, Goldmann, Wilfred, Windl, Otto, Konold, T., Hawkins, S. A., Saunders, G., Sílvia Sisó, Stewart, Paula, Stewart, P., Gonzalez, L., Otto Windl, Jeffrey, Martin, Konold, Timm, Ortiz-Peláez, Angel, Hawkins, Stephen A.C.   +41 more
core   +1 more source

Review on prion diseases in animals with emphasis to Bovine Spongiform Encephalopathy

Veterinary World, 2012
Prion diseases are known as Transmissible Spongiform Encephalopathies (TSE). These are degenerative brain disorders characterized by tiny microscopic holes that give the brain 'spongy' appearance.
Rajender P. Gupta, Nand K. Mahajan, Mukund S. Londhe, Renu M. Londhe   +3 more
doaj  

Generation of a persistently infected MDBK cell line with natural bovine spongiform encephalopathy (BSE).

PLoS ONE, 2015
Bovine spongiform encephalopathy (BSE) is a zoonotic transmissible spongiform encephalopathy (TSE) thought to be caused by the same prion strain as variant Creutzfeldt-Jakob disease (vCJD).
Dongseob Tark, Hyojin Kim, Michael H Neale, Minjeong Kim, Hyunjoo Sohn, Yoonhee Lee, Insoo Cho, Yiseok Joo, Otto Windl   +8 more
doaj   +1 more source

NEUROPATHOLOGY OF ITALIAN CATS IN FELINE SPONGIFORM ENCEPHALOPATHY SURVEILLANCE

, 2008
Feline spongiform encephalopathy (FSE) is a transmissible spongiform encephalopathy associated with the Consumption of feedstuffs contaminated with tissue from bovine spongiform encephalopathy-affected cattle and characterized by the accumulation in the ...
MANDARA MT, CASTAGNARO, MASSIMO, PORCARIO C, LORIA GR, SALVADORI C, CASALONE C., NEUROPATHOLOGY OF ITALIAN CATS IN FELINE SPONGIFORM ENCEPHALOPATHY SURVEILLANCE IULINI B, MARONI A, CARAMELLI M, CORONA C, MAURELLA C, CANTILE C, PERAZZINI AZ   +12 more
core  

Variability in disease phenotypes within a single PRNP genotype suggests the existence of multiple natural sheep scarpie strains within Europe

, 2010
Variability of pathological phenotypes within classical sheep scrapie cases has been reported for some time, but in many instances it has been attributed to differences in the PRNP genotype of the host.
González, L., E. Monleon, L. J. M. van Keulen, Jeffrey, M., Balkema-Buschmann, A., C. Hoffmann, Badiola, J.J., Lulini, B., Keulen, L.J.M., van, van Keulen, L.J.M., A. Balkema-Buschmann, Monleón, E., S. Siso, A. Ortiz-Pelaez, Langeveld, J.P.M., Hoffmann, C., J. J. Badiola, Sisó, S., Acín, C., Ortiz-Peláez, A., J. P. M. Langeveld, B. Iulini, M. Jeffrey, L. Gonzalez, C. Casalone, Casalone, C., C. Acin   +26 more
core   +1 more source

Corrigendum: The Role of the Gut Microbiota in the Pathogenesis of Parkinson's Disease

Frontiers in Neurology, 2020
Dongming Yang, Deming Zhao, Syed Zahid Ali Shah, Wei Wu, Mengyu Lai, Xixi Zhang, Jie Li, Zhiling Guan, Huafen Zhao, Wen Li, Hongli Gao, Xiangmei Zhou, Lifeng Yang   +12 more
doaj   +1 more source

Susceptibilities of Nonhuman Primates to Chronic Wasting Disease

Emerging Infectious Diseases, 2009
Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy, or prion disease, that affects deer, elk, and moose. Human susceptibility to CWD remains unproven despite likely exposure to CWD-infected cervids.
Brent Race, Kimberly D. Meade-White, Michael W. Miller, Kent D. Barbian, Richard Rubenstein, Giuseppe LaFauci, Larisa Cervenakova, Cynthia Favara, Donald Gardner, Dan Long, Michael Parnell, James Striebel, Suzette A. Priola, Anne Ward, Elizabeth S. Williams, Richard Race, Bruce Chesebro   +16 more
doaj   +1 more source