Results 81 to 90 of about 20,782 (249)

Irisin regulates oxidative stress and mitochondrial dysfunction through the UCP2-AMPK pathway in prion diseases

Cell Death and Disease
Prion diseases are a group of fatal neurodegenerative disorders characterized by the abnormal folding of cellular prion proteins into pathogenic forms.
Pei Wen, Zhixin Sun, Dongming Yang, Jie Li, Zhiping Li, Mengyang Zhao, DongDong Wang, Fengting Gou, Jingjing Wang, Yuexin Dai, Deming Zhao, Lifeng Yang   +11 more
doaj   +1 more source

Kuru: A Journey Back in Time from Papua New Guinea to the Neanderthals’ Extinction

Pathogens, 2013
Kuru, the first human transmissible spongiform encephalopathy was transmitted to chimpanzees by D. Carleton Gajdusek (1923–2008). In this review, I briefly summarize the history of this seminal discovery along its epidemiology, clinical picture ...
Pawel P. Liberski
doaj   +1 more source

Transmission of sheep‑bovine spongiform encephalopathy to pigs [PDF]

, 2016
Experimental transmission of the bovine spongiform encephalopathy (BSE) agent has been successfully reported in pigs inoculated via three simultaneous distinct routes (intracerebral, intraperitoneal and intravenous).
Acín, Cristina, Andreoletti, Olivier, Badiola, Juan José, Bolea, Rosa, Cobrière, Fabien, Filali, Hicham, Hedman, Carlos, Marín, Belén, Moreno, Bernardino, Pitarch, José Luis, Pumarola i Batlle, Martí, Vargas, Antonia, Vazquez, Francisco   +12 more
core   +7 more sources

The Effectiveness of Postharvest Processing on Microbiological Safety of Game Meat—A Systematic Review

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 2, March 2026.
ABSTRACT The rising global consumption of game meat has highlighted gaps in the management of biological hazards associated with its production and consumption, and the safety of processed game meat products remain insufficiently addressed. Therefore, there is a need for research evaluating the effectiveness of processing and preservation methods in ...
Naim Deniz Ayaz, Ali Aydin, Ewa Bilska‐Zając, Raffaella Branciari, Gunita Deksne, Vangelis Economou, Bożena Futoma‐Kołoch, Robert Głogowski, Eduarda Gomes Neves, Famke Jansen, Weronika Korpysa‐Dzirba, Andrea Lauková, Thomai Lazou, Guðný Rut Pálsdóttir, Maria Francesca Peruzy, Petras Prakas, David Ranucci, Rossana Roila, Mirosław Różycki, Selene Rubiola, Ioannis Sakaridis, Madalena Vieira‐Pinto   +21 more
wiley   +1 more source

High Titers of Transmissible Spongiform Encephalopathy Infectivity Associated with Extremely Low Levels of PrPSc in Vivo*

Journal of Biological Chemistry, 2007
Diagnosis of transmissible spongiform encephalopathy (TSE) disease in humans and ruminants relies on the detection in post-mortem brain tissue of the protease-resistant form of the host glycoprotein PrP.
R. Barron, S. Campbell, Declan King, A. Bellon, E. Karen, Chapman, R. Williamson, J. Manson   +7 more
semanticscholar   +1 more source

Epidemiology of progressive intellectual and neurological deterioration in UK children

Developmental Medicine &Child Neurology, Volume 68, Issue 3, Page 418-428, March 2026.
This study of PIND in UK children was carried out via the British Paediatric Surveillance Unit from 1997 to 2024. It identified six cases of vCJD. 2367 children had other diagnoses explain their deterioration. There were 259 other diseases in the diagnosed group.
Christopher M. Verity, Polly J. Maunder, Anne Marie Winstone, Suvankar Pal   +3 more
wiley   +1 more source

Sheep Feed and Scrapie, France

Emerging Infectious Diseases, 2005
Scrapie is a small ruminant, transmissible spongiform encephalopathy (TSE). Although in the past scrapie has not been considered a zoonosis, the emergence of bovine spongiform encephalopathy, transmissible to humans and experimentally to sheep, indicates
Sandrine Philippe, Christian Ducrot, Pascal Roy, Laurent Remontet, Nathalie Jarrige, Didier Calavas   +5 more
doaj   +1 more source

Intraspecific Contact Among White‐Tailed Deer: A Literature Review and Chronic Wasting Disease Case Study

Ecology and Evolution, Volume 16, Issue 2, February 2026.
We identified five themes underlying research on intraspecific contact among white‐tailed deer: physical touch, social groups, spatial overlap, contact rates, and social networks. We found white‐tailed deer infected with chronic wasting disease exhibited similar rates of intraspecific contact as those without infections.
Nathaniel H. Wehr, Kristin J. Bondo, Christopher S. Rosenberry, David Stainbrook, Bret D. Wallingford, W. David Walter   +5 more
wiley   +1 more source

Characterization of Thermodynamic Diversity between Transmissible Spongiform Encephalopathy Agent Strains and Its Theoretical Implications*

Journal of Biological Chemistry, 2002
Some transmissible spongiform encephalopathy (TSE) (or “prion”) strains, notably those derived from bovine spongiform encephalopathy, are highly resistant to total inactivation by heat.
R. Somerville, R. Oberthür, U. Havekost, F. Macdonald, David M. Taylor, A. Dickinson   +5 more
semanticscholar   +1 more source

Sustainable bioceramics, biopolymers, and composites for bone applications: From bench to production

International Journal of Applied Ceramic Technology, Volume 23, Issue 1, February 2026.
Abstract In response to environmental challenges and primary resource scarcity, sustainable approaches that rely on recycling and reusing waste materials are becoming highly valuable and appealing options in modern society. These strategies have started being applied in biomaterials science, too, leading to the advent of new synergies between ...
Bohan Zhang, Francesco Baino
wiley   +1 more source