Results 71 to 80 of about 6,019 (214)

HaloTag Fusion Enables Dynamic Analysis of Prion Protein Biosynthesis, Turnover, and Misfolding

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Prion protein (PrP) misfolding underlies fatal neurodegenerative diseases. We developed a HaloTag‐based PrP fusion enabling spatiotemporal labeling of distinct PrP populations in living cells. This system recapitulates native PrP biology, reveals early misfolding events in disease‐associated mutants, and allows mechanistic interrogation of PrP‐lowering
Antonio Masone, Eleonora Busani, Roberto Chiesa   +2 more
wiley   +1 more source

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

MedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu, Lin Jia, Kerong Wu, Mo Chen, Jichao Sun, Chuanbin Yang, Chengchao Xu, Jie Sun, Jigang Wang, Lingyun Dai   +9 more
wiley   +1 more source

Different forms of the bovine PrP gene have five or six copies of a short, G-C-rich element within the protein-coding exon

, 1991
Current models of the virus-like agents of scrapie and bovine spongiform encephalopathy (BSE) have to take into account that structural changes in a host-encoded protein (PrP protein) exhibit an effect on the time course of these diseases and the ...
Dawson, M, Hunter, N., Martin, T., Hunter, N, Goldmann, W., Goldmann, W, Dawson, M., Hope, J, Hope, J., Martin, T   +9 more
core   +1 more source

Sheep Feed and Scrapie, France

Emerging Infectious Diseases, 2005
Scrapie is a small ruminant, transmissible spongiform encephalopathy (TSE). Although in the past scrapie has not been considered a zoonosis, the emergence of bovine spongiform encephalopathy, transmissible to humans and experimentally to sheep, indicates
Sandrine Philippe, Christian Ducrot, Pascal Roy, Laurent Remontet, Nathalie Jarrige, Didier Calavas   +5 more
doaj   +1 more source

Mimicking the Ocean: Critical Challenges in Scaffold Design and Tissue Texturization for Cell‐Cultured Seafood

Journal of Food Science, Volume 91, Issue 6, June 2026.
ABSTRACT Cellular aquaculture offers a sustainable solution to global seafood demand, yet the production of high‐value, whole‐cut fillets is hindered by the “texture gap,” the inability to replicate the complex, anisotropic architecture of native fish muscle and its collagenous myosepta.
Mustafa Öz, Enes Üstüner
wiley   +1 more source

Review on the epidemiology and dynamics of BSE epidemics

, 2008
The paper describes how the comprehensive surveillance of bovine spongiform encephalopathy (BSE) and studies carried out on these data has enhanced our knowledge of the epidemiology of BSE.
Ducrot, C., Heim, D., Koeijer, A.A., de, Arnold, M., Calavas, D.   +4 more
core   +1 more source

3D‐printing of Methacryloylated Recombinant Collagen for Tissue Engineering

ChemistrySelect, Volume 11, Issue 17, 5 May 2026.
Recombinant collagen‐like proteins offer promise as alternatives to mammalian collagens. There is less risk of disease transfer, and changes in structure can be readily introduced. Here, a recombinant collagen‐like protein was methacryloylated for extrusion printing and rapid photo‐crosslinking.
Malachy K. Maher, Veronica Glattauer, Zhilian Yue, Timothy C. Hughes, Carmine Onofrillo, Serena Duchi, John A. M. Ramshaw, Gordon G. Wallace   +7 more
wiley   +1 more source

A rapid dual staining procedure for the quantitative discrimination of prion amyloid from tissues reveals how interactions between amyloid and lipids in tissue homogenates may hinder the detection of prions

, 2009
Transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative diseases with no cure to this day, and are often associated with the accumulation of amyloid plaques in the brain and other tissues in affected individuals. The emergence of new
Keevil, C.William, Collin, R., Hervé, R., Secker, Thomas, Pinchin, H.E.   +4 more
core   +1 more source

Phenotypic Similarity of Transmissible Mink Encephalopathy in Cattle and L-type Bovine Spongiform Encephalopathy in a Mouse Model

Emerging Infectious Diseases, 2007
Transmissible mink encepholapathy (TME) is a foodborne transmissible spongiform encephalopathy (TSE) of ranch-raised mink; infection with a ruminant TSE has been proposed as the cause, but the precise origin of TME is unknown.
Thierry G.M. Baron, Anna Bencsik, Anne-Gaëlle Biacabe, Eric Morignat, Richard A. Bessen   +4 more
doaj   +1 more source

Are Insects a Feasible Option or Just a Hyped Promise in Ruminant Nutrition? A Systematic Review of What Has Been Done and What Lies Ahead

Veterinary Medicine and Science, Volume 12, Issue 3, May 2026.
Insects are emerging as sustainable alternatives for ruminants. This systematic review evaluates in vitro and in vivo evidence on insect‐based feeds in ruminant nutrition, discussing their outcomes and elucidating underlying mechanisms. Despite promising effects on rumen fermentation, growth, and product quality, inconsistencies related to insect ...
Navid Ghavipanje, Manuel Gonzalez‐Ronquillo, Manuela Renna, Agustín Corral‐Luna, Ahmed Eid Kholif, Mohammad Hasan Fathi Nasri, Einar Vargas‐Bello‐Pérez   +6 more
wiley   +1 more source