Results 71 to 80 of about 4,885 (171)

Overexpression of mouse prion protein in transgenic mice causes a non-transmissible spongiform encephalopathy. [PDF]

open access: yesSci Rep, 2022
Jackson GS   +5 more
europepmc   +1 more source

Prion remains infectious after passage through digestive system of American crows (Corvus brachyrhynchos).

open access: yesPLoS ONE, 2012
Avian scavengers, such as American crows (Corvus brachyrhynchos), have potential to translocate infectious agents (prions) of transmissible spongiform encephalopathy (TSE) diseases including chronic wasting disease, scrapie, and bovine spongiform ...
Kurt C VerCauteren   +4 more
doaj   +1 more source

Transmissible Spongiform Encephalopathies [PDF]

open access: yes, 2012
Neuronal death represents the primary pathology of neurodegenerative diseases such as Alzheimer's and Parkinson’s disease and Amyotrophic Lateral Sclerosis. These diseases usually present with a slow onset and a chronic progression. Various regions of the brain, spinal cord, or peripheral nerves may be affected, leading to functional impairment and ...
Glaucia N. M. Hajj   +3 more
openaire   +1 more source

Phenotype shift from atypical scrapie to CH1641 following experimental transmission in sheep.

open access: yesPLoS ONE, 2015
The interactions of host and infecting strain in ovine transmissible spongiform encephalopathies are known to be complex, and have a profound effect on the resulting phenotype of disease.
Marion M Simmons   +6 more
doaj   +1 more source

Molecular Typing of Protease-Resistant Prion Protein in Transmissible Spongiform Encephalopathies of Small Ruminants, France, 2002–2009

open access: yesEmerging Infectious Diseases, 2011
The agent that causes bovine spongiform encephalopathy (BSE) may be infecting small ruminants, which could have serious implications for human health. To distinguish BSE from scrapie and to examine the molecular characteristics of the protease-resistant ...
Johann Vulin   +4 more
doaj   +1 more source

Review: A review on classical and atypical scrapie in caprine: Prion protein gene polymorphisms and their role in the disease

open access: yesAnimal, 2016
Scrapie is a naturally occurring transmissible spongiform encephalopathy in sheep and goat. It has been known for ~250 years and is characterised by the accumulation of an abnormal isoform of a host-encoded prion protein that leads to progressive ...
L. Curcio   +4 more
doaj   +1 more source

Review on prion diseases in animals with emphasis to Bovine Spongiform Encephalopathy

open access: yesVeterinary World, 2012
Prion diseases are known as Transmissible Spongiform Encephalopathies (TSE). These are degenerative brain disorders characterized by tiny microscopic holes that give the brain 'spongy' appearance.
Rajender P. Gupta   +3 more
doaj  

Corrigendum: The Role of the Gut Microbiota in the Pathogenesis of Parkinson's Disease

open access: yesFrontiers in Neurology, 2020
Dongming Yang   +12 more
doaj   +1 more source

Generation of a persistently infected MDBK cell line with natural bovine spongiform encephalopathy (BSE).

open access: yesPLoS ONE, 2015
Bovine spongiform encephalopathy (BSE) is a zoonotic transmissible spongiform encephalopathy (TSE) thought to be caused by the same prion strain as variant Creutzfeldt-Jakob disease (vCJD).
Dongseob Tark   +8 more
doaj   +1 more source

Human transmissible spongiform encephalopathy: Case report

open access: yesIatreia, 2014
We report the case of a 64 year-old woman with motor and cognitive deterioration that progressed rapidly during eight months. She was unsuccessfully treated with quinacrine, and died in a terminal status, by septic shock secondary to bronchopneumonia by ...
Duque Velásquez, Camilo   +6 more
doaj  

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