Results 61 to 70 of about 20,782 (249)
We examined changes in perceived risks associated with chronic wasting disease (CWD) and perceived trust in wildlife agencies over time across 10 studies in eight states. Results indicated that perceived risks to both deer and humans declined the longer the disease had been in a state. Results also indicated that agency trust evaluations were positive,
Jerry J. Vaske, Craig A. Miller
wiley +1 more source
Molecular Discrimination of Sheep Bovine Spongiform Encephalopathy from Scrapie
Sheep CH1641-like transmissible spongiform encephalopathy isolates have shown molecular similarities to bovine spongiform encephalopathy (BSE) isolates. We report that the prion protein PrPSc from sheep BSE is extremely resistant to denaturation.
Laura Pirisinu +9 more
doaj +1 more source
PrPCWD lymphoid cell targets in early and advanced chronic wasting disease of mule deer [PDF]
Up to 15% of free-ranging mule deer in northeastern Colorado and southeastern Wyoming, USA, are afflicted with a prion disease, or transmissible spongiform encephalopathy (TSE), known as chronic wasting disease (CWD).
Barillas-Mury, C. +6 more
core +2 more sources
Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga +11 more
wiley +1 more source
European red deer (Cervus elaphus elaphus) are susceptible to the agent of bovine spongiform encephalopathy, one of the transmissible spongiform encephalopathies, when challenged intracerebrally but their susceptibility to alimentary challenge, the ...
Mark P Dagleish +15 more
doaj +1 more source
Final results of project on feline spongiform encephalopathy [PDF]
Feline spongiform encephalopathy (FSE) is a transmissible spongiform encephalopathy associated with the accumulation of an abnormal isoform of the prion protein (PrPsc) in the Central Nervous System. This research allowed to identify other neurological
Cantile, Carlo +9 more
core
Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley +1 more source
Isolation of Prion with BSE Properties from Farmed Goat
Transmissible spongiform encephalopathies are fatal neurodegenerative diseases that include variant Creutzfeldt-Jakob disease in humans, scrapie in small ruminants, and bovine spongiform encephalopathy (BSE) in cattle.
John Spiropoulos +7 more
doaj +1 more source
Emerging infectious diseases: coping with uncertainty [PDF]
The world’s scientific community must be in a state of constant readiness to address the threat posed by newly emerging infectious diseases. Whether the disease in question is SARS in humans or BSE in animals, scientists must be able to put into action ...
Cummings, L
core +1 more source
Prnp Deletion Mitigates Muscle Fiber Type‐Specific Sarcopenia Induced by Prion Infection in Mice
ABSTRACT Recent studies have shown that significant expression of PrPC protein is also present in skeletal muscle, and it plays a significant role in maintaining skeletal muscle homeostasis. Although the expression of PrPC in skeletal muscle has been clarified, the effects of PrPSc‐mediated prion protein infection on sarcopenia in mice and its ...
Wenduo Liu +6 more
wiley +1 more source

