Results 41 to 50 of about 20,782 (249)
Frontiers in Aging Neuroscience, 2017 Prion diseases are neurodegenerative pathologies characterized by the accumulation of a protease-resistant form of the cellular prion protein named prion protein scrapie (PrPSc) in the brain. PrPSc accumulation in the endoplasmic reticulum (ER) result in
Lifeng Yang +3 more
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Pathogenetical significance of porencephalic lesions associated with intracerebral inoculation of sheep with the bovine spongiform encephalopathy (BSE) agent [PDF]
, 2009 Decreased rates of transmission of transmissible spongiform encephalopathies (TSEs) to sheep have been attributed to some polymorphisms of the prion protein (PrP) and to a ‘species barrier’ on interspecies experiments.
Card +21 more
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Frontiers in Cellular and Infection Microbiology, 2017 Mycobacterium bovis (M. bovis) is the pathogen of animals and humans that can replicate in the phagosomes of myeloid cells. Cytosolic detection of bacterial products plays a crucial role in initiating the innate immune response, including autophagy ...
Liu Chunfa +6 more
doaj +1 more source
Methods for differentiating prion types in food-producing animals [PDF]
, 2015 Prions are an enigma amongst infectious disease agents as they lack a genome yet confer specific pathologies thought to be dictated mainly, if not solely, by the conformation of the disease form of the prion protein (PrPSc).
Gough, Kevin C. +3 more
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Molecular Dynamics Studies on the Buffalo Prion Protein [PDF]
, 2015 It was reported that buffalo is a low susceptibility species resisting to prion diseases, which are invariably fatal and highly infectious neurodegenerative diseases that affect a wide variety of species.
Chatterjee, Subhojyoti +2 more
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Neuropathological and molecular comparison between clinical and asymptomatic bovine spongiform encephalopathy cases [PDF]
, 2018 Interest in the proper neuropathological and molecular characterization of bovine spongiform encephalopathy (BSE) has increased since asymptomatic and atypical cases were detected in the cattle population by active disease surveillance.
Sisó, Silvia +6 more
core +2 more sources
Advanced survival models for risk-factor analysis in scrapie [PDF]
, 2007 Because of the confounding effects of long incubation duration and flock management, accurate epidemiological studies of scrapie outbreaks are difficult to carry out.
Andréoletti, Olivier +6 more
core +4 more sources
The Molecular Pathology of Prion Diseases [PDF]
, 2004 Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of invariably fatal neurodegenerative disorders. Uniquely, they may present as sporadic, inherited, or infectious forms, all of which involve conversion of the normal ...
Herms, Jochen +2 more
core
Coping with uncertainty in public health: the use of heuristics [PDF]
, 2014 The observation that experts and lay people use cognitive shortcuts or heuristics to arrive at judgements about complex problems is certainly not new.
Bond +7 more
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Harvest increase and culling as tools for managing chronic wasting disease in white‐tailed deer
The Journal of Wildlife Management, EarlyView.We used an agent‐based model to simulate the effect of CWD management on a white‐tailed deer population in northwest Indiana and northeast Illinois. Our results suggest that wildlife managers should reconsider how and if they should manage CWD. Abstract Chronic wasting disease (CWD), a transmissible spongiform encephalopathy that affects white‐tailed ...
Jonathan D. Brooks +3 more
wiley +1 more source