Results 41 to 50 of about 75,114 (212)
A study of the incubation period, or age at onset, of the transmissible spongiform encephalopathies/prion diseases. [PDF]
In order to model epidemics of infectious diseases, particularly to estimate probable numbers of cases with onset at any particular time, it is necessaiy to incorporate a term for the incubation period frequency distribution. Sartwell's hypothesis states
Wooldridge, Marion Joan Anstee
core +1 more source
Transmissible Spongiform Encephalopathies in Humans [PDF]
Annual Review of Microbiology, 1999 ▪ Abstract Creutzfeldt-Jakob disease (CJD), the first transmissible spongiform encephalopathy (TSE) to be described in humans, occurs in a sporadic, familial, or iatrogenic form. Other TSEs in humans, shown to be associated with specific prion protein gene mutations, have been reported in different parts of the world.
openaire +3 more sources
Different forms of the bovine PrP gene have five or six copies of a short, G-C-rich element within the protein-coding exon [PDF]
, 1991 Current models of the virus-like agents of scrapie and bovine spongiform encephalopathy (BSE) have to take into account that structural changes in a host-encoded protein (PrP protein) exhibit an effect on the time course of these diseases and the ...
Dawson, M +9 more
core +1 more source
Review on the epidemiology and dynamics of BSE epidemics [PDF]
, 2008 The paper describes how the comprehensive surveillance of bovine spongiform encephalopathy (BSE) and studies carried out on these data has enhanced our knowledge of the epidemiology of BSE.
Ducrot, C. +4 more
core +1 more source
Do More Open Economies Export Less Diversely in Brazilian Agribusiness?
Agribusiness, EarlyView.ABSTRACT This paper asks whether municipalities with a larger export‐to‐revenue ratio display a more concentrated bundle of exported goods in Brazilian agribusiness. Recent advances in export imputation for Brazilian municipalities allow for an analysis of the concentration profile of each municipality and its association with export openness.
Alan Leal, Michelle Marcia Viana Martins
wiley +1 more source
American Journal of Agricultural Economics, EarlyView.Abstract Our general interest is in global trade loss from livestock pathogens, specifically exports. We adopt a causal inference approach that considers animal disease outbreaks over time as non‐staggered binary treatments with the potential for switching in (infection) and out of treatment (recovery) within the sample period. The outcome evolution of
Mohammad Maksudur Rahman +1 more
wiley +1 more source
An overview of animal prion diseases
Virology Journal, 2011 Prion diseases are transmissible neurodegenerative conditions affecting human and a wide range of animal species. The pathogenesis of prion diseases is associated with the accumulation of aggregates of misfolded conformers of host-encoded cellular prion ...
Imran Muhammad, Mahmood Saqib
doaj +1 more source
Levels of the Mahogunin Ring Finger 1 E3 ubiquitin ligase do not influence prion disease. [PDF]
PLoS ONE, 2013 Prion diseases are rare but invariably fatal neurodegenerative disorders. They are associated with spongiform encephalopathy, a histopathology characterized by the presence of large, membrane-bound vacuolar structures in the neuropil of the brain.
Derek Silvius +8 more
doaj +1 more source
microRNA-146a as a biomarker for transmissible spongiform encephalopathy
Folia Neuropathologica, 2022 The pro-inflammatory, innate-immune system ribonucleic acid mediator microRNA-146a, constitutively expressed in the brain and central nervous system (CNS) of both the mouse and the human, is pathologically up-regulated in multiple transmissible ...
Aileen Pogue, Yuhai Zhao, Walter Lukiw
doaj +1 more source
American Journal of Industrial Medicine, EarlyView.ABSTRACT Background Exposures to human pathogens and toxins in licensed facilities in Canada have been monitored by a federal surveillance system since 2015, yet the affected persons (APs) in these incidents remain uncharacterized. This study comprehensively describes APs, highlighting sector‐specific patterns and trends over time.
Emily F. Tran +4 more
wiley +1 more source