Results 31 to 40 of about 75,114 (212)

Atypical status of bovine spongiform encephalopathy in Poland: a molecular typing study [PDF]

, 2008
The aim of this study was to analyze molecular features of protease-resistant prion protein (PrPres) in Western blots of BSE cases diagnosed in Poland with respect to a possible atypical status.
Polak, M.P., Zmudzinski, J.F., Jacobs, J.G., Langeveld, J.P.M.   +3 more
core   +1 more source

MicroRNA 27a-3p Regulates Antimicrobial Responses of Murine Macrophages Infected by Mycobacterium avium subspecies paratuberculosis by Targeting Interleukin-10 and TGF-β-Activated Protein Kinase 1 Binding Protein 2

Frontiers in Immunology, 2018
Mycobacterium avium subspecies paratuberculosis (MAP) persistently survive and replicate in mononuclear phagocytic cells by adopting various strategies to subvert host immune response.
Tariq Hussain, Deming Zhao, Syed Zahid Ali Shah, Jie Wang, Ruichao Yue, Yi Liao, Naveed Sabir, Lifeng Yang, Xiangmei Zhou   +8 more
doaj   +1 more source

Pruritus is a common feature in sheep infected with the BSE agent. [PDF]

, 2008
BACKGROUND: The variability in the clinical or pathological presentation of transmissible spongiform encephalopathies (TSEs) in sheep, such as scrapie and bovine spongiform encephalopathy (BSE), has been attributed to prion protein genotype, strain ...
Vidal-Diez, Alberto, Chaplin, Melanie J., Simmons, MM, Marion M Simmons, Chaplin, Melani J., Dexter, Glenda, Vidal-Diez, A, Martin Jeffrey, Christine Berthelin-Baker, Bone Gemma, Melanie J Chaplin, Glenda Dexter, Konold Timm, Tortosa Méndez, Raül, Peter Hill, Simmons Marion M, Simmons, Marion M., Tortosa Raul, Chaplin Melanie J, Davis Andrew, Berthelin-Baker, C, Bellworthy, SJ, Dexter Glenda, Bellworthy Susan J, Chaplin, MJ, Susan J Bellworthy, Bellworthy, Susan J., Timm Konold, Hill, P, Berthelin-Baker Christine, Gemma Bone, Raul Tortosa, Tortosa, R, Vidal-Diez Alberto, Jeffrey Martin, Hill, Peter, Konold, T, Hill Peter, Tortosa, Raul, Berthelin-Baker, Christine, Dexter, G, Davis, Andrew, Bone, G, Davis, A, Vidal Díez, Alberto, Jeffrey, M, Bone, Gemma, Jeffrey, Martin, Konold, Timm, Andrew Davis, Alberto Vidal-Diez   +50 more
core   +1 more source

BSE infectivity in jejunum, ileum and ileocaecal junction of incubating cattle [PDF]

, 2011
To establish bovine spongiform encephalopathy (BSE) public health protection measures it is important to precisely define the cattle tissues considered as specified risk materials (SRM).
Rogers Ron, Ziegler Ute, Ziegler, U., Groschup, Martin H., Keller, M., van Keulen Lucien, Eiden, M., Hoffmann Christine, Eiden, Martin, Keller Markus, Eiden Martin, Bob Hills, Hills Bob, Christine Hoffmann, Jorg G Jacobs, Balkema-Buschmann, A., Van Keulen, L., Martin Kaatz, Ziegler, Ute, Ute Ziegler, Keulen, L., Van, Jacobs, J.G., Balkema-Buschmann Anne, Rogers, R., Keller, Markus, Groschup Martin H, Hoffmann, C., Hills, B., Lucien van Keulen, Balkema-Buschmann, Anne, Markus Keller, Martin Eiden, Kaatz, Martin, Fast, Christine, Anne Balkema-Buschmann, Kaatz Martin, Groschup, M.H., Martin H Groschup, Jacobs Jorg G, Kaatz, M., Ron Rogers   +40 more
core   +1 more source

MicroRNA-199a Inhibits Cellular Autophagy and Downregulates IFN-β Expression by Targeting TBK1 in Mycobacterium bovis Infected Cells

Frontiers in Cellular and Infection Microbiology, 2018
The mechanism by which microRNAs (miRNAs) modulate innate immunity and autophagy has not been fully elucidated in Mycobacterium bovis (M. bovis) infections. In this study, we identified that miR-199a inhibited key innate immune responses and autophagy in
Jie Wang, Tariq Hussain, Ruichao Yue, Yi Liao, Qiang Li, Jiao Yao, Yinjuan Song, Xin Sun, Nan Wang, Lei Xu, Srinand Sreevatsan, Deming Zhao, Xiangmei Zhou   +12 more
doaj   +1 more source

Prion diseases are efficiently transmitted by blood transfusion in sheep [PDF]

, 2008
The emergence of variant Creutzfeld-Jakob disease, following on from the bovine spongiform encephalopathy (BSE) epidemic, led to concerns about the potential risk of iatrogenic transmission of disease by blood transfusion and the introduction of costly ...
Foster, J., Hunter, N., Goldmann, W., Chong, A., Gonzalez, L., Siso, S., Houston, F., McCutcheon, S., Jeffrey, M.   +8 more
core   +1 more source

The Role of Unfolded Protein Response and Mitogen-Activated Protein Kinase Signaling in Neurodegenerative Diseases with Special Focus on Prion Diseases

Frontiers in Aging Neuroscience, 2017
Prion diseases are neurodegenerative pathologies characterized by the accumulation of a protease-resistant form of the cellular prion protein named prion protein scrapie (PrPSc) in the brain. PrPSc accumulation in the endoplasmic reticulum (ER) result in
Lifeng Yang, Syed Zahid Ali Shah, Deming Zhao, Tariq Hussain   +3 more
doaj   +1 more source

The Central Role of IFI204 in IFN-β Release and Autophagy Activation during Mycobacterium bovis Infection

Frontiers in Cellular and Infection Microbiology, 2017
Mycobacterium bovis (M. bovis) is the pathogen of animals and humans that can replicate in the phagosomes of myeloid cells. Cytosolic detection of bacterial products plays a crucial role in initiating the innate immune response, including autophagy ...
Liu Chunfa, Sun Xin, Li Qiang, Srinand Sreevatsan, Lifeng Yang, Deming Zhao, Xiangmei Zhou   +6 more
doaj   +1 more source

Transmissible spongiform encephalopathies in Australia

Communicable Diseases Intelligence, 2001
The Australian National Creutzfeldt-Jakob Disease Registry (ANCJDR) commenced surveillance in September 1993 as part of the Commonwealth's response to 4 cases of pituitary hormone (gonadotrophin)-associated Creutzfeldt-Jakob disease (CJD). With the passage of time, the Registry has become responsible for ascertaining all human transmissible spongiform ...
A, Boyd, A, Fletcher, J S, Lee, V, Lewis, C L, Masters, S J, Collins   +5 more
openaire   +2 more sources

High titers of transmissible spongiform encephalopathy infectivity associated with extremely low levels of PrP in vivo [PDF]

, 2007
Rona Barron - ORCID: 0000-0003-4512-9177 https://orcid.org/0000-0003-4512-9177Diagnosis of transmissible spongiform encephalopathy (TSE) disease in humans and ruminants relies on the detection in post-mortem brain tissue of the protease-resistant form of
Williamson, R. A., Manson, Jean C., Barron, R. M., Campbell, Susan L., Manson, J., King, Declan, Chapman, K. E., Barron, Rona, Bellon, Anne, Chapman, Karen E., Bellon, A., Williamson, R. Anthony, Campbell, S. L.   +12 more
core   +1 more source