Results 1 to 10 of about 76,764 (112)

Factors Associated With Newly HIV Infection and Transmitted Drug Resistance Among Men Who Have Sex With Men in Harbin, P.R. China [PDF]

Frontiers in Public Health, 2022
BackgroundThis study aimed to evaluate HIV incidence, factors associated with HIV incidence and transmitted drug resistance (TDR) among newly infected men who have sex with men (MSM) in Harbin, P.R.
Shan Hui, Shan Hui, Fangfang Chen, Yi Li, Yan Cui, Jinhui Zhang, Ling Zhang, Yisi Yang, Yanlin Liu, Yashuang Zhao, Fan Lv   +10 more
doaj   +2 more sources

Transmitted drug resistance among HIV-1 drug-naïve patients in Greece

International Journal of Infectious Diseases, 2021
Objectives: Despite the success of antiretroviral treatment (ART), the persisting transmitted drug resistance (TDR) and HIV genetic heterogeneity affect the efficacy of treatment.
Maria Kantzanou, Maria A. Karalexi, Helen Papachristou, Alexis Vasilakis, Chrysoula Rokka, Antigoni Katsoulidou   +5 more
doaj   +3 more sources

Drug resistance mutations for surveillance of transmitted HIV-1 drug-resistance: 2009 update. [PDF]

PLoS ONE, 2009
Programs that monitor local, national, and regional levels of transmitted HIV-1 drug resistance inform treatment guidelines and provide feedback on the success of HIV-1 treatment and prevention programs.
Diane E Bennett, Ricardo J Camacho, Dan Otelea, Daniel R Kuritzkes, Hervé Fleury, Mark Kiuchi, Walid Heneine, Rami Kantor, Michael R Jordan, Jonathan M Schapiro, Anne-Mieke Vandamme, Paul Sandstrom, Charles A B Boucher, David van de Vijver, Soo-Yon Rhee, Tommy F Liu, Deenan Pillay, Robert W Shafer   +17 more
doaj   +3 more sources

Increasing Prevalence of HIV-1 Transmitted Drug Resistance in Portugal: Implications for First Line Treatment Recommendations [PDF]

Viruses, 2020
Introduction: Treatment for All recommendations have allowed access to antiretroviral (ARV) treatment for an increasing number of patients. This minimizes the transmission of infection but can potentiate the risk of transmitted (TDR) and acquired drug ...
Marta Pingarilho, Victor Pimentel, Isabel Diogo, Sandra Fernandes, Mafalda Miranda, Andrea Pineda-Pena, Pieter Libin, Kristof Theys, M. Rosário O. Martins, Anne-Mieke Vandamme, Ricardo Camacho, Perpétua Gomes, Ana Abecasis, on behalf of the Portuguese HIV-1 Resistance Study Group   +13 more
doaj   +2 more sources

Trend of HIV Transmitted Drug Resistance After the Introduction of Single-Tablet Regimens in Southern Taiwan [PDF]

Infection and Drug Resistance, 2022
Hung-Chin Tsai,1– 5 I-Tzu Chen,1 Hui-Min Chang,6– 8 Susan Shin-Jung Lee,1,2 Yao-Shen Chen1,2 1Division of Infectious Diseases, Department of Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan; 2Faculty of Medicine, School of Medicine ...
Tsai HC, Chen IT, Chang HM, Lee SSJ, Chen YS   +4 more
doaj   +2 more sources

Moderate prevalence of HIV-1 transmitted drug resistance mutations in southern Brazil [PDF]

AIDS Research and Therapy, 2019
Background Despite the advances in therapy, the occurrence of drug-resistant human immunodeficiency virus type 1 (HIV-1) is a major obstacle to successful treatment.
Larissa Danielle Bahls, Pedro Henrique Canezin, Edna Maria Vissoci Reiche, José Carlos Couto Fernandez, José Ricardo Colleti Dias, Vera Alice Fernandes Meneguetti, Luis Toshio Ueda, Dennis Armando Bertolini   +7 more
doaj   +2 more sources

Transmitted drug resistance and transmission clusters among ART-naïve HIV-1-infected individuals from 2019 to 2021 in Nanjing, China. [PDF]

Front Public Health, 2023
Xu Y, Shi H, Dong X, Ding C, Wu S, Li X, Zhang H, Qiao M, Li X, Zhu Z.   +9 more
europepmc   +2 more sources

Primary HIV-1 resistance: Persistence of transmitted drug resistance mutations [PDF]

Archives of Biological Sciences, 2012
Transmitted drug resistance (TDR) is one of the consequences of the high variability of HIV-1. The widespread use of antiretroviral therapy for the treatment of HIV-1 infection results in a large circulating pool of resistant virus variants.
Nikolić Valentina, Salemović D., Jevtović Đ., Pešić-Pavlović I., Zerjav S., Ranin J., Siljić M., Stanojević M.   +7 more
doaj   +1 more source

Future of Antiretroviral Drugs and Evolution of HIV-1 Drug Resistance

Viruses, 2023
Highly active antiretroviral (ARV) therapy has been used for many years, but the use in low- and middle-income countries of antiretroviral drugs with low genetic barrier to resistance, combined with limited availability of viral load testing, has led to ...
Charlotte Charpentier, Quentin Le Hingrat, Valentine Marie Ferré, Florence Damond, Diane Descamps   +4 more
doaj   +1 more source

Minority HIV-1 drug resistance mutations are present in antiretroviral treatment-naïve populations and associate with reduced treatment efficacy. [PDF]

PLoS Medicine, 2008
BACKGROUND: Transmitted HIV-1 drug resistance can compromise initial antiretroviral therapy (ART); therefore, its detection is important for patient management.
Jeffrey A Johnson, Jin-Fen Li, Xierong Wei, Jonathan Lipscomb, David Irlbeck, Charles Craig, Amanda Smith, Diane E Bennett, Michael Monsour, Paul Sandstrom, E Randall Lanier, Walid Heneine   +11 more
doaj   +1 more source