Results 11 to 20 of about 4,157,477 (289)
National prevalence and trends of HIV transmitted drug resistance in Mexico. [PDF]
PLoS ONE, 2011 BACKGROUND: Transmitted drug resistance (TDR) remains an important concern for the management of HIV infection, especially in countries that have recently scaled-up antiretroviral treatment (ART) access.
Santiago Avila-Ríos +10 more
doaj +6 more sources
PLoS ONE, 2010 BackgroundThe aim of this study is to analyse the prevalence of transmitted drug resistance, TDR, and the impact of TDR on treatment success in the German HIV-1 Seroconverter Cohort.MethodsGenotypic resistance analysis was performed in treatment-naïve ...
Barbara Bartmeyer +10 more
doaj +5 more sources
Transmitted drug resistance in patients with acute/recent HIV infection in Brazil
Brazilian Journal of Infectious Diseases, 2017 Introduction: The widespread use of antiretroviral therapy increased the transmission of antiretroviral resistant HIV strains. Antiretroviral therapy initiation during acute/recent HIV infection limits HIV reservoirs and improves immune response in HIV ...
Ana Cristina G. Ferreira +7 more
doaj +5 more sources
Transmitted drug resistance in French HIV-2-infected patients.
AIDS, 2013 International audienceWe report the first transmitted drug resistance survey study in HIV-2-infected patients living in France. The prevalence of transmitted drug resistance was 5.0% (95% confidence interval, 0.1-9.9) with mutations detected only in ...
Matheron, Sophie +11 more
core +4 more sources
Transmitted HIV drug resistance- does the problem exists in Nepal?
Journal of Nepal Medical Association, 2014 Surendra Karki
doaj +6 more sources
Prevalence of HIV Transmitted Drug Resistance in Nanjing from 2018 to 2021. [PDF]
Infect Drug Resist, 2023 Transmitted drug resistance (TDR) is a major challenge in the clinical management of acquired immunodeficiency syndrome (AIDS). Therefore, this study aimed to investigate the epidemic characteristics of and risk factors for human immunodeficiency virus (HIV)-1 TDR in Nanjing from 2018 to 2021 to provide support for clinical management.The HIV-1 Pol ...
Su Y +9 more
europepmc +5 more sources
Community
HIV Medicine, 2014 ObjectivesAs community viral load (CVL) measurements are associated with the incidence of new HIV‐1 infections in a population, we hypothesized that similarly measured community drug resistance (CDR) could predict the prevalence of transmitted drug resistance (TDR).MethodsBetween 2001 and 2011, the prevalences of HIV‐1 drug resistance for patients with
Tilghman, MW +7 more
openaire +4 more sources
HIV, transmitted drug resistance, and the paradox of preexposure prophylaxis [PDF]
Proceedings of the National Academy of Sciences, 2010 The administration of antiretrovirals before HIV exposure to prevent infection (i.e., preexposure prophylaxis; PrEP) is under evaluation in clinical trials. Because PrEP is based on antiretrovirals, there is considerable concern that it could substantially increase transmitted resistance, particularly in resource-rich countries.
Virginie, Supervie +3 more
openaire +2 more sources
Transmitted drug resistance to antiretroviral drugs in Spain during the period 2019–2021
Journal of Medical Virology, 2023 AbstractTo evaluate the prevalence of transmitted drug resistance (TDR) to nucleoside and nonnucleoside reverse transcriptase inhibitors (NRTI, NNRTI), protease inhibitors (PI), and integrase strand transfer inhibitors (INSTI) in Spain during the period 2019–2021, as well as to evaluate transmitted clinically relevant resistance (TCRR) to ...
Laura Viñuela +27 more
openaire +7 more sources
Molecular mechanisms of drug resistance in natural Leishmania populations vary with genetic background [PDF]
, 2012 The evolution of drug-resistance in pathogens is a major global health threat. Elucidating the molecular basis of pathogen drug-resistance has been the focus of many studies but rarely is it known whether a drug-resistance mechanism identified is ...
Sylke Müller +39 more
core +5 more sources