Results 11 to 20 of about 79,702 (253)

High Levels of Transmitted HIV Drug Resistance in a Study in Papua New Guinea. [PDF]

PLoS ONE, 2017
IntroductionPapua New Guinea is a Pacific Island nation of 7.3 million people with an estimated HIV prevalence of 0.8%. ART initiation and monitoring are guided by clinical staging and CD4 cell counts, when available.
Evelyn Lavu, Ellan Kave, Euodia Mosoro, Jessica Markby, Eman Aleksic, Janet Gare, Imogen A Elsum, Gideon Nano, Petronia Kaima, Nick Dala, Anup Gurung, Silvia Bertagnolio, Suzanne M Crowe, Mark Myatt, Anna C Hearps, Michael R Jordan   +15 more
doaj   +2 more sources

Transmitted drug resistance in patients with acute/recent HIV infection in Brazil

Brazilian Journal of Infectious Diseases, 2017
Introduction: The widespread use of antiretroviral therapy increased the transmission of antiretroviral resistant HIV strains. Antiretroviral therapy initiation during acute/recent HIV infection limits HIV reservoirs and improves immune response in HIV ...
Ana Cristina G. Ferreira, Lara E. Coelho, Eduarda Grinsztejn, Carlos S. de Jesus, Monick L. Guimarães, Valdiléa G. Veloso, Beatriz Grinsztejn, Sandra W. Cardoso   +7 more
doaj   +2 more sources

Predicting the risk and speed of drug resistance emerging in soil-transmitted helminths during preventive chemotherapy [PDF]

Nature Communications
Control of soil-transmitted helminths relies heavily on regular large-scale deworming of high-risk groups (e.g., children) with benzimidazole derivatives.
Luc E. Coffeng, Wilma A. Stolk, Sake J. de Vlas   +2 more
doaj   +2 more sources

HIV-1-Transmitted Drug Resistance and Transmission Clusters in Newly Diagnosed Patients in Portugal Between 2014 and 2019. [PDF]

Front Microbiol, 2022
OBJECTIVE: To describe and analyze transmitted drug resistance (TDR) between 2014 and 2019 in newly infected patients with HIV-1 in Portugal and to characterize its transmission networks.
Pingarilho M, Pimentel V, Miranda MNS, Silva AR, Diniz A, Ascenção BB, Piñeiro C, Koch C, Rodrigues C, Caldas C, Morais C, Faria D, da Silva EG, Teófilo E, Monteiro F, Roxo F, Maltez F, Rodrigues F, Gaião G, Ramos H, Costa I, Germano I, Simões J, Oliveira J, Ferreira J, Poças J, da Cunha JS, Soares J, Henriques J, Mansinho K, Pedro L, Aleixo MJ, Gonçalves MJ, Manata MJ, Mouro M, Serrado M, Caixeiro M, Marques N, Costa O, Pacheco P, Proença P, Rodrigues P, Pinho R, Tavares R, de Abreu RC, Côrte-Real R, Serrão R, Castro RSE, Nunes S, Faria T, Baptista T, Martins MRO, Gomes P, Mendão L, Simões D, Abecasis A.   +55 more
europepmc   +2 more sources

The prevalence of HIV-1 drug resistance among antiretroviral treatment naïve individuals in mainland China: a meta-analysis. [PDF]

PLoS ONE, 2014
BACKGROUND: Surveillance of drug resistance in antiretroviral treatment-naïve patients in China is needed to ensure optimal treatment outcomes and control of the human immunodeficiency virus (HIV) epidemic.
Yingying Su, Fujie Zhang, Huixin Liu, M Kumi Smith, Lin Zhu, Jing Wu, Ning Wang   +6 more
doaj   +1 more source

Characterization of Human Immunodeficiency Virus-1 Transmission Clusters and Transmitted Drug-Resistant Mutations in Croatia from 2019 to 2022

Viruses, 2023
Molecular epidemiology of HIV-1 infection is challenging due to the highly diverse HIV-genome. We investigated the genetic diversity and prevalence of transmitted drug resistance (TDR) followed by phylogenetic analysis in 270 HIV-1 infected, treatment ...
Ana Planinić, Josip Begovac, Filip Rokić, Petra Šimičić, Maja Oroz, Katja Jakovac, Oliver Vugrek, Snjezana Zidovec-Lepej   +7 more
doaj   +1 more source

HIV-1 drug-resistance surveillance among treatment-experienced and -naïve patients after the implementation of antiretroviral therapy in Ghana. [PDF]

PLoS ONE, 2013
BACKGROUND: Limited HIV-1 drug-resistance surveillance has been carried out in Ghana since the implementation of antiretroviral therapy (ART). This study sought to provide data on the profile of HIV-1 drug resistance in ART-experienced and newly ...
Nicholas I Nii-Trebi, Shiro Ibe, Jacob S Barnor, Koichi Ishikawa, James A M Brandful, Sampson B Ofori, Shoji Yamaoka, William K Ampofo, Wataru Sugiura   +8 more
doaj   +1 more source

HIV Drug Resistance (HIVDR) in Antiretroviral Therapy-Naïve Patients in Tanzania not Eligible for WHO Threshold HIVDR Survey is Dramatically High. [PDF]

, 2011
The World Health Organization (WHO) has recommended guidelines for a HIV drug resistance (HIVDR) survey for resource-limited countries. Eligibility criteria for patients include age below 25 years in order to focus on the prevalence of transmitted HIVDR (
Majinge, Charles, Mildner Miriam, Hartwig Klinker, Kasang Christa, Stich, August, Jacobs, Graeme Brendon, Graeme B Jacobs, Mildner, Miriam, Kalluvya, Samuel, Hensel, Irina, Gert van Zyl, Kongola Gilbert, Kalluvya Samuel, Hensel Irina, Mlewa, Mathias, Klinker, Hartwig, van Zyl, Gert, Miriam Mildner, van Zyl Gert, Christa Kasang, Mathias Mlewa, Wolfgang Preiser, Stich August, Bodem Jochen, Preiser, Wolfgang, Anne Horn, Klinker Hartwig, Eleni Koutsilieri, Kasang, Christa, Jacobs, Graeme B, Jochen Bodem, Scheller Carsten, Scheller, Carsten, Weissbrich Benedikt, Jacobs, Graeme B., Mlewa Mathias, Jacobs Graeme B., Koutsilieri, Eleni, Preiser Wolfgang, Charles Majinge, Koutsilieri Eleni, Irina Hensel, Rethwilm, Axel, Gilbert Kongola, Axel Rethwilm, Kongola, Gilbert, Horn Anne, Majinge Charles, August Stich, Horn, Anne, Bodem, Jochen, Mllewa, Mathias, Graeme B. Jacobs, Samuel Kalluvya, Carsten Scheller, Rethwilm Axel, Benedikt Weissbrich, Weissbrich, Benedikt   +57 more
core   +1 more source

The emergence of HIV transmitted resistance in Botswana: "when will the WHO detection threshold be exceeded?". [PDF]

PLoS ONE, 2007
The Botswana antiretroviral program began in 2002 and currently treats 42,000 patients, with a goal of treating 85,000 by 2009. The World Health Organization (WHO) has begun to implement a surveillance system for detecting transmitted resistance that ...
Raffaele Vardavas, Sally Blower
doaj   +1 more source

Explaining risk factors for drug-resistant tuberculosis in England and Wales: contribution of primary and secondary drug resistance [PDF]

, 2004
Drug-resistant tuberculosis can be transmitted (primary) or develop during the course of treatment (secondary). We investigated risk factors for each type of resistance.
Glynn, JR, Story, A, Hayward, AC, Watson, JM, Conaty, SJ, Drobniewski, FA   +5 more
core   +1 more source