Results 21 to 30 of about 4,157,477 (289)

Evolutionary pathways of transmitted drug-resistant HIV-1 [PDF]

Journal of Antimicrobial Chemotherapy, 2011
Several large studies in Europe and the USA revealed that approximately 10% of all newly diagnosed patients harbour HIV-1 variants with at least one major resistance-associated mutation. In this review we discuss the underlying mechanisms that drive the evolution of drug-resistant viruses after transmission to the new host.
Pingen, Marieke, Nijhuis, M, Bruijn, Jan, Boucher, Charles, Wensing, AMJ   +4 more
openaire   +2 more sources

Drug resistance in the sexually transmitted protozoan Trichomonas vaginalis [PDF]

Cell Research, 2003
Trichomoniasis is the most common, sexually transmitted infection. It is caused by the flagellated protozoan parasite Trichomonas vaginalis. Symptoms include vaginitis and infections have been associated with preterm delivery, low birth weight and increased infant mortality, as well as predisposing to HIV/AIDS and cervical cancer.
Dunne, R. L., Dunn, L. A., Upcroft, P., O'Donoghue, P. J., Upcroft, J. A.   +4 more
openaire   +5 more sources

Characterization of Human Immunodeficiency Virus-1 Transmission Clusters and Transmitted Drug-Resistant Mutations in Croatia from 2019 to 2022

Viruses, 2023
Molecular epidemiology of HIV-1 infection is challenging due to the highly diverse HIV-genome. We investigated the genetic diversity and prevalence of transmitted drug resistance (TDR) followed by phylogenetic analysis in 270 HIV-1 infected, treatment ...
Ana Planinić, Josip Begovac, Filip Rokić, Petra Šimičić, Maja Oroz, Katja Jakovac, Oliver Vugrek, Snjezana Zidovec-Lepej   +7 more
doaj   +1 more source

HIV-1 drug-resistance surveillance among treatment-experienced and -naïve patients after the implementation of antiretroviral therapy in Ghana. [PDF]

PLoS ONE, 2013
BACKGROUND: Limited HIV-1 drug-resistance surveillance has been carried out in Ghana since the implementation of antiretroviral therapy (ART). This study sought to provide data on the profile of HIV-1 drug resistance in ART-experienced and newly ...
Nicholas I Nii-Trebi, Shiro Ibe, Jacob S Barnor, Koichi Ishikawa, James A M Brandful, Sampson B Ofori, Shoji Yamaoka, William K Ampofo, Wataru Sugiura   +8 more
doaj   +1 more source

High Levels of Transmitted HIV Drug Resistance in a Study in Papua New Guinea.

PLoS ONE, 2017
IntroductionPapua New Guinea is a Pacific Island nation of 7.3 million people with an estimated HIV prevalence of 0.8%. ART initiation and monitoring are guided by clinical staging and CD4 cell counts, when available.
Evelyn Lavu, Ellan Kave, Euodia Mosoro, Jessica Markby, Eman Aleksic, Janet Gare, Imogen A Elsum, Gideon Nano, Petronia Kaima, Nick Dala, Anup Gurung, Silvia Bertagnolio, Suzanne M Crowe, Mark Myatt, Anna C Hearps, Michael R Jordan   +15 more
doaj   +1 more source

HIV Drug Resistance (HIVDR) in Antiretroviral Therapy-Naïve Patients in Tanzania not Eligible for WHO Threshold HIVDR Survey is Dramatically High. [PDF]

, 2011
The World Health Organization (WHO) has recommended guidelines for a HIV drug resistance (HIVDR) survey for resource-limited countries. Eligibility criteria for patients include age below 25 years in order to focus on the prevalence of transmitted HIVDR (
Majinge, Charles, Mildner Miriam, Hartwig Klinker, Kasang Christa, Stich, August, Jacobs, Graeme Brendon, Graeme B Jacobs, Mildner, Miriam, Kalluvya, Samuel, Hensel, Irina, Gert van Zyl, Kongola Gilbert, Kalluvya Samuel, Hensel Irina, Mlewa, Mathias, Klinker, Hartwig, van Zyl, Gert, Miriam Mildner, van Zyl Gert, Christa Kasang, Mathias Mlewa, Wolfgang Preiser, Stich August, Bodem Jochen, Preiser, Wolfgang, Anne Horn, Klinker Hartwig, Eleni Koutsilieri, Kasang, Christa, Jacobs, Graeme B, Jochen Bodem, Scheller Carsten, Scheller, Carsten, Weissbrich Benedikt, Jacobs, Graeme B., Mlewa Mathias, Jacobs Graeme B., Koutsilieri, Eleni, Preiser Wolfgang, Charles Majinge, Koutsilieri Eleni, Irina Hensel, Rethwilm, Axel, Gilbert Kongola, Axel Rethwilm, Kongola, Gilbert, Horn Anne, Majinge Charles, August Stich, Horn, Anne, Bodem, Jochen, Mllewa, Mathias, Graeme B. Jacobs, Samuel Kalluvya, Carsten Scheller, Rethwilm Axel, Benedikt Weissbrich, Weissbrich, Benedikt   +57 more
core   +2 more sources

The emergence of HIV transmitted resistance in Botswana: "when will the WHO detection threshold be exceeded?". [PDF]

PLoS ONE, 2007
The Botswana antiretroviral program began in 2002 and currently treats 42,000 patients, with a goal of treating 85,000 by 2009. The World Health Organization (WHO) has begun to implement a surveillance system for detecting transmitted resistance that ...
Raffaele Vardavas, Sally Blower
doaj   +1 more source

Novel insights in the fecal egg count reduction test for monitoring drug efficacy against soil-transmitted helminths in large-scale treatment programs [PDF]

, 2011
Background The fecal egg count reduction test (FECRT) is recommended to monitor drug efficacy against soil-transmitted helminths (STHs) in public health.
Robert J. Dobson, Charlier, Johannes, Jozef Vercruysse, Speybroeck, Niko, Levecke Bruno, Charlier Johannes, Dobson, Robert J, Dobson, R.J., Charlier, J., Vercruysse, J., Johannes Charlier, Vercruysse Jozef, Bruno Levecke, Niko Speybroeck, Speybroeck, N., Vercruysse, Jozef, Levecke, B., Dobson Robert J., Levecke, Bruno, Robert J Dobson, Speybroeck Niko   +20 more
core   +1 more source

HIV Transmitted Drug Resistance in the Philippines: The Case for Baseline Genotyping and Drug Resistance Testing [PDF]

Open Forum Infectious Diseases, 2017
Abstract Background The Philippines has one of the fastest growing HIV epidemics in the world. Parallel to the increase is a shift in HIV subtype from B to CRF01_AE. No transmitted drug resistance (TDR) surveillance has ever been conducted.
Edsel Maurice Salvana, Brian Schwem, Christine Penalosa, Geraldine Arevalo, Nina Dungca, Jodor Lim, Katerina Leyritana, Raul Destura   +7 more
openaire   +1 more source

Soil-transmitted helminth reinfection after drug treatment : a systematic review and meta-analysis [PDF]

, 2012
BACKGROUND: Soil-transmitted helminth (STH) infections (i.e., Ascaris lumbricoides, hookworm, and Trichuris trichiura) affect more than a billion people. Preventive chemotherapy (i.e., repeated administration of anthelmintic drugs to at-risk populations),
Charles H. King (78462), Xiao-Nong Zhou (92570), King Charles H., Sara Melville (165920), King, C. H., Jia, T. W., Utzinger, J., Jürg Utzinger (39609), Zhou Xiao-Nong, Jia Tie-Wu, Sara Melville, Zhou, X. N., Charles H King, Utzinger Jürg, Tie-Wu Jia, Melville, S., Melville Sara, Xiao-Nong Zhou, Jürg Utzinger, Tie-Wu Jia (165917)   +19 more
core   +1 more source