Results 21 to 30 of about 76,872 (109)

An analysis of drug resistance among people living with HIV/AIDS in Shanghai, China.

PLoS ONE, 2017
BackgroundUnderstanding the mechanisms of drug resistance can facilitate better management of antiretroviral therapy, helping to prevent transmission and decrease the morbidity and mortality of people living with HIV/AIDS.
Fengdi Zhang, Li Liu, Meiyan Sun, Jianjun Sun, Hongzhou Lu   +4 more
doaj   +1 more source

Transmission and prevalence of drug-resistant tuberculosis in a Brazilian setting under a directly observed therapy short-course strategy

Revista da Sociedade Brasileira de Medicina Tropical, 2020
INTRODUCTION: We aimed to estimate the prevalence and transmission of drug-resistant tuberculosis in a high-burden Brazilian setting under directly observed therapy short-course strategy.
Fábio Oliveira Latrilha, Vera Simonsen, Juliana Maira Watanabe Pinhata, Angela Pires Brandão, Vera Maria Neder Galesi, Eliseu Alves Waldman, Lucilaine Ferrazoli   +6 more
doaj   +1 more source

Acquired and Transmitted Multidrug Resistant Tuberculosis: The Role of Social Determinants. [PDF]

PLoS ONE, 2016
Although risk factors for multi-drug resistant tuberculosis are known, few studies have differentiated between acquired and transmitted resistance.
Anna Odone, Roger Calderon, Mercedes C Becerra, Zibiao Zhang, Carmen C Contreras, Rosa Yataco, Jerome Galea, Leonid Lecca, Matthew H Bonds, Carole D Mitnick, Megan B Murray   +10 more
doaj   +1 more source

High viremia and low level of transmitted drug resistance in anti-retroviral therapy-naïve perinatally-infected children and adolescents with HIV-1 subtype C infection

BMC Infectious Diseases, 2012
Background High plasma viremia in HIV-1 infection is associated with rapid CD4 cell decline and faster disease progression. Children with HIV infection have high viral loads, particularly in early childhood.
Neogi Ujjwal, Sahoo Pravat Nalini, De Costa Ayesha, Shet Anita   +3 more
doaj   +1 more source

Prevalence and trends in transmitted and acquired antiretroviral drug resistance, Washington, DC, 1999–2014

BMC Research Notes, 2017
Background Drug resistance limits options for antiretroviral therapy (ART) and results in poorer health outcomes among HIV-infected persons. We sought to characterize resistance patterns and to identify predictors of resistance in Washington, DC. Methods
Annette M. Aldous, Amanda D. Castel, David M. Parenti, the DC Cohort Executive Committee   +3 more
doaj   +1 more source

Epidemic Characteristics of HIV Drug Resistance in Hefei, Anhui Province

Pathogens, 2022
To study the characteristics of HIV pretreatment drug resistance (PDR) and acquired drug resistance (ADR) in Hefei, a cross-sectional survey was used to collect 816 samples from newly reported HIV infections from 2017 to 2020 and 127 samples from HIV ...
Shan Zheng, Jianjun Wu, Jingjing Hao, Dong Wang, Zhongwang Hu, Lei Liu, Chang Song, Jing Hu, Yanhua Lei, Hai Wang, Lingjie Liao, Yi Feng, Yiming Shao, Yuhua Ruan, Hui Xing   +14 more
doaj   +1 more source

National prevalence and trends of HIV transmitted drug resistance in Mexico. [PDF]

PLoS ONE, 2011
BACKGROUND: Transmitted drug resistance (TDR) remains an important concern for the management of HIV infection, especially in countries that have recently scaled-up antiretroviral treatment (ART) access.
Santiago Avila-Ríos, Claudia García-Morales, Daniela Garrido-Rodríguez, Christopher E Ormsby, Ramón Hernández-Juan, Jaime Andrade-Villanueva, Luz A González-Hernández, Indiana Torres-Escobar, Samuel Navarro-Álvarez, Gustavo Reyes-Terán, Mexican HIV Molecular Epidemiology Project Group   +10 more
doaj   +1 more source

Prevalence of transmitted drug resistance and impact of transmitted resistance on treatment success in the German HIV-1 Seroconverter Cohort.

PLoS ONE, 2010
BackgroundThe aim of this study is to analyse the prevalence of transmitted drug resistance, TDR, and the impact of TDR on treatment success in the German HIV-1 Seroconverter Cohort.MethodsGenotypic resistance analysis was performed in treatment-naïve ...
Barbara Bartmeyer, Claudia Kuecherer, Claudia Houareau, Johanna Werning, Kathrin Keeren, Sybille Somogyi, Christian Kollan, Heiko Jessen, Stephan Dupke, Osamah Hamouda, German HIV-1 Seroconverter Study Group   +10 more
doaj   +1 more source

Predicting the risk and speed of drug resistance emerging in soil-transmitted helminths during preventive chemotherapy

Nature Communications
Control of soil-transmitted helminths relies heavily on regular large-scale deworming of high-risk groups (e.g., children) with benzimidazole derivatives.
Luc E. Coffeng, Wilma A. Stolk, Sake J. de Vlas   +2 more
doaj   +1 more source

Cellular HIV-1 DNA levels in drug sensitive strains are equivalent to those in drug resistant strains in newly-diagnosed patients in Europe. [PDF]

PLoS ONE, 2010
HIV-1 genotypic drug resistance is an important threat to the success of antiretroviral therapy and transmitted resistance has reached 9% prevalence in Europe.
Victoria L Demetriou, David A M C van de Vijver, Ioanna Kousiappa, Claudia Balotta, Bonaventura Clotet, Zehava Grossman, Louise B Jørgensen, Snjezana Z Lepej, Itzchak Levy, Claus Nielsen, Dimitrios Paraskevis, Mario Poljak, Francois Roman, Lidia Ruiz, Jean-Claude Schmidt, Anne-Mieke Vandamme, Anne-Mieke Vandamme, Kristel Van Laethem, Jurgen Vercauteren, Leondios G Kostrikis   +19 more
doaj   +1 more source