Results 41 to 50 of about 76,872 (109)

Prevalence and persistence of transmitted drug resistance mutations in the German HIV-1 Seroconverter Study Cohort.

PLoS ONE, 2019
The prevalence of transmitted drug resistance (TDR) in antiretroviral therapy (ART)-naïve individuals remains stable in most developed countries despite a decrease in the prevalence of acquired drug resistance.
Patrycja Machnowska, Karolin Meixenberger, Daniel Schmidt, Heiko Jessen, Heribert Hillenbrand, Barbara Gunsenheimer-Bartmeyer, Osamah Hamouda, Claudia Kücherer, Norbert Bannert, German HIV-1 Seroconverter Study Group   +9 more
doaj   +1 more source

Drug-Resistant Tuberculosis Transmission and Resistance Amplification within Families

Emerging Infectious Diseases, 2012
Drug-resistant tuberculosis is caused by transmission of resistant strains of Mycobacterium tuberculosis and by acquisition of resistance through inadequate treatment. We investigated the clinical and molecular features of the disease in 2 families after
James A. Seddon, Rob M. Warren, Donald A. Enarson, Nulda Beyers, H. Simon Schaaf   +4 more
doaj   +1 more source

Frequency of Major Transmitted Integrase Resistance in Poland Remains Low Despite Change in Subtype Variability

Viruses
With the widespread use of integrase inhibitors and the expanding use of long-acting cabotegravir in both pre-exposure prophylaxis and antiretroviral treatment, molecular surveillance on the transmission of integrase resistance has regained clinical ...
Kaja Mielczak, Karol Serwin, Anna Urbańska, Bogusz Aksak-Wąs, Malwina Karasińska-Cieślak, Elżbieta Mularska, Adam Witor, Paweł Jakubowski, Maria Hlebowicz, Monika Bociąga-Jasik, Elżbieta Jabłonowska, Aleksandra Szymczak, Bartosz Szetela, Władysław Łojewski, Miłosz Parczewski   +14 more
doaj   +1 more source

How Much Do We Know about Drug Resistance Due to PrEP Use? Analysis of Experts' Opinion and Its Influence on the Projected Public Health Impact.

PLoS ONE, 2016
BackgroundRandomized controlled trials reported that pre-exposure prophylaxis (PrEP) with tenofovir and emtricitabine rarely selects for drug resistance. However, drug resistance due to PrEP is not completely understood.
Dobromir T Dimitrov, Marie-Claude Boily, Timothy B Hallett, Jan Albert, Charles Boucher, John W Mellors, Deenan Pillay, David A M C van de Vijver   +7 more
doaj   +1 more source

HIV-1 drug resistance and genetic transmission networks among patients with sexually transmitted HIV in Ningxia, China

Frontiers in Public Health
BackgroundOver the past decade, sexual transmission has become a dominant source of new HIV-1 infection in China. However, very few studies have been conducted to characterize the two sexual transmissions, homosexual and heterosexual transmission.
Jianxin Pei, Zhonglan Wu, Zhonglan Wu, Bingqian Si, Chunhua Ma, Yichang Liu, Xiaofa Ma, Wenhe Kuai, Yinhao Zhang, Yong Li   +9 more
doaj   +1 more source

HIV-1 genetic diversity and resistance to antiretroviral drugs among pregnant women in Ribeirão Preto (SP), Brazil. Cross-sectional study

São Paulo Medical Journal
BACKGROUND: Increasing genetic diversity of HIV-1 and emergence of drug-resistant mutations may reduce the efficacy of antiretroviral therapy and prophylaxis that are used to prevent mother-to-child transmission.
Ana Teresa Mancini Pimenta, Isadora Alonso Correa, Patricia Pereira dos Santos Melli, Renata Abduch, Geraldo Duarte, José Carlos Couto-Fernandez, Silvana Maria Quintana   +6 more
doaj   +1 more source

Transmitted and Acquired HIV-1 Drug Resistance from a Family: A Case Study

Infection and Drug Resistance, 2020
Liting Yan,1,2,* Fengting Yu,1,2,* Huimin Zhang,1,3 Hongxin Zhao,1,2 Linghang Wang,1,2 Zaiyan Liang,1,2 Xia Zhang,1,2 Liang Wu,1,2 Hongyuan Liang,1,2 Siyuan Yang,1,2 Yunxia Tang,1,2 Fujie Zhang1,2 1Beijing Ditan Hospital, Capital Medical University ...
Yan L, Yu F, Zhang H, Zhao H, Wang L, Liang Z, Zhang X, Wu L, Liang H, Yang S, Tang Y, Zhang F   +11 more
doaj  

Contemporary Challenges in Sexually Transmitted Diseases: From Diagnostics to Drug Resistance

Venereology
Sexually transmitted diseases (STDs) continue to represent a substantial burden on public health and society worldwide. With significant implications for social, economic, and public health, STDsare a major global health concern.
Anjali Pandit, Sandeep K. Shrivastava, Sonia Sethi   +2 more
doaj   +1 more source

Transmitted drug resistance and subtype patterns of viruses from reported new HIV diagnoses in Germany, 2017-2020. [PDF]

BMC Infect Dis, 2023
Fiebig U, Altmann B, Hauser A, Koppe U, Hanke K, Gunsenheimer-Bartmeyer B, Bremer V, Baumgarten A, Bannert N.   +8 more
europepmc   +1 more source

Transmitted Drug Resistance Against Integrase Strand Transfer Inhibitors in Iranian HIV-Infected Naïve Patients. [PDF]

Avicenna J Med Biotechnol, 2023
Hashempour A, Musavi Z, Moayedi J, Hasanshahi Z, Dehghani B, Ghasabi F, Joulaei H.   +6 more
europepmc   +1 more source