Results 1 to 10 of about 1,475 (161)

Noninvasive quantification of granzyme B in cardiac allograft rejection using targeted ultrasound imaging [PDF]

Frontiers in Immunology, 2023
ObjectiveEndomyocardial biopsy is the gold standard method for the diagnosis of cardiac allograft rejection. However, it causes damage to the heart.
Yunjie Jin, Yunjie Jin, Peng Gao, Lifei Liang, Lifei Liang, Yuhang Wang, Jiawei Li, Jiawei Li, Jiyan Wang, Jiyan Wang, Jiangang Hou, Cheng Yang, Cheng Yang, Cheng Yang, Xiaolin Wang   +14 more
doaj   +5 more sources

Transplantation of Bone Marrow-Derived Mesenchymal Stem Cells Promotes Delayed Wound Healing in Diabetic Rats [PDF]

Journal of Diabetes Research, 2013
In this paper, we established a delayed wound healing model on diabetic rat to mimic the pathophysiology of clinical patients who suffered from diabetic foot ulcers.
Jiangbo Wan, Liulu Xia, Wenjia Liang, Yi Liu, Qian Cai   +4 more
doaj   +4 more sources

Nanotherapeutics in transplantation: How do we get to clinical implementation? [PDF]

American Journal of Transplantation, Volume 22, Issue 5, Page 1293-1298, May 2022., 2022
Patients undergoing organ transplantation transition from one life‐altering issue (organ dysfunction) to a lifelong commitment—immunosuppression. Regimens of immunosuppressive agents (ISAs) come with significant side effects and comorbidities. Recently, the use of nanoparticles (NPs) as a solution to the problems associated with the long‐term and ...
Leah Plumblee, Carl Atkinson, Dinesh Jaishankar, Evan Scott, Gregory T. Tietjen, Satish N. Nadig   +5 more
wiley   +2 more sources

Immunosuppressive protocols with tacrolimus after cryopreserved aortal allotransplantation in rats. [PDF]

PLoS ONE, 2018
OBJECTIVES AND DESIGN:The aim of our study was to simulate in rats all aspects and techniques used in our new clinical program of cryopreserved alloarterial transplantation and investigate the influence of two immunosuppressive protocols with tacrolimus ...
Rudolf Spunda, Jan Hruby, Pavel Mericka, Mikulas Mlcek, Ondrej Pecha, Kathrin Splith, Moritz Schmelzle, Felix Krenzien, Jaroslav Lindner, Ivan Matia, Miroslav Spacek   +10 more
doaj   +2 more sources

Two Compartment Evaluation of Liver Grafts During Acellular Room Temperature Machine Perfusion (acRTMP) in a Rat Liver Transplant Model [PDF]

Frontiers in Medicine, 2022
BackgroundSubnormothermic machine perfusion (SNMP) of liver grafts is currently less clinically developed than normothermic and hypothermic approaches, but may have logistical advantages.
Nader Abraham, Min Zhang, Paul Cray, Qimeng Gao, Kannan P. Samy, Ryan Neill, Greta Cywinska, JonCarlo Migaly, Riley Kahan, Arya Pontula, Samantha E. Halpern, Caroline Rush, Jude Penaflor, Samuel J. Kesseli, Madison Krischak, Mingqing Song, Matthew G. Hartwig, Justin J. Pollara, Andrew S. Barbas   +18 more
doaj   +2 more sources

Adaptive Immunity and Pathogenesis of Diabetes: Insights Provided by the α4–Integrin Deficient NOD Mouse [PDF]

Cells, 2020
Background: The spontaneously diabetic “non-obese diabetic” (NOD) mouse is a faithful model of human type-1 diabetes (T1D). Methods: Given the pivotal role of α4 integrin (CD49d) in other autoimmune diseases, we generated NOD mice with α4-deficient ...
Salim Oulghazi, Sarah K. Wegner, Gabriele Spohn, Nina Müller, Sabine Harenkamp, Albrecht Stenzinger, Thalia Papayannopoulou, Halvard Bonig   +7 more
doaj   +2 more sources

DIEP Flap Transplantation in Monozygotic Twins for Breast Reconstruction: A Case Report and Literature Review

Journal of Reconstructive Microsurgery Open, 2023
Background Composite tissue allotransplants are performed for various defects when local, or distant reconstructive options are limited. Though this type of transplant replaces similar tissue, it is complicated by immunosuppression.
Cemile Nurdan Ozturk, Arvind D. Manisundaram, Mariangela Rivera, Can Ozturk, Wong Moon   +4 more
doaj   +1 more source

Whole‐Genome Sequencing Revealed a Late‐Maturing Isogenic Rice Koshihikari Integrated with Hd16 Gene Derived from an Ise Shrine Mutant

International Journal of Genomics, Volume 2022, Issue 1, 2022., 2022
We identified the key genes controlling the late maturation of the Japonica cultivar Isehikari, which was found at Ise Jingu Shrine and matures 6 days later than Koshihikari. We conducted a genetics‐based approach through this study. First, the latest mature plants, which flowered later than Isehikari, were segregated in the F2 and F3 generations of ...
Motonori Tomita, Ryotaro Tokuyama, Shosuke Matsumoto, Kazuo Ishii, Vijay Gahlaut   +4 more
wiley   +1 more source

A Comprehensive Update of Cerebral Organoids between Applications and Challenges

Oxidative Medicine and Cellular Longevity, Volume 2022, Issue 1, 2022., 2022
The basic technology of stem cells has been developed and created organoids, which have established a strong interest in regenerative medicine. Different cell types have been used to generate cerebral organoids, which include interneurons and oligodendrocytes (OLs). OLs are fundamental for brain development.
Xiaodong Li, Abdullah Shopit, Jingmin Wang, Sandra Moreno   +3 more
wiley   +1 more source

Role of Hyperglycemia in Isogeneic Islet Transplantation: An Experimental Animal Study [PDF]

Experimental and Clinical Endocrinology & Diabetes, 2008
Study the role of hyperglycemia-induced beta cell loss on grafted islet destruction.Male inbred rats were made diabetic by streptozotocin administration and used as islet donors and/or isograft recipients to probe directly the role of hyperglycemia as an important determinant of transplanted islet fate, following exclusion of immune-related causes of ...
I, Nomikos, K, Kalogerakos, E, Athanasiou, E, Plakokefalos, E, Plakokefales, D, Sioutopoulou, M, Satra, N C, Vamvakopoulos   +7 more
openaire   +2 more sources