Impairment of early fracture healing by skeletal muscle trauma is restored by FK506 [PDF]
BACKGROUND: Heightened local inflammation due to muscle trauma or disease is associated with impaired bone regeneration. METHODS: We hypothesized that FK506, an FDA approved immunomodulatory compound with neurotrophic and osteogenic effects, will ...
Corona, Benjamin T. +8 more
core +2 more sources
Quantitative Changes of Lymph‐ and Hemangiogenesis after Isogenic Heart Transplantation in Rat
Angiogenesis plays important role after solid organ transplantation. Priorly, we found correlation of lymphangiogenesis to organ rejection after heart and lung transplantation in humans. The purpose of the study was to investigate the changes of lymphatics and capillaries after heart transplantation (HTX) in ...
Alexey Dashkevich +5 more
openaire +1 more source
Abstract Book: 25th Congress of the European Hematology Association Virtual Edition, 2020
HemaSphere, Volume 4, Issue S1, Page 1-1168, June 2020.
wiley +1 more source
Macrophage migration inhibitory factor downregulation: a novel mechanism of resistance to anti-angiogenic therapy. [PDF]
Anti-angiogenic therapies for cancer such as VEGF neutralizing antibody bevacizumab have limited durability. While mechanisms of resistance remain undefined, it is likely that acquired resistance to anti-angiogenic therapy will involve alterations of the
Aghi, MK +14 more
core +1 more source
New Methods in Tissue Engineering: Improved Models for Viral Infection [PDF]
New insights in the study of virus and host biology in the context of viral infection are made possible by the development of model systems that faithfully recapitulate the in vivo viral life cycle.
Bhatia, Sangeeta N +4 more
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sCR1sLeX reduces lung allograft ischemia-reperfusion injury but does not ameliorate acute rejection [PDF]
Background: Combined inhibition of complement and leukocyte adhesion by sCR1sLeX reduces lung allograft dysfunction up to 24 h. In the present study its effect on graft function and acute rejection was evaluated up to 5 days after experimental ...
Hamacher, Jürg +3 more
core
Longtransplantatie bij de rat [PDF]
Op grond van de resultaten van het hierboven beschreven onderzoek en de eraan gewijde beschouwingen zijn de volgende conclasies getrokken: 1. Orthotope linkszijdige longtransplantatie bij de rat is operatietechnisch mogelijk. 2.
Marck, Klaas Willem
core +4 more sources
The present study investigated the effects of matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) in transplantation-associated arteriosclerosis by observing their expression in transplanted aortas in rats. Allogenic and isogenic abdominal aortic transplantations were performed and grafts were removed from the recipients
Si-Dong, Wei +5 more
openaire +3 more sources
Combined activities of JNK1 and JNK2 in hepatocytes protect against toxic liver injury [PDF]
Background & Aims: c-Jun N-terminal kinase (JNK)1 and JNK2 are expressed in hepatocytes and have overlapping and distinct functions. JNK proteins are activated, via phosphorylation, in response to acetaminophen- or CCl4-induced liver damage; the level of
Al Masaoudi, Malika +16 more
core +1 more source
Self-Nonself Recognition in the Colonial Protochordate Botryllus schlosseri from Mutsu Bay, Japan [PDF]
Wild Botryllus schlosseri collected from a 5 × 5 m area in Mutsu Bay (Aomori Prefecture, Japan) were tested for alloresponses in intrapopulation colony allorecognition assays (CAAs).
RINKEVICH BARUCH +2 more
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