Results 21 to 30 of about 180,557 (345)
A major function of the immune response is the discrimination of self from nonself. It is this response that must be overcome in transplant rejection. Progress in understanding these basic immune mechanisms has helped to improve clinical outcome and lays the foundation for a new generation of therapies.
A M, Krensky, C, Clayberger
openaire +2 more sources
The unfinished legacy of liver transplantation: Emphasis on immunology [PDF]
Liver transplantation radically changed the philosophy of hepatology practice, enriched multiple areas of basic science, and had pervasive ripple effects in law, public policy, ethics, and theology.
Bachmann +153 more
core +1 more source
Experimental models of organ transplantation played a crucial role to establish the principles of transplantation immunology. The renal transplantation in rodents became the most used model to study the mechanisms of allograft rejection.
Paulo Ney Aguiar Martins +1 more
doaj +1 more source
The changing immunology of organ transplantation [PDF]
The engrafted organ becomes a chimera as the recipient's leukocytes station themselves in the transplant. Remarkably, the recipient becomes chimeric as well, in a reverse migration involving immune cells from the graft.
Demetris AJ +10 more
core +1 more source
Primary graft dysfunction (PGD) is the leading cause of postoperative mortality in lung transplant recipients and the most important risk factor for development of chronic lung allograft dysfunction.
Melissa Querrey +11 more
doaj +1 more source
Solid organ transplantation is the preferred treatment for end-stage organ failure. Although transplant recipients take life-long immunosuppressive drugs, a substantial percentage of them still reject their allografts.
Isabella Pirozzolo +11 more
doaj +1 more source
NK and CD8+ T cell phenotypes predict onset and control of CMV viremia after kidney transplant
CMV causes mostly asymptomatic but lifelong infection. Primary infection or reactivation in immunocompromised individuals can be life-threatening. CMV viremia often occurs in solid organ transplant recipients and associates with decreased graft survival ...
Harry Pickering +17 more
doaj +1 more source
Clonal expansion shapes the human V\u3b41T cell receptor repertoire. [PDF]
Cellular and Molecular Immunology aims to report the dynamic progress being made in China and abroad in immunological research, and welcomes high-quality Research Articles, Reviews and Brief Reports across a broad range of topics including, but not ...
Dieli, F., Meraviglia, S.
core +1 more source
ACTH treatment promotes murine cardiac allograft acceptance
Heart transplantation is the optimal therapy for patients with end-stage heart disease, but its long-term outcome remains inadequate. Recent studies have highlighted the importance of the melanocortin receptors (MCRs) in inflammation, but how MCRs ...
Jing Zhao +13 more
doaj +1 more source
Chimerism after organ transplantation [PDF]
Recent evidence suggests that passenger leukocytes migrate after organ transplantation and produce persistent chimerism, which is essential for sustained survival of the allograft.
Demetris, AJ +6 more
core +1 more source

