Results 21 to 30 of about 99,491 (262)

Pharmacokinetic/pharmacodynamic modelling approaches in paediatric infectious diseases and immunology [PDF]

, 2014
Pharmacokinetic/pharmacodynamic (PKPD) modelling is used to describe and quantify dose-concentration-effect relationships. Within paediatric studies in infectious diseases and immunology these methods are often applied to developing guidance on ...
Hoare, RL, Germovsek, Eva, Standing, JF, Standing, Joseph F., Lewis, J, Barker, Charlotte I.S., Lewis, Joanna, Lestner, Jodi M., Hoare, Rollo L., Barker, CI, Germovsek, E, Lestner, JM   +11 more
core   +1 more source

Patterning the geographies of organ transplantation: corporeality, generosity and justice [PDF]

, 2006
Organ transplantation is now an established treatment for patients with end-stage organ failure, yet there are spatial inequalities in access to this procedure.
Gail Davies, Davies, G, Davies, Gail
core   +1 more source

Mechanisms of calcineurin inhibitor nephrotoxicity in chronic allograft injury [PDF]

, 2012
The first successful transplantation of a human kidney was performed more than 50 years ago by Murray and colleagues in 1954 between identical twins. The success of this transplantation was due to the fact that no significant rejection occurs between ...
Ryan, Michael P., Johnston, Olwyn, Hilary Cassidy, Michael P. Ryan, Slattery, Craig, Tara McMorrow, Cassidy, Hilary, Craig Slattery, Olwyn Johnston, Michael P., McMorrow, Tara   +10 more
core   +2 more sources

Helminths and immunological tolerance [PDF]

, 2014
Current immunosuppression regimens for solid-organ transplantation have shown disappointing efficacy in the prevention of chronic allograft rejection and carry unacceptable risks including toxicity, neoplasia, and life-threatening infection.
McSorley, Henry J., Maizels, Rick M., Maizels, Rick M, Johnston, Chris J C, Wigmore, Stephen J, Johnston, Chris J.C., Wigmore, Stephen J., Anderton, Stephen M, McSorley, Henry J, Anderton, Stephen M., Johnston, Chris J. C., McSorley, Henry J.; id_orcid   +11 more
core   +1 more source

Proceedings of the 25th Annual Congress of the International Liver Transplantation Society [PDF]

, 2020
The 25th Annual Congress of the International Liver Transplantation Society was held in Toronto, Canada, from May 15 to 18, 2019. Surgeons, hepatologists, anesthesiologists, critical care intensivists, radiologists, pathologists, and research scientists ...
Tanaka, T, Hessheimer, A, Kabacam, G, Goldaracena, N, De Martin, E, Vinaixa, C, Victor, D, Kirchner, V, Spiro, M, Yoon, YI, Bhangui, P, Kalisvaart, M, Sapisochin, G, Rammohan, A, Chadha, R, Campos Varela, I, Chan, A, Scalera, I   +17 more
core   +1 more source

The unfinished legacy of liver transplantation: Emphasis on immunology [PDF]

, 2006
Liver transplantation radically changed the philosophy of hepatology practice, enriched multiple areas of basic science, and had pervasive ripple effects in law, public policy, ethics, and theology.
Fadi G. Lakkis, Starzl, TE, Lakkis, FG, Thomas E. Starzl   +3 more
core   +1 more source

Immunology of skin transplantation

Clinics in Dermatology, 2005
Untreated viable allogeneic skin is highly immunogenic. Epidermal Langerhans migrate after transplantation out of the donor skin into the lymph node of the recipient where they can activate T cells capable to mediate rejection. Allogeneic skin is used as a temporary coverage of burn wounds, often in combination with autologous skin grafts.
Richters, C.D., Hoekstra, M.J., du Pont, J.S., Kreis, RW, Kamperdijk, E.W.   +4 more
openaire   +4 more sources

Association Between Dinutuximab Beta Exposure and Post‐End‐of‐Treatment Survival in Neuroblastoma: A Weighted Patient‐Level Analysis of Three Clinical Studies

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko, Holger N. Lode, Alberto Garaventa, Carla Manzitti, Roberto Luksch, Dominique Valteau‐Couanet, Marion Gambart, John Anderson, Juliet Gray, Adela Canete, Lucas Moreno, Aleksandra Wieczorek, Cormac Owens, Shifra Ash, Isaac Yaniv, Genevieve Laureys, Hans Loibner, Katarzyna Śladowska, Ruth Ladenstein, Paweł Kawalec   +19 more
wiley   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Updated international consensus guidelines on the management of cytomegalovirus in solid-organ transplantation. [PDF]

, 2013
Cytomegalovirus (CMV) continues to be one of the most common infections after solid-organ transplantation, resulting in significant morbidity, graft loss, and adverse outcomes.
Gordon, C, Nell Lurain Pediatrics: Lara Danziger Isakov, Humar, A., Zamora, M, Anders Åsberg, Nina Singh, Michaels, M., Reischig, T, Khanna, R, Harrison, J, Kumar, Deepali, Marian Michaels, David R. Snydman, Emily Blumberg, Sunwen Chou, Singh, N, BALDANTI, FAUSTO, Rajiv Khanna, Asberg, Anders, Tomas Reischig, Sester, M, Asberg A, Martin Zamora Treatment: Anders Asberg, Patricia Munoz, MichaelGreen, Rawlinson, W, Lurain, N, Asberg, A., Chou, S., Daniele Lilleri, Kotton, C.N., Danziger-Isakov, Lara, Nassim Kamar, Kotton, CN, Julian Torre Cisneros, B.e.t.s.y.C. Herold, Munoz, P, Vincent Emery, Lilleri, D, Chou, S, Snydman, DR, Graham Paget, Merville, P, Herold, BC, Humar A, Camargo, LF, Allen, U, Huprikar, S, Asberg, A, ABATE, DAVIDE ANTONIO, ChadGordon, ShirishHuprikar, Kumar, D, William Rawlinson Resistance: Sunwen Chou, Caliendo, Angela M, Green, M, Angela M. Caliendo, Humar, A, Manuel, O, Upton Allen, Danziger Isakov, L, Deepali Kumar, Kotton CN, Humar, Atul, AtulHumar Diagnostics: Angela M. Caliendo, Lattes, R, Abate, D, Kotton, Camille N, Roberta Lattes, Danziger Isakov L, Pierre Merville, Lautenschlager, I, Lara Danziger-Isakov, Fausto Baldanti, Glen Westall, Alain, S, Camille N. Kotton, Paget, G, Kumar, D., Emery, V, Martina Sester Prevention: Atul Humar, Jennifer Harrison, Mueller, N, Chou, Sunwen, Westall, G, Nicolas Mueller, Caliendo, AM, Transplantation Society International CMV Consensus Group Consensus Contributors Leaders: C.a.m.i.l.l.e.N. Kotton, Sophie Alain, Luis F. A. Camargo, Oriol Manuel, Ajit P. Limaye, Danziger-Isakov, L., Jutta Preiksaitis Immunology: Deepali Kumar, Caliendo AM, Chou S, Blumberg, E, Atul Humar, Caliendo, A.M., Preiksaitis, J, Irmeli Lautenschlager, Torre Cisneros, J, Morris, M, Kumar D, Kamar, N, Michele Morris, Limaye, AP   +105 more
core   +1 more source