Results 101 to 110 of about 16,112 (276)

Graph mining for next generation sequencing: leveraging the assembly graph for biological insights [PDF]

open access: yes, 2016
Total genome length estimation for NG50. This spreadsheet file contains the calculation of the average genome lengths for the complete reference sequences available through the NCBI RefSeq database for the most abundant genera in the Crohn’s and ...
Hesham Ali, Julia Warnke-Sommer
core   +8 more sources

A Guide for Spatial Omics Technologies: Innovation, Evaluation, and Application

open access: yesAdvanced Science, EarlyView.
This review presents a strategy‐centric framework for spatial omics technologies, organizing methods by how spatial information is experimentally encoded. It compares key performance trade‐offs across sequencing‐ and imaging‐based approaches, examines computational and practical limitations, and highlights biomedical applications. The analysis provides
Xiaofeng Wu   +5 more
wiley   +1 more source

Bacterial repetitive extragenic palindromic sequences are DNA targets for Insertion Sequence elements

open access: yesBMC Genomics, 2006
Background Mobile elements are involved in genomic rearrangements and virulence acquisition, and hence, are important elements in bacterial genome evolution.
Pareja Eduardo, Tobes Raquel
doaj   +1 more source

Evolution of pogo, a separate superfamily of IS630-Tc1-mariner transposons, revealing recurrent domestication events in vertebrates

open access: yesMobile DNA, 2020
s Background Tc1/mariner and Zator, as two superfamilies of IS630-Tc1-mariner (ITm) group, have been well-defined. However, the molecular evolution and domestication of pogo transposons, once designated as an important family of the Tc1/mariner ...
Bo Gao   +8 more
doaj   +1 more source

Genome-wide analysis of growth phase-dependent translational and transcriptional regulation in halophilic archaea : research article [PDF]

open access: yes, 2007
Background Differential expression of genes can be regulated on many different levels. Most global studies of gene regulation concentrate on transcript level regulation, and very few global analyses of differential translational efficiencies exist.
Hammelmann, Mathias   +7 more
core  

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

open access: yesAdvanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui   +9 more
wiley   +1 more source

Transposase interaction with the β sliding clamp: Effects on insertion sequence proliferation and transposition rate [PDF]

open access: yes, 2015
Insertion sequences (ISs) are ubiquitous and abundant mobile genetic elements in prokaryotic genomes. ISs often encode only one protein, the transposase, which catalyzes their transposition.
Amils, Ricardo   +6 more
core   +2 more sources

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

open access: yesAdvanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang   +4 more
wiley   +1 more source

Genome characteristics of facultatively symbiotic Frankia sp. strains reflect host range and host plant biogeography [PDF]

open access: yes, 2007
Soil bacteria that also form mutualistic symbioses in plants encounter two major levels of selection. One occurs during adaptation to and survival in soil, and the other occurs in concert with host plant speciation and adaptation. Actinobacteria from the
Alloisio, Nicole   +19 more
core   +2 more sources

Extensive horizontal gene transfer in cheese-associated bacteria. [PDF]

open access: yes, 2017
Acquisition of genes through horizontal gene transfer (HGT) allows microbes to rapidly gain new capabilities and adapt to new or changing environments.
Bonham, Kevin S   +2 more
core   +3 more sources

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