Results 1 to 10 of about 149,269 (182)

The Transposon Registry [PDF]

Mobile DNA, 2019
Transposable elements in prokaryotes are found in many forms and therefore a robust nomenclature system is needed in order to allow researchers to describe and search for them in publications and databases.
Supathep Tansirichaiya, Md. Ajijur Rahman, Adam P. Roberts   +2 more
doaj   +5 more sources

Abundant A-to-I RNA editing in spermatocytes may suppress transposons to compensate for piRNA downregulation in male germlines [PDF]

RNA Biology
The germline genome serves as a crucial battleground for transposon expansion, as transposons can increase their copy numbers in offspring when activated within germ cells.
Yuange Duan, Qiuhua Xie, Ling Ma, Qi Cao
doaj   +2 more sources

Tracing Mobile DNAs: From Molecular to Population Scales

Frontiers in Plant Science, 2022
Transposable elements (TEs, transposons) are mobile DNAs that are prevalent in most eukaryotic genomes. In plants, their mobility has vastly contributed to genetic diversity which is essential for adaptive changes and evolution of a species.
Wenwen Fan, Wenwen Fan, Ling Wang, Ling Wang, Jie Chu, Jie Chu, Hui Li, Hui Li, Eun Yu Kim, Jungnam Cho, Jungnam Cho, Jungnam Cho   +11 more
doaj   +1 more source

Casposase structure and the mechanistic link between DNA transposition and spacer acquisition by CRISPR-Cas

eLife, 2020
Key to CRISPR-Cas adaptive immunity is maintaining an ongoing record of invading nucleic acids, a process carried out by the Cas1-Cas2 complex that integrates short segments of foreign genetic material (spacers) into the CRISPR locus.
Alison B Hickman, Shweta Kailasan, Pavol Genzor, Astrid D Haase, Fred Dyda   +4 more
doaj   +1 more source

Novel Resistance Regions Carrying TnaphA6, bla_VIM-2, and bla_PER-1, Embedded in an ISPa40-Derived Transposon from Two Multi-Resistant Pseudomonas aeruginosa Clinical Isolates

Antibiotics, 2023
Antibiotic resistance is an alarming problem throughout the world and carbapenem-resistant Pseudomonas aeruginosa has been cataloged as critical in the World Health Organization list of microorganisms in urgent need for the development of new ...
Romina Papa-Ezdra, Nicolás F. Cordeiro, Matilde Outeda, Virginia Garcia-Fulgueiras, Lucía Araújo, Verónica Seija, Juan A. Ayala, Inés Bado, Rafael Vignoli   +8 more
doaj   +1 more source

Structural Analysis of the A Mating Type Locus and Development of the Mating Type Marker of Agaricus bisporus var. bisporus

Journal of Fungi, 2023
Karyotyping in Agaricus bisporus is crucial for both the isolation of homokaryotic strains and the confirmation of dikaryon establishment. For the verification of the karyotype, the A mating type loci of two homokaryotic strains, H39 and H97, were ...
Yeon-Jae Choi, Sujin Jung, Hyerang Eom, Thimen Hoang, Hui-Gang Han, Sinil Kim, Hyeon-Su Ro   +6 more
doaj   +1 more source

Use of a Hybrid Adeno-Associated Viral Vector Transposon System to Deliver the Insulin Gene to Diabetic NOD Mice

Cells, 2020
Previously, we used a lentiviral vector to deliver furin-cleavable human insulin (INS-FUR) to the livers in several animal models of diabetes using intervallic infusion in full flow occlusion (FFO), with resultant reversal of diabetes, restoration of ...
Que T. La, Binhai Ren, Grant J. Logan, Sharon C. Cunningham, Neeta Khandekar, Najah T. Nassif, Bronwyn A. O’Brien, Ian E. Alexander, Ann M. Simpson   +8 more
doaj   +1 more source

Developing a Universal and Efficient Method for the Rapid Selection of Stable Fluorescent Protein-Tagged Pathogenic Vibrio Species

Journal of Marine Science and Engineering, 2020
World-wide increases in Vibrio-associated diseases have been reported in aquaculture and humans in co-occurrence with increased sea surface temperatures. Twelve species of Vibrio are known to cause disease in humans, but three species dominate the number
Candice A. Thorstenson, Matthias S. Ullrich   +1 more
doaj   +1 more source

Transcriptome Profiling of Transposon-Derived Long Non-coding RNAs Response to Hormone in Strawberry Fruit Development

Frontiers in Plant Science, 2022
Strawberry is an economically grown horticulture crop required for fruit consumption. The ripening of its fruit is a complex biological process regulated by various hormones.
Xi Chen, Xi Chen, Chengdong Wang, Bing He, Zifan Wan, Zifan Wan, Yukun Zhao, Yukun Zhao, Fengqin Hu, Yuanda Lv   +9 more
doaj   +1 more source

Artificially stimulating retrotransposon activity increases mortality and accelerates a subset of aging phenotypes in Drosophila

eLife, 2022
Transposable elements (TEs) are mobile sequences of DNA that can become transcriptionally active as an animal ages. Whether TE activity is simply a by-product of heterochromatin breakdown or can contribute toward the aging process is not known.
Joyce Rigal, Ane Martin Anduaga, Elena Bitman, Emma Rivellese, Sebastian Kadener, Michael T Marr   +5 more
doaj   +1 more source