Results 21 to 30 of about 149,269 (182)

Comparative transcriptomics of multidrug-resistant Acinetobacter baumannii in response to antibiotic treatments [PDF]

open access: yes, 2018
Multidrug-resistant Acinetobacter baumannii, a major hospital-acquired pathogen, is a serious health threat and poses a great challenge to healthcare providers.
Chan, Ting-Fung   +8 more
core   +2 more sources

Optimization of universal allogeneic CAR-T cells combining CRISPR and transposon-based technologies for treatment of acute myeloid leukemia

open access: yesFrontiers in Immunology, 2023
Despite the potential of CAR-T therapies for hematological malignancies, their efficacy in patients with relapse and refractory Acute Myeloid Leukemia has been limited.
Cristina Calviño   +42 more
doaj   +1 more source

Gene transfer in the GI tract and oral cavity [PDF]

open access: yes, 2000
Gene transfer is important in spreading antibiotic resistance and other traits such as virulence factors. In this review the molecular mechanisms of gene transfer are outlined and the biological consequences of bacterial gene transfer in the GI tract and
Mullany, P
core   +1 more source

In silico reversal of repeat-induced point mutation (RIP) identifies the origins of repeat families and uncovers obscured duplicated genes [PDF]

open access: yes, 2010
Background: Repeat-induced point mutation (RIP) is a fungal genome defence mechanism guarding against transposon invasion. RIP mutates the sequence of repeated DNA and over time renders the affected regions unrecognisable by similarity search tools such ...
Hane, J.K., Oliver, R.P.
core   +4 more sources

Spread of Streptococcus suis Sequence Type 7, China

open access: yesEmerging Infectious Diseases, 2008
Streptococcus suis sequence type (ST) 7 has been spreading throughout China. To determine events associated with its emergence, we tested 114 isolates.
Changyun Ye   +15 more
doaj   +1 more source

Campylobacter jejuni genes Cj1492c and Cj1507c are involved in host cell adhesion and invasion [PDF]

open access: yes, 2020
Background Campylobacter jejuni (C. jejuni) has been assigned as an important food-borne pathogen for human health but many pathogenicity factors of C. jejuni and human host cell responses related to the infection have not yet been adequately clarified.
Alter, Thomas   +4 more
core   +1 more source

Chromatic Bacteria – A Broad Host-Range Plasmid and Chromosomal Insertion Toolbox for Fluorescent Protein Expression in Bacteria

open access: yesFrontiers in Microbiology, 2018
Differential fluorescent labeling of bacteria has become instrumental for many aspects of microbiological research, such as the study of biofilm formation, bacterial individuality, evolution, and bacterial behavior in complex environments.
Rudolf O. Schlechter   +15 more
doaj   +1 more source

In Silico Analysis of Mobilome Response to Salt Stress in Phaseolus vulgaris L.

open access: yesTürkiye Tarımsal Araştırmalar Dergisi, 2018
Common bean is an important legume that grown and consumed as animal feed and for human nutrition. It is also an important source of protein in developing countries.
Behcet İNAL
doaj   +1 more source

A self‐propagating, barcoded transposon system for the dynamic rewiring of genomic networks

open access: yesMolecular Systems Biology, 2023
In bacteria, natural transposon mobilization can drive adaptive genomic rearrangements. Here, we build on this capability and develop an inducible, self‐propagating transposon platform for continuous genome‐wide mutagenesis and the dynamic rewiring of ...
Max A English   +2 more
doaj   +1 more source

Genome-Wide Transposon Screen of a Pseudomonas syringae mexB Mutant Reveals the Substrates of Efflux Transporters. [PDF]

open access: yes, 2019
Bacteria express numerous efflux transporters that confer resistance to diverse toxicants present in their environment. Due to a high level of functional redundancy of these transporters, it is difficult to identify those that are of most importance in ...
Deutschbauer, Adam M   +4 more
core   +1 more source

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