Results 161 to 170 of about 122,409 (259)

Functional tendon regeneration is driven by regulatory T cells and IL-33 signaling. [PDF]

Sci Adv
Arvind V, Crosio G, Howell K, Zhang H, Montero A, Huang AH.   +5 more
europepmc   +1 more source

C1q+ Macrophage–Tumor Cell Interaction Promoted Tumorigenesis via GPR17/PI3K/AKT Pathway Induced DNA Hypermethylation in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
In the TME of NPC, C1q secreted by C1q+ TAMs interacted with GPR17 to activate PI3K/AKT signaling through strengthening GPR17 coupling PI3K and increasing calcium levels in tumor cells. The activated PI3K/AKT signaling further induces DNA hypermethylation to promote the malignancy and stemness of tumor cells.
Yunzhi Liu, Cuicui Huang, Min Luo, Wenfu Lu, Baifeng Zhang, Lu Bai, Shuyue Zheng, Yanan Tan, Shanshan Li, Huali Wang, Lanqi Gong, Xinyuan Guan   +11 more
wiley   +1 more source

CCR9 shapes the immune microenvironment of colorectal cancer modulating the balance between intratumoral CD8+ T cell and FoxP3+ Helios+ Treg subpopulations. [PDF]

PLoS One
Martínez-Ríos J, López-Pacheco CP, García-Zepeda EA, Soldevila G.   +3 more
europepmc   +1 more source

The aryl hydrocarbon receptor: a regulator of Th17 and Treg cell development in disease [PDF]

, 2008
Peggy P. Ho, Lawrence Steinman
openalex   +1 more source

Precision‐Guided Stealth Missiles in Biomedicine: Biological Carrier‐Mediated Nanomedicine Hitchhiking Strategy

Advanced Science, EarlyView.
Diagram illustrating the binding methods of NPs and biological barriers. The biological carrier‐mediated nanomedicine hitchhiking strategy (BCM‐NHS) utilizes two distinct techniques: the surface‐based “Backpack” method, which relies on ligand‐receptor binding, covalent conjugation, and non‐covalent binding, and the encapsulated “Trojan horse” approach,
Yuyan Zhou, Xinyue Wang, Deyu Zhang, Hanxiao Cui, Xiaorong Tian, Wei Du, Zhenghui Yang, Dongling Wan, Zhiwei Qiu, Chao Liu, Zhicheng Yang, Lizhihong Zhang, Qiusheng Yang, Xuefeng Xu, Wenhao Li, Dong Wang, Haojie Huang, Wencheng Wu   +17 more
wiley   +1 more source

Circulating differentiated and senescent lymphocyte subsets and incident diabetes risk in older adults: The Cardiovascular Health Study

Endocrinology, Diabetes &Metabolism, Volume 6, Issue 1, January 2023., 2023
This study performed a longitudinal analysis of a comprehensive panel of 22 innate and adaptive immune cell phenotypes, including differentiated and senescent CD4+ and CD8+ cells, with incident diabetes risk among a U.S. community‐based population of older adults.
Nels C. Olson, Margaret F. Doyle, Petra Buzkova, Sally A. Huber, Ian H. de Boer, Colleen M. Sitlani, Russell P. Tracy, Bruce M. Psaty, Kenneth J. Mukamal, Joseph A. Delaney   +9 more
wiley   +1 more source

Decellularized Extracellular Matrix Scaffold Loaded with Regulatory T Cell-Conditioned Medium Induces M2 Macrophage Polarization. [PDF]

Biomater Res
Jiang H, Sun X, Liu J, Fang L, Liang Y, Zhou J, Wu Y, Lin Z.   +7 more
europepmc   +1 more source

Treg Depletion–enhanced IL-2 Treatment Facilitates Therapy of Established Tumors Using Systemically Delivered Oncolytic Virus [PDF]

, 2008
Timothy Kottke, Feorillo Galivo, Phonphimon Wongthida, Rosa María Díaz, Jill Thompson, Dragan Jevremović, Glen N. Barber, Geoff Hall, John Chester, Peter J. Selby, Kevin J. Harrington, Alan Melcher, Richard G. Vile   +12 more
openalex   +1 more source

Integrin‐Targeted, Activatable Nanophototherapeutics for Immune Modulation: Enhancing Photoimmunotherapy Efficacy in Prostate Cancer Through Macrophage Reprogramming

Aggregate, EarlyView.
To further promote immune activation in the tumor microenvironment, tumor‐selective nanomodulators called RPST@IMQ were proposed, aiming to comprehensively activate endogenous tumor immunity by inducing death of immunogenic cancer cells and remodeling the tumor microenvironment, which demonstrated a great potential for application.
Cheng Zhang, Xiaolan Yin, Lei Hao, Yumei Wang, Linqiang Dou, Qixian Chen, Jun‐Seok Lee, Jingyun Wang, Xiaojun Peng, Juyoung Yoon, Haidong Li   +10 more
wiley   +1 more source

Facile Access to Piezoelectric Polyamides by Polyamidation of Carboxylic Acids and Ynamides for Potent Tumor Immunotherapy

Angewandte Chemie, EarlyView.
We establish a simple polyamidation of carboxylic acids and ynamides to synthesize versatile piezoelectric polyamides, with the merits of 100% atom economy, no waste generation, and additive‐free as well as catalyst‐free system. Tetraphenylethene containing polyamides can generate reactive oxygen species and elicit robust immunogenic cell death ...
Xingguang Li, Ruiqi Yan, Mei Tan, Ryan T. K. Kwok, Jianwei Sun, Huijing Xiang, Xiang Ma, Jacky W. Y. Lam, Ben Zhong Tang   +8 more
wiley   +2 more sources