Results 241 to 250 of about 275,584 (397)

scPER: A Rigorous Computational Approach to Determine Cellular Subtypes in Tumors Aligned With Cancer Phenotypes From Total RNA Sequencing

Advanced Science, EarlyView.
scPER presents an adversarial‐autoencoder framework that deconvolves bulk total RNA‐seq to quantify tumor‐microenvironment cell types and uncover phenotype‐linked subclusters. Across diverse benchmarks, scPER improves accuracy over existing tools.
Bingrui Li, Xiaobo Zhou, Raghu Kalluri
wiley   +1 more source

TRIP13 promotes the expansion and immunosuppression of CD4⁺Foxp3⁺ regulatory T cells by sustaining HAT1 stability. [PDF]

Cell Death Dis
He T, Zhao L, Feng CT, Zhao LY, Jing S, Yang H, Wang K, Ye S, Zhao Y, Yu Y, Fu Z, Chou CK, Chen X, Gao YJ.   +13 more
europepmc   +1 more source

Major depression favors the expansion of Th17-like cells and decrease the proportion of CD39+Treg cell subsets in response to myelin antigen in multiple sclerosis patients

, 2022
Priscila M. Sacramento, Marisa C. Sales, Taissa de Matos Kasahara, Clarice Monteiro, Hugo Oyamada, Aleida Dias, Lana M. Lopes, Camilla Castro, Átila Duque Rossi, Lucas Mattos Milioni, Anshu Agrawal, Regina Maria Papais Alvarenga, Cláudia Cristina Ferreira Vasconcelos, Cleonice Alves de Melo Bento   +13 more
openalex   +2 more sources

GlycoChat Uncovers Glycan–Lectin Circuits in the Tumor Microenvironment of Pancreatic Cancer

Advanced Science, EarlyView.
Aberrant glycosylation drives cancer progression, yet its role in the tumor microenvironment remains unclear. We developed GlycoChat to map glycan–lectin circuits at single‐cell resolution. We discovered that cancer cells induce immunosuppressive macrophage differentiation and impair phagocytosis through interactions with CLEC10A and SIGLEC3 ...
Dinh Xuan Tuan Anh, Sunanda Keisham, Arun Burramsetty, Lalhaba Oinam, Koichiro Kumano, Akihiro Kuno, Osamu Shimomura, Tatsuya Oda, Hiroaki Tateno   +8 more
wiley   +1 more source

Discovery of Seven ROS-Sensitive Immune Checkpoints and 46 Ligands Mediating Immune Suppression Through T cell-APC Networks. [PDF]

J Cancer
Han B, Xu K, Saaoud F, Hou Y, Shao Y, Lu Y, Jiang X, Zhao H, Wang H, Yang X.   +9 more
europepmc   +1 more source

CD8+ Tregs in lupus, autoimmunity, and beyond

, 2010
Ravi K. Dinesh, Brian J. Skaggs, Antonio La Cava, Bevra H. Hahn, Ram P. Singh   +4 more
openalex   +2 more sources

Changes in Treg numbers and activity in papillary thyroid carcinoma with and without Hashimoto’s thyroiditis [PDF]

, 2020
Na Zhao, Xin Liu, Chao Wu, Yuanchao Liu, Xiangnan Zhao, Xianghui He   +5 more
openalex   +1 more source

Spatiotemporally Controlled Tumor Photodynamic/Immunotherapy Therapy Based on Upconversion Hybrid Nanosystem

Advanced Science, EarlyView.
PURH is constructed by a five‐layer upconversion nanoparticle (UCNP) surface coated with mesoporous silica, which encapsulates rose bengal (RB) within the mesoporous channels. Additionally, CpG oligonucleotides (CpG ODN) is linked to the surface, followed by the surface functionalization of hyaluronic acid (HA). This spatiotemporally controllable smart
Fang Wang, Wenfei Xu, Yuechen Liu, Shuxuan Zhu, Wenjing Liu, Shuhui Bo, Hong Sun, Bei Liu, Zhaogang Sun, Hongqian Chu   +9 more
wiley   +1 more source

Galectin-3 exacerbates autoimmune diabetes by limiting regulatory T cell differentiation and function. [PDF]

Sci Adv
Xie L, Zhang R, Zou H, Hu J, Deng J, Ding J, Liu L, Lin Q, Zhao B, Xu A, Zhou Z, Xiao Y.   +11 more
europepmc   +1 more source

The Percentage of FoxP3+Helios+ Treg Cells Correlates Positively With Disease Activity in Systemic Lupus Erythematosus

, 2013
Amit Golding, Sarfaraz Hasni, Gabor G. Illei, Ethan M. Shevach   +3 more
openalex   +2 more sources