Results 261 to 270 of about 275,584 (397)

Regulatory T-cells in Reproductive Medicine: Implications for Endometriosis-Associated Infertility and Implantation Immunity. [PDF]

Cureus
Taguchi S, Hayashi T.
europepmc   +1 more source

Alpha (v) integrins license regulatory T cells to apoptotic cells and self-associated antigens [PDF]

, 2010
A-Gonzalez, Albert, Albert, Aujla, Benson, Bluestone, Coombes, Fadok, Fadok, Finnemann, Finnemann, Freire-de-Lima, Hall, Hanayama, Hanayama, Hanayama, Hoffmann, Hsu, Huang, Huynh, Hynes, Ivanov, Ivanov, Jang, Johann, Kleinclauss, Lacy-Hulbert, Liang, Lucas, Lucas, Majai, McCarty, Miyake, Mucida, Mukundan, Nagata, Nandrot, Nishihara, Rubartelli, Savill, Savill, Savill, Schambach, Siewert, Stuart, Sugimoto, Torchinsky, Travis, Urban, Voll, Wu   +50 more
core   +1 more source

Comment on: the Regulatory Role and Mechanism of TGFBI on tregs in the immune microenvironment of clear cell renal cell carcinoma

Zhonghua Zheng, Xiaorui Li, Jingsong Sun
openalex   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

Advanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu, Ruotong Li, Li Zhang, Hengli Lu, Binhui Yang, Qian Hu, Yining Tao, Haoran Mu, Jing Han, Pengfei Zan, Jiakang Shen, Dongqing Zuo, Hongsheng Wang, Wei Sun, Xingjun Zhu   +14 more
wiley   +1 more source

IL-27 promotes Treg cell expression of CD122 and fitness at homeostasis. [PDF]

Proc Natl Acad Sci U S A
Lanzar ZR, Aldridge DL, Cruz-Morales E, Howard CA, Conway IO, Zhong Z, Eberhard JN, Pereira JA, Phan AT, Ring AM, Parker M, Kanellopoulou C, Min B, Kedl RM, Christian DA, Hunter CA.   +15 more
europepmc   +1 more source

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

Fluorescence tracking Treg movement identifies anti-CCR8 and radiation as a therapeutic combination. [PDF]

iScience
Friedman DJ, Ramin S, Blair T, Kramer G, Bambina S, Alice AF, Baird J, Medler T, Young KH, Crittenden MR, Gough MJ.   +10 more
europepmc   +1 more source

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source

Correction: REV-ERB regulates RORγt+ regulatory T cell specification and function through the Bhlhe40-c-Maf axis. [PDF]

J Exp Med
Hu X, Liu Z, Li Y, You Y, Yue K, Liang Y, Loo CS, Yu J, Leblanc M, Wang D, Li H, Zheng Y.   +11 more
europepmc   +1 more source

Old friends for breakfast [PDF]

, 2005
Brunet, LR, Rook, GAW
core   +1 more source