Results 101 to 110 of about 120,068 (304)
In vivo treatment with entinostat decreases Foxp3 expression in Tregs and inhibits Tregs function.
, 2012 BALB/c mice were treated with vehicle (0.5% methocel) or 5 mg/kg/day or 20 mg/kg/day of entinostat by gavage for 5 days. Cells were harvested from spleens and lymph nodes.
Michael Ciesielski (186052) +8 more
core +1 more source
Advanced Science, EarlyView.A supramolecular pyroptotic thermal switch encapsulates I3− within β‐cyclodextrin (β‐CD) and undergoes CaCO3 mineralization. Upon lysosomal acidification, CaCO3 is degraded, releasing Ca2+ and I3−. Concurrently, BODIPY activation converts I3− into I2, inducing oxidative stress and Ca2+ overload, which together trigger caspase‐3/GSDME‐mediated ...
Dan Wu +8 more
wiley +1 more source
Tregs in Immunotherapy: Opportunities and Challenges [PDF]
Immunotherapy, 2011 n ...
openaire +3 more sources
, 2011 We identified CD8+CD122+ regulatory T cells (Tregs) and demonstrated their importance in the maintenance of immune homeostasis and in the recovery from experimental autoimmune encephalomyelitis.
Yusuke Okuno +7 more
core +1 more source
Advanced Science, EarlyView.We developed an ultrasound‐controlled biomimetic nanoplatform, mRNA/V@M NPs, to co‐deliver CD74 mRNA and V‐9302 for fibrotic TNBC therapy. CD74 mRNA reprograms myCAFs into antigen‐presenting apCAF cells through the CD74‐MHC II pathway, while V‐9302 induces ICD and activates MHC I‐CD8+ T cell immunity.
Chen Ai +9 more
wiley +1 more source
DYSFUNCTION OF IMMUNE RESPONSE REGULATION AS A FUNDAMENTAL CAUSE OF AUTOIMMUNITY ONSET [PDF]
Biotechnologia ActaAim: To investigate the types of immune response regulation and immunological tolerance disorders in autoimmune diseases. Methods: Bibliometric indicators` analysis of scientific articles and analytical materials from databases such as Scopus, Web of ...
A. Havrylyuk +3 more
doaj +1 more source
The Application Potential of the Regulation of Tregs Function by Irisin in the Prevention and Treatment of Immune-Related Diseases [PDF]
Zhengjiang Wang,1,2,* Jiaqi Xu,1,2,* Liqun Mo,1 Renshu Zhan,1,2 Jin Zhang,3 Li Liu,1,2 Jun Jiang,4 Yingying Zhang,1,2 Yiping Bai1,2 1Department of Anesthesiology, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan Province ...
Jiang J +8 more
core
Advanced Science, EarlyView.A programmable encapsulation technology is developed to reduce bacterial immunogenicity and proliferation after systemic administration. The cross‐linked polymer networks around individual bacteria enable immunogenic shielding and permit selective proliferation in tumors, allowing the bacteria to convert tumor‐accumulated ammonia into L‐arginine and ...
Jianhui Yang +12 more
wiley +1 more source
15-PGDH Expression in Gastric Cancer: A Potential Role in Anti-Tumor Immunity
Cancer Management and Research, 2020 Yaling Li,1– 3 Junjie Li,1 Juanjuan Dong,1 Lei Zhang,2 Dongling Liu,1,4 Jianzheng He,1– 3 Yali She,2 Chengxu Ma,2 Yongqi Liu1– 3 1Provincial-Level Key Laboratory of Molecular Medicine of Major Diseases and Study on Prevention and ...
Li Y +8 more
doaj
International Journal of Nanomedicine, 2022 Kalliopi Domvri,1 Savvas Petanidis,2,3 Paul Zarogoulidis,4 Doxakis Anestakis,5 Charalampos Charalampidis,5 Drosos Tsavlis,6 Haidong Huang,7 Lutz Freitag,8 Wolfgang Hohenforst-Schmidt,9 Dimitris Matthaios,10 Theodora Katopodi,2 Konstantinos Porpodis3 ...
Domvri K +11 more
doaj