Results 151 to 160 of about 130,982 (298)

The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease [PDF]

, 2007
Behdad Afzali, Giulia Lombardi, Robert I. Lechler, Graham M. Lord   +3 more
openalex   +1 more source

Targeted Delivery of c(RGDfk)‐Modified Liposomes to Bone Marrow Through In Vivo Hitchhiking Neutrophils for Multiple Myeloma Therapy

Advanced Science, Volume 12, Issue 12, March 27, 2025.
A novel bone marrow‐targeting strategy employs c(RGDfk)‐modified liposomes to hitchhike aging neutrophils, enabling precise drug delivery and reducing off‐target effects. These neutrophils deliver BMS‐202 to block PD‐1/PD‐L1 and carfilzomib to polarize macrophages into M1‐type, transforming the tumor microenvironment into an immunogenic state and ...
Huiwen Liu, Bo Zhang, Hongrui Chen, Honglan Wang, Xifeng Qin, Chunyan Sun, Zhiqing Pang, Yu Hu   +7 more
wiley   +1 more source

CpG DNA inhibits CD4+CD25+ Treg suppression through direct MyD88-dependent costimulation of effector CD4+ T cells [PDF]

, 2007
David F. LaRosa, Andrew E. Gelman, Adeeb Rahman, Jidong Zhang, Laurence A. Turka, Patrick Walsh   +5 more
openalex   +1 more source

The Nuclear Receptor NR1B1/RARα Arrests the Differentiation of Anti‐Tumor Effector Cytotoxic T Cells

Advanced Science, Volume 12, Issue 17, May 8, 2025.
RARα is highly expressed by differentiated effector and exhausted T cells and exerts a negative effect on effector T cell differentiation and the associated trafficking receptor switch. Upregulated RARα levels decrease the nuclear histone acetylase (HAT) activity, and this suppresses the expression of key Teff transcription factor BATF and trafficking ...
Patrick Niekamp, Ryun Hee Kim, Adithyan Jayaraman, Nils Klement, Raymond Kostlan, Chang H. Kim   +5 more
wiley   +1 more source

Acupoint Autohemotherapy Attenuates DNCB-Induced Atopic Dermatitis and Activates Regulatory T Cells in BALB/c Mice

Journal of Inflammation Research
Shi-Hua Yan,1,2 Yong Chen,3 Zhi-Qian Huang,1 Wen-Xi Zhong,1 Xiao-Tian Wang,1 Yang-Can Tang,1 Xu-Yi Zhao,1 Yu-Shan Wu,1 Chun Zhou,4 Wei Zhu,5 Wei Xiao,1,6 Xuan Li,2 Dong-Shu Zhang1,2 1School of Traditional Chinese Medicine, Southern Medical University ...
Yan SH, Chen Y, Huang ZQ, Zhong WX, Wang XT, Tang YC, Zhao XY, Wu YS, Zhou C, Zhu W, Xiao W, Li X, Zhang DS   +12 more
doaj  

Rejection of Metastatic 4T1 Breast Cancer by Attenuation of Treg Cells in Combination With Immune Stimulation [PDF]

, 2007
Li Chen, Tiangui Huang, Marcia Meseck, John Mandeli, John T. Fallon, Savio L.C. Woo   +5 more
openalex   +1 more source

NAT10 Promotes Gastric Cancer Liver Metastasis by Modulation of M2 Macrophage Polarization and Metastatic Tumor Cell Hepatic Adhesion

Advanced Science, Volume 12, Issue 15, April 17, 2025.
The N‐acetyltransferase‐10 (NAT10)‐mediated mRNA N4‐acetylcytidine modification enhances the stability of CXCL2 and KLF5 mRNA. Then, secreted CXCL2 promotes M2 macrophage polarization and oncostatin M secretion, activating NAT10 expression via STAT3 signaling.
Chen Chen, Zhangding Wang, Qingfeng Lin, Mengmeng Li, Lei Xu, Yao Fu, Xiaoya Zhao, Zhuang Ma, Jiawen Xu, Shimeng Zhou, Mingyue Zhang, Yun Qian, Linsen Bao, Bo Wang, Meng Wang, Qingqing Ding, Qiang Wang, Shouyu Wang   +17 more
wiley   +1 more source

The role of disease stage, plasma viral load and regulatory T cells (Tregs) on autoantibody production in SIV-infected non-human primates [PDF]

, 2007
Aftab A. Ansari, Lara Pereira, Ann E. Mayne, Nattawat Onlamoon, Kovit Pattanapanyasat, Kazuyasu Mori, François Villinger   +6 more
openalex   +1 more source

Correlation Between Fecal Microbiota and Corticosteroid Responsiveness in Primary Immune Thrombocytopenia: an Exploratory Study

Advanced Science, EarlyView.
This study uses gut microbiome data to predict corticosteroid response in patients with immune thrombocytopenia (ITP). Fecal samples from 212 patients with ITP are sequenced. Six machine‐learning algorithms are used to train predictive models. The support vector machine‐based model integrated clinical data and selected microbial species, diversities ...
Feng‐Qi Liu, Zhuo‐Yu An, Li‐Juan Cui, Meng‐Yu Xiao, Ye‐Jun Wu, Wei Li, Bang‐Shuo Zhang, Li Yu, Jia Feng, Zhuo‐Gang Liu, Ru Feng, Zhong‐Xing Jiang, Rui‐Bin Huang, Hong‐Mei Jing, Jin‐Hai Ren, Xiao‐Yu Zhu, Yun‐Feng Cheng, Yu‐Hua Li, He‐Bing Zhou, Da Gao, Yi Liu, Fan Yu, Xin Wang, Jian‐Lin Qiao, Dai‐Hong Hu, Lu‐Lu Wang, Meng‐Tong Zang, Qi Chen, Qing‐Yuan Qu, Jian‐Ying Zhou, Meng‐Lin Li, Yu‐Xiu Chen, Qiu‐Sha Huang, Hai‐Xia Fu, Yue‐Ying Li, Qian‐Fei Wang, Xiao‐Jun Huang, Xiao‐hui Zhang, the Cooperative ITP Working Group   +38 more
wiley   +1 more source

Thymocyte/Splenocyte-Derived CD4+CD25+Treg Stimulated by Anti-CD200R2 Derived Dendritic Cells Suppress Mixed Leukocyte Cultures and Skin Graft Rejection

, 2006
Reginald M. Gorczynski
openalex   +1 more source